SCR7 is neither a selective nor a potent inhibitor of human DNA ligase IV
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Bridging of double-stranded breaks by the nonhomologous end-joining ligation complex is modulated by DNA end chemistry.Next-generation mammalian genetics toward organism-level systems biologyThe Role of the Core Non-Homologous End Joining Factors in Carcinogenesis and Cancer.Targeting DNA repair and replication stress in the treatment of ovarian cancer.DNA Ligase IV Guides End-Processing Choice during Nonhomologous End Joining.Disruption of diphthamide synthesis genes and resulting toxin resistance as a robust technology for quantifying and optimizing CRISPR/Cas9-mediated gene editing.Control of gene editing by manipulation of DNA repair mechanisms.Highly Efficient and Versatile Plasmid-Based Gene Editing in Primary T Cells.Targeting repair pathways with small molecules increases precise genome editing in pluripotent stem cells.The road less traveled: strategies to enhance the frequency of homology-directed repair (HDR) for increased efficiency of CRISPR/Cas-mediated transgenesisReproducibility: Check your chemistry
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SCR7 is neither a selective nor a potent inhibitor of human DNA ligase IV
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 07 May 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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SCR7 is neither a selective nor a potent inhibitor of human DNA ligase IV
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SCR7 is neither a selective nor a potent inhibitor of human DNA ligase IV.
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type
label
SCR7 is neither a selective nor a potent inhibitor of human DNA ligase IV
@en
SCR7 is neither a selective nor a potent inhibitor of human DNA ligase IV.
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prefLabel
SCR7 is neither a selective nor a potent inhibitor of human DNA ligase IV
@en
SCR7 is neither a selective nor a potent inhibitor of human DNA ligase IV.
@nl
P2093
P2860
P1433
P1476
SCR7 is neither a selective nor a potent inhibitor of human DNA ligase IV
@en
P2093
Alan E Tomkinson
George E Greco
Michael R Lieber
Rhys C Brooks
Zhengfei Lu
P2860
P356
10.1016/J.DNAREP.2016.04.004
P577
2016-05-07T00:00:00Z