The leukemic stem cell niche: current concepts and therapeutic opportunities.
about
CRIF1 interacting with CDK2 regulates bone marrow microenvironment-induced G0/G1 arrest of leukemia cellsStem Cell Modeling of Core Binding Factor Acute Myeloid LeukemiaHumanized hemato-lymphoid system miceHow I treat pediatric acute myeloid leukemiaHigh-Throughput Single-Cell Labeling (Hi-SCL) for RNA-Seq Using Drop-Based MicrofluidicsMEIS1-mediated transactivation of synaptotagmin-like 1 promotes CXCL12/CXCR4 signaling and leukemogenesis.Update on acute myeloid leukemia stem cells: New discoveries and therapeutic opportunitiesConcise Review: CXCR4/CXCL12 Signaling in Immature Hematopoiesis--Lessons From Pharmacological and Genetic ModelsCancer stem cells in basic science and in translational oncology: can we translate into clinical application?Human TM9SF4 Is a New Gene Down-Regulated by Hypoxia and Involved in Cell Adhesion of Leukemic CellsTGF-β family signaling in stem cellsBone marrow stromal cells modulate mouse ENT1 activity and protect leukemia cells from cytarabine induced apoptosisPronounced hypoxia in models of murine and human leukemia: high efficacy of hypoxia-activated prodrug PR-104Quantifying adhesion mechanisms and dynamics of human hematopoietic stem and progenitor cellsHuman extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironmentLow expression of Abelson interactor-1 is linked to acquired drug resistance in Bcr-Abl-induced leukemia.Aging of the microenvironment influences clonality in hematopoiesis.Angiocrine factors deployed by tumor vascular niche induce B cell lymphoma invasiveness and chemoresistanceThe hematopoietic stem cell niche.Qki deficiency maintains stemness of glioma stem cells in suboptimal environment by downregulating endolysosomal degradation.Evidence for organ-specific stem cell microenvironmentsThe phosphatidylinositol 3-kinase/Akt/mTOR signaling network as a therapeutic target in acute myelogenous leukemia patients.Decreased SFRP2 expression is associated with intermediate and poor karyotypes in de novo acute myeloid leukemiaAngiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells.Contribution of an aged microenvironment to aging-associated myeloproliferative disease.Osteoblasts as leukemia-initiating cells.Hyaluronan inhibits postchemotherapy tumor regrowth in a colon carcinoma xenograft model.Cediranib/AZD2171 inhibits bone and brain metastasis in a preclinical model of advanced prostate cancer.Interleukin-18 produced by bone marrow-derived stromal cells supports T-cell acute leukaemia progressionModulating the stem cell niche for tissue regeneration.Integrins and bone metastasis: integrating tumor cell and stromal cell interactions.Notch1-induced T cell leukemia can be potentiated by microenvironmental cues in the spleen.Visualising the cross-level relationships between pathological and physiological processes and gene expression: analyses of haematological diseasesDeficiency of lipid phosphatase SHIP enables long-term reconstitution of hematopoietic inductive bone marrow microenvironment.Biology, risk stratification, and therapy of pediatric acute leukemias: an update.Multiple drug resistance due to resistance to stem cells and stem cell treatment progress in cancer (Review).E- and p-selectins are essential for repopulation of chronic myelogenous and chronic eosinophilic leukemias in a scid mouse xenograft modelAdaptation of leukemia cells to hypoxic condition through switching the energy metabolism or avoiding the oxidative stressThe dominant negative β isoform of the glucocorticoid receptor is uniquely expressed in erythroid cells expanded from polycythemia vera patients.Differential niche and Wnt requirements during acute myeloid leukemia progression
P2860
Q24336990-BD70A963-4A4E-466D-9FF0-68A9EC24D230Q26765858-A53CAB0E-16E7-4922-825C-B93F9B2952CDQ26771440-D00103B3-4015-4910-AB54-7B0D54EC4109Q26992280-BDEC0C28-0E58-4D1D-9844-91E3787B09EAQ27317799-0EDC4B8C-130E-46E3-A45A-C4F1C6190C9BQ27331832-92924592-65A8-4B1C-A443-26B875D906C5Q28071384-212DF105-1B72-4A02-82BF-DFC322F6A5D1Q28080830-24DEDA91-7FB5-4D6A-BC0E-EEF9AD9458A9Q28081844-4D61A3B5-DBD2-4DC1-A7BC-AD87D93EBFF4Q28117014-A99F579B-BB7B-4E45-8C72-C9E2AC78CB64Q28274611-A7380100-3D68-402C-AC86-67F0976399D6Q28483881-C01B3B6F-C6CC-4D3D-AC9B-6E50F6E00510Q28741513-21F23673-D837-4C41-9ACA-CFBF95F4595FQ30358968-BC6BC15A-5E1E-4485-83AB-6D35E5850A44Q30514797-528A9CFB-7F4E-481F-AE93-067AB327C5C0Q30588887-D6EB1FA3-2AD0-4D10-9677-ECEB6964FA0DQ31081388-2EFCF2E0-727D-41FC-BD58-7DDA155202C8Q33598375-FBE0BA5B-B2A6-4109-B0F6-33FE80F1188AQ33607827-800C8100-647F-46B5-A8F7-01452519FCDCQ33752387-A91DE692-C943-4E9D-9146-50FBE2F0EB7BQ33915577-9827BC5D-3826-4E68-88F0-9237CB827744Q34024558-25C0C73B-AC8D-4D2D-9C35-48D7276CC02DQ34121336-587D9545-56CF-406B-9321-7EF469F1E9E1Q34145472-76D5AA9F-A836-4D82-BE05-99261405F543Q34171027-46B815D5-8F3F-4A31-9EAD-7F6B6476697FQ34171839-339301F3-F9E2-4BD0-9F4F-DFFC094C8666Q34300214-2A9D7825-2037-46BA-BBDF-0E9E6F083D2EQ34340825-0F40CCF3-6BD3-470F-8FDE-E5FB3BE21AAFQ34372296-03B563AF-527D-431C-AB3F-4FAEEB8C4ED1Q34432431-81736D15-D1F2-4246-BFC6-D8A326B59AD4Q34441622-7263AB33-E980-4B73-AA4F-235B4738B612Q34499490-F1C9806A-4BB3-4BF9-AE29-62C1CC3B9534Q34542542-0A0E2C9C-2B8C-4837-9380-2C1A1C349874Q34751252-0C7FD154-4CB1-4CFF-9F7D-3A0FDED8F2FDQ34764504-C514AE9E-4220-4B14-A2CF-F2B6AA204089Q34795591-9D7A6EBE-C363-433C-9246-BB84A2671C25Q34906157-361B4764-9F2D-4AF0-96FD-01EE23BC871CQ35088910-B17C68D5-6B5F-4816-A8B4-2BE6E0ED9F81Q35112255-C068F208-426E-427E-9FA2-22466B962941Q35212397-04C0F5BC-4A85-4A84-B0AA-3F589262D23F
P2860
The leukemic stem cell niche: current concepts and therapeutic opportunities.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 28 April 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The leukemic stem cell niche: current concepts and therapeutic opportunities.
@en
The leukemic stem cell niche: current concepts and therapeutic opportunities.
@nl
type
label
The leukemic stem cell niche: current concepts and therapeutic opportunities.
@en
The leukemic stem cell niche: current concepts and therapeutic opportunities.
@nl
prefLabel
The leukemic stem cell niche: current concepts and therapeutic opportunities.
@en
The leukemic stem cell niche: current concepts and therapeutic opportunities.
@nl
P2093
P2860
P1433
P1476
The leukemic stem cell niche: current concepts and therapeutic opportunities.
@en
P2093
D Gary Gilliland
David T Scadden
Steven W Lane
P2860
P304
P356
10.1182/BLOOD-2009-01-202606
P407
P577
2009-04-28T00:00:00Z