L-type calcium channel C terminus autoregulates transcription
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Signature Channels of Excitability no More: L-Type Channels in Immune CellsL-type calcium channels as drug targets in CNS disordersVoltage-gated calcium channelsThe cardiac L-type calcium channel distal carboxy terminus autoinhibition is regulated by calcium.Cyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocyte NFAT activation Novel mechanism of cardiac stress modulation by PDE5 inhibitionAutoregulation of cardiac l-type calcium channels.Mutations in the cardiac L-type calcium channel associated with inherited J-wave syndromes and sudden cardiac death.A promoter in the coding region of the calcium channel gene CACNA1C generates the transcription factor CCAT.Rem GTPase interacts with the proximal CaV1.2 C-terminus and modulates calcium-dependent channel inactivationDeletion of the distal C terminus of CaV1.2 channels leads to loss of beta-adrenergic regulation and heart failure in vivo.Functional roles of a C-terminal signaling complex of CaV1 channels and A-kinase anchoring protein 15 in brain neurons.Ca(V)1.2 channel N-terminal splice variants modulate functional surface expression in resistance size artery smooth muscle cellsDistal C terminus of CaV1.2 channels plays a crucial role in the neural differentiation of dental pulp stem cellsRegulation of gene transcription by voltage-gated L-type calcium channel, Cav1.3.Regulation of voltage-gated calcium channels by proteolysis.Apparent lack of physical or functional interaction between CaV1.1 and its distal C terminus.Different subcellular populations of L-type Ca2+ channels exhibit unique regulation and functional roles in cardiomyocytesRole of calcium and calpain in the downregulation of voltage-gated sodium channel expression by the pyrethroid pesticide deltamethrinFunctional Characterization of Schizophrenia-Associated Variation in CACNA1C.Rem-GTPase regulates cardiac myocyte L-type calcium current.Ca2+-dependent transcriptional control of Ca2+ homeostasis.Loss of Rad-GTPase produces a novel adaptive cardiac phenotype resistant to systolic decline with aging.L-type calcium channel auto-regulation of transcription.Phenotypical manifestations of mutations in the genes encoding subunits of the cardiac voltage-dependent L-type calcium channelMultilayered regulation of cardiac ion channels.The other side of cardiac Ca(2+) signaling: transcriptional control.Vascular smooth muscle cell phenotype is defined by Ca2+-dependent transcription factors.L-type CaV1.2 calcium channels: from in vitro findings to in vivo function.The role of auxiliary subunits for the functional diversity of voltage-gated calcium channels.L-type Ca2+ channels in heart and brainTruncation of murine CaV1.2 at Asp-1904 results in heart failure after birth.Calcium-dependent Nedd4-2 upregulation mediates degradation of the cardiac sodium channel Nav1.5: implications for heart failure.Neuromuscular synaptic patterning requires the function of skeletal muscle dihydropyridine receptors.Molecular and Functional Characterization of Rare CACNA1C Variants in Sudden Unexplained Death in the Young.The interplay between genetic and bioelectrical signaling permits a spatial regionalisation of membrane potentials in model multicellular ensembles.Ion flux dependent and independent functions of ion channels in the vertebrate heart: lessons learned from zebrafish.Molecular mechanism of calcium channel regulation in the fight-or-flight response.NFAT5-mediated CACNA1C expression is critical for cardiac electrophysiological development and maturation.Molecular mimicking of C-terminal phosphorylation tunes the surface dynamics of CaV1.2 calcium channels in hippocampal neurons.Protein kinase C enhances plasma membrane expression of cardiac L-type calcium channel, CaV1.2.
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L-type calcium channel C terminus autoregulates transcription
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 21 May 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
L-type calcium channel C terminus autoregulates transcription
@en
L-type calcium channel C terminus autoregulates transcription.
@nl
type
label
L-type calcium channel C terminus autoregulates transcription
@en
L-type calcium channel C terminus autoregulates transcription.
@nl
prefLabel
L-type calcium channel C terminus autoregulates transcription
@en
L-type calcium channel C terminus autoregulates transcription.
@nl
P2093
P2860
P1433
P1476
L-type calcium channel C terminus autoregulates transcription
@en
P2093
Elizabeth Schroder
Jonathan Satin
Miranda Byse
P2860
P304
P356
10.1161/CIRCRESAHA.108.191387
P577
2009-05-21T00:00:00Z