The role of STAT-3 in the induction of apoptosis in pancreatic cancer cells by benzyl isothiocyanate.
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Cancer chemoprevention with dietary isothiocyanates mature for clinical translational researchMolecular targets of isothiocyanates in cancer: recent advancesTargeting mitochondrial STAT3 with the novel phospho-valproic acid (MDC-1112) inhibits pancreatic cancer growth in miceBenzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells.Pancreatic tumor suppression by benzyl isothiocyanate is associated with inhibition of PI3K/AKT/FOXO pathway.Deguelin suppresses pancreatic tumor growth and metastasis by inhibiting epithelial-to-mesenchymal transition in an orthotopic model.Inhibition of Integrin-HER2 signaling by Cucurbitacin B leads to in vitro and in vivo breast tumor growth suppressionMechanism of action of phenethylisothiocyanate and other reactive oxygen species-inducing anticancer agentsPenfluridol suppresses glioblastoma tumor growth by Akt-mediated inhibition of GLI1.BITC Sensitizes Pancreatic Adenocarcinomas to TRAIL-induced Apoptosisα-Mangostin: a dietary antioxidant derived from the pericarp of Garcinia mangostana L. inhibits pancreatic tumor growth in xenograft mouse model.Role of mitochondrial electron transport chain complexes in capsaicin mediated oxidative stress leading to apoptosis in pancreatic cancer cells.Activation of checkpoint kinase 2 by 3,3'-diindolylmethane is required for causing G2/M cell cycle arrest in human ovarian cancer cells.Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-α/VEGF/Rho-GTPases: pivotal role of STAT-3.Cucurbitacin B, a novel in vivo potentiator of gemcitabine with low toxicity in the treatment of pancreatic cancer.Diindolylmethane suppresses ovarian cancer growth and potentiates the effect of cisplatin in tumor mouse model by targeting signal transducer and activator of transcription 3 (STAT3).Benzyl isothiocyanate-mediated inhibition of histone deacetylase leads to NF-kappaB turnoff in human pancreatic carcinoma cells.Enhanced anti-tumor activity by the combination of the natural compounds (-)-epigallocatechin-3-gallate and luteolin: potential role of p53Critical role of STAT3 in melanoma metastasis through anoikis resistanceAntitumor activity of phenethyl isothiocyanate in HER2-positive breast cancer models.Effect of orally administered phenethyl isothiocyanate on hepatic gene expression in ratsTransient receptor potential ion channel Trpm7 regulates exocrine pancreatic epithelial proliferation by Mg2+-sensitive Socs3a signaling in development and cancer.HER2 mediated de novo production of TGFβ leads to SNAIL driven epithelial-to-mesenchymal transition and metastasis of breast cancerPhenethyl isothiocyanate: a comprehensive review of anti-cancer mechanisms.The Role of Nutraceuticals in Pancreatic Cancer Prevention and Therapy: Targeting Cellular Signaling, MicroRNAs, and Epigenome.STAT3 induces anoikis resistance, promotes cell invasion and metastatic potential in pancreatic cancer cells.Proteomic identification of binding targets of isothiocyanates: A perspective on techniques.Piperine causes G1 phase cell cycle arrest and apoptosis in melanoma cells through checkpoint kinase-1 activation.Proteins as binding targets of isothiocyanates in cancer prevention.Dietary isothiocyanate-induced apoptosis via thiol modification of DNA topoisomerase IIα.PEITC treatment suppresses myeloid derived tumor suppressor cells to inhibit breast tumor growth.Expression of the platelet-activating factor receptor enhances benzyl isothiocyanate-induced apoptosis in murine and human melanoma cellsThe molecular basis that unifies the metabolism, cellular uptake and chemopreventive activities of dietary isothiocyanates.Inhibition of β-catenin signaling suppresses pancreatic tumor growth by disrupting nuclear β-catenin/TCF-1 complex: critical role of STAT-3.Regulation of macroautophagy in ovarian cancer cells in vitro and in vivo by controlling glucose regulatory protein 78 and AMPK.Apoptosis signal-regulating kinase 1-thioredoxin complex dissociation by capsaicin causes pancreatic tumor growth suppression by inducing apoptosis.Plumbagin, a plant derived natural agent inhibits the growth of pancreatic cancer cells in in vitro and in vivo via targeting EGFR, Stat3 and NF-κB signaling pathways.Overexpression of Mcl-1 confers resistance to BRAFV600E inhibitors alone and in combination with MEK1/2 inhibitors in melanoma.Penfluridol: An Antipsychotic Agent Suppresses Metastatic Tumor Growth in Triple-Negative Breast Cancer by Inhibiting Integrin Signaling Axis.Pancreatic cancer chemoprevention by phytochemicals
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The role of STAT-3 in the induction of apoptosis in pancreatic cancer cells by benzyl isothiocyanate.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 27 January 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The role of STAT-3 in the indu ...... ells by benzyl isothiocyanate.
@en
The role of STAT-3 in the indu ...... ells by benzyl isothiocyanate.
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type
label
The role of STAT-3 in the indu ...... ells by benzyl isothiocyanate.
@en
The role of STAT-3 in the indu ...... ells by benzyl isothiocyanate.
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prefLabel
The role of STAT-3 in the indu ...... ells by benzyl isothiocyanate.
@en
The role of STAT-3 in the indu ...... ells by benzyl isothiocyanate.
@nl
P2860
P356
P1476
The role of STAT-3 in the indu ...... ells by benzyl isothiocyanate.
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P2093
Ravi P Sahu
Sanjay K Srivastava
P2860
P304
P356
10.1093/JNCI/DJN470
P407
P577
2009-01-27T00:00:00Z