Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide. - Wikidata - wikimedia - TriplyDB

Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide.

Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide.

http://www.wikidata.org/entity/Q37303380

about

Endothelin-converting enzymes and related metalloproteases in Alzheimer's disease Catalytically distinct states captured in a crystal lattice: the substrate-bound and scavenger states of acylaminoacyl peptidase and their implications for functionality Multidimensional profiling platforms reveal metabolic dysregulation caused by organophosphorus pesticides Assessing biomarkers and neuropsychological outcomes in rural populations exposed to organophosphate pesticides in Chile--study design and protocol Activity-based protein profiling of organophosphorus and thiocarbamate pesticides reveals multiple serine hydrolase targets in mouse brain Chlorpyrifos-, diisopropylphosphorofluoridate-, and parathion-induced behavioral and oxidative stress effects: are they mediated by analogous mechanisms of action?APEH Inhibition Affects Osteosarcoma Cell Viability via Downregulation of the Proteasome.Lens crystallin modifications and cataract in transgenic mice overexpressing acylpeptide hydrolase.Are amyloid-degrading enzymes viable therapeutic targets in Alzheimer's disease?Proteolytic degradation of amyloid β-protein.Aβ degradation or cerebral perfusion? Divergent effects of multifunctional enzymes.Amyloid beta: structure, biology and structure-based therapeutic development.Platelet-activating factor antagonists enhance intracellular degradation of amyloid-β42 in neurons via regulation of cholesterol ester hydrolases.In Vivo Sub-chronic Treatment with Dichlorvos in Young Rats Promotes Synaptic Plasticity and Learning by a Mechanism that Involves Acylpeptide Hydrolase Instead of Acetylcholinesterase Inhibition. Correlation with Endogenous β-Amyloid Levels.Expression, purification, crystallization and preliminary X-ray diffraction analysis of acylpeptide hydrolase from Deinococcus radiodurans.A novel class of bifunctional acylpeptide hydrolases--potential role in the antioxidant defense systems of the Antarctic fish Trematomus bernacchii.Low Erythrocyte Levels of Proteasome and Acyl-Peptide Hydrolase (APEH) Activities in Alzheimer's Disease: A Sign of Defective Proteostasis?Stimulating the Activity of Amyloid-Beta Degrading Enzymes: A Novel Approach for the Therapeutic Manipulation of Amyloid-Beta Levels.

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P2860

Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide.

http://www.wikidata.org/entity/Q37303380

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 23 July 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide.

@en

Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide.

@nl

type

label

Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide.

@en

Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide.

@nl

prefLabel

Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide.

@en

Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide.

@nl

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Molecular Neurodegeneration

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Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide

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Ann C McKee

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Cheng Zhao

http://www.w3.org/2001/XMLSchema#string

Peter B O'Connor

http://www.w3.org/2001/XMLSchema#string

Rina Yamin

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P2860

Acyl peptide hydrolase, a serine proteinase isolated from conditioned medium of neuroblastoma cells, degrades the amyloid-beta peptide

Regional and cellular distribution patterns of insulin-degrading enzyme in the adult human brain and pituitary

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

Reduced hippocampal insulin-degrading enzyme in late-onset Alzheimer's disease is associated with the apolipoprotein E-epsilon4 allele

Neuropathological stageing of Alzheimer-related changes

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition

Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

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33

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scholarly article

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10.1186/1750-1326-4-33

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4

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Carmela R Abraham

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2009-07-23T00:00:00Z

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26690924

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1036362151

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19627603

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2726140

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