Novel role of fumarate metabolism in dahl-salt sensitive hypertension.
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Increased mitochondrial activity in renal proximal tubule cells from young spontaneously hypertensive ratsReconstruction and analysis of correlation networks based on GC-MS metabolomics data for young hypertensive men.Ultrastructure of mitochondria and the endoplasmic reticulum in renal tubules of Dahl salt-sensitive rats.Characterization of biological pathways associated with a 1.37 Mbp genomic region protective of hypertension in Dahl S rats.Dynamic convergence and divergence of renal genomic and biological pathways in protection from Dahl salt-sensitive hypertensionMitochondrial polymorphisms in rat genetic models of hypertension.MicroRNA-target pairs in human renal epithelial cells treated with transforming growth factor beta 1: a novel role of miR-382.Identification of the catalytic mechanism and estimation of kinetic parameters for fumarase.Salt-induced renal injury in SHRs is mediated by AT1 receptor activation.Reactive oxygen species as important determinants of medullary flow, sodium excretion, and hypertensionBase-resolution maps of 5-methylcytosine and 5-hydroxymethylcytosine in Dahl S rats: effect of salt and genomic sequenceAnalysis of metabolites in plasma reveals distinct metabolic features between Dahl salt-sensitive rats and consomic SS.13(BN) rats.Evidence for a link between gut microbiota and hypertension in the Dahl rat.Renalase contributes to the renal protection of delayed ischaemic preconditioning via the regulation of hypoxia-inducible factor-1α.Mitochondrial proteomic analysis reveals deficiencies in oxygen utilization in medullary thick ascending limb of Henle in the Dahl salt-sensitive rat.Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats.MicroRNAs contribute to the maintenance of cell-type-specific physiological characteristics: miR-192 targets Na+/K+-ATPase β1.Renal Tumor Necrosis Factor α Contributes to Hypertension in Dahl Salt-Sensitive Rats.miR-29c is downregulated in renal interstitial fibrosis in humans and rats and restored by HIF-α activation.Increased proliferative cells in the medullary thick ascending limb of the loop of Henle in the Dahl salt-sensitive ratDelayed ischemic preconditioning contributes to renal protection by upregulation of miR-21Inborn and acquired metabolic defects in cancer.Renal medullary microRNAs in Dahl salt-sensitive rats: miR-29b regulates several collagens and related genes.Undernutrition upregulates fumarate hydratase in the rat nucleus accumbens.Combined metabolomic and correlation networks analyses reveal fumarase insufficiency altered amino acid metabolism.Elevation of fumarase attenuates hypertension and can result from a nonsynonymous sequence variation or increased expression depending on rat strain.Transcriptomic analysis reveals inflammatory and metabolic pathways which are regulated by renal perfusion pressure in the outer medulla of Dahl-S rats.Urinary Metabolites Associated with Blood Pressure on a Low- or High-Sodium Diet.
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Novel role of fumarate metabolism in dahl-salt sensitive hypertension.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 22 June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Novel role of fumarate metabolism in dahl-salt sensitive hypertension.
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Novel role of fumarate metabolism in dahl-salt sensitive hypertension.
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type
label
Novel role of fumarate metabolism in dahl-salt sensitive hypertension.
@en
Novel role of fumarate metabolism in dahl-salt sensitive hypertension.
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prefLabel
Novel role of fumarate metabolism in dahl-salt sensitive hypertension.
@en
Novel role of fumarate metabolism in dahl-salt sensitive hypertension.
@nl
P2093
P2860
P1433
P1476
Novel role of fumarate metabolism in dahl-salt sensitive hypertension.
@en
P2093
Allen W Cowley
Andrew S Greene
Domagoj Mladinov
Kristie Usa
Mingyu Liang
Xiaoqiang Ding
Zhongmin Tian
P2860
P304
P356
10.1161/HYPERTENSIONAHA.109.129528
P407
P577
2009-06-22T00:00:00Z