The distribution of BRAF gene fusions in solid tumors and response to targeted therapy.
about
Discovering and understanding oncogenic gene fusions through data intensive computational approachesFluorescence in situ hybridization in surgical pathology: principles and applications.A new GTF2I-BRAF fusion mediating MAPK pathway activation in pilocytic astrocytoma.Integrating Genomics Into Clinical Pediatric Oncology Using the Molecular Tumor Board at the Memorial Sloan Kettering Cancer Center.Landscape of gene fusions in epithelial cancers: seq and ye shall find.Comprehensive Genomic Profiling Facilitates Implementation of the National Comprehensive Cancer Network Guidelines for Lung Cancer Biomarker Testing and Identifies Patients Who May Benefit From Enrollment in Mechanism-Driven Clinical Trials.AGK-BRAF gene fusion is a recurrent event in sporadic pediatric thyroid carcinoma.Oncogenic BRAF fusions in mucosal melanomas activate the MAPK pathway and are sensitive to MEK/PI3K inhibition or MEK/CDK4/6 inhibition.Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.Beyond the BRAFV600E hotspot: biology and clinical implications of rare BRAF gene mutations in melanoma patients.A review of kinase fusions in melanocytic tumors.Kinase gene fusions in defined subsets of melanoma.An extremely rare case of concurrent BRAF V600E mutation driven hairy cell leukemia and melanoma: case report and review of literature.Alternative genetic mechanisms of BRAF activation in Langerhans cell histiocytosis.Overcoming resistance to single-agent therapy for oncogenic BRAF gene fusions via combinatorial targeting of MAPK and PI3K/mTOR signaling pathways.Beyond ALK and ROS1: RET, NTRK, EGFR and BRAF gene rearrangements in non-small cell lung cancer.TumorFusions: an integrative resource for cancer-associated transcript fusions.Identifying and Targeting Sporadic Oncogenic Genetic Aberrations in Mouse Models of Triple Negative Breast Cancer.MEK inhibitors under development for treatment of non-small-cell lung cancer.Recurrent BRAF Gene Fusions in a Subset of Pediatric Spindle Cell Sarcomas: Expanding the Genetic Spectrum of Tumors With Overlapping Features With Infantile Fibrosarcoma.Natural (and Unnatural) Small Molecules as Pharmacological Chaperones and Inhibitors in Cancer.New perspectives for targeting RAF kinase in human cancer.Recurrent BRAF Gene Rearrangements in Myxoinflammatory Fibroblastic Sarcomas, but Not Hemosiderotic Fibrolipomatous Tumors.Neurological update: gliomas and other primary brain tumours in adults.ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer.A FISH assay efficiently screens for BRAF gene rearrangements in pancreatic acinar-type neoplasms.Fusions in solid tumours: diagnostic strategies, targeted therapy, and acquired resistance.Kinase impact assessment in the landscape of fusion genes that retain kinase domains: a pan-cancer study.The crucial role of multiomic approach in cancer research and clinically relevant outcomes.Comprehensive genomic profiling of malignant phyllodes tumors of the breast.Identification of a Recurrent LMO7-BRAF Fusion in Papillary Thyroid Carcinoma.Recurrent intragenic rearrangements of EGFR and BRAF in soft tissue tumors of infants.The dimer-dependent catalytic activity of RAF family kinases is revealed through characterizing their oncogenic mutantsMEK/CDK4,6 co-targeting is effective in a subset of NRAS, BRAF and 'wild type' melanomas
P2860
Q31083417-653BA119-0A2C-47DD-A7A9-F69306052241Q33593910-C8C69065-B491-4339-9F73-EB7040108554Q33610906-EF643BF4-1FCE-4956-BBB7-6FF100C628F1Q33677392-A51C98F0-9BD6-48FD-A9F9-D83D4EE1222AQ36383369-85FFB0C2-F094-48FE-BEEA-093F37519B09Q37017060-4DA1DB06-D57E-4670-ABC6-F92A1CAE4B43Q37094921-2BDF9599-722C-4369-AD28-3357EAB608AAQ38721143-A90C61A6-F06D-40A5-AEDA-8192B27D6B4AQ38798543-0CEE3F99-85F3-4959-B312-F698C570DF7EQ38917480-0AED80AC-CD99-403F-9F25-FD05DD007E39Q39022023-982C5EAF-9067-468F-A50E-38D86C718EF2Q39172703-C6408370-EA15-4A98-A43C-FFD1C5C40570Q42373884-DD1A6F4D-D7E3-4185-B7C8-C4E95B37EDF2Q42774672-BC218DED-D82F-4164-80DA-087568C9D6F3Q44502910-A98C0A4C-BF76-4EE3-9A8D-65139E3FFCCDQ46512789-374E73B4-C53E-425A-B371-22BEC8DB9EB7Q47207132-87A7865D-6B2F-49B5-BAA5-5BC3B1FD35E4Q47285585-9FD53BDC-6F8C-4FC9-A0AD-A60149138647Q47318847-A72A2081-8087-4B2E-90FC-872ACC52F8BAQ47649693-B3C478D4-08B1-4B80-9287-5ADEBA4FE6C6Q47673940-FEB3B17D-2590-4335-AD12-5AE37391EF13Q47688064-2DAF073D-AE89-41A6-B926-2510E8797C54Q47704002-ADC1C835-F81B-4498-9159-9A3F1932335BQ47989137-07D89098-5A2B-4558-9FD6-5D880CFCA2E7Q49691234-59CB3EBD-0F4C-4717-9823-CFEDCB884F7BQ50200575-B67FA6B1-A606-421A-B7B3-DB324C04F175Q50251062-87E6CC27-0881-4AD4-8572-212DEB24E41EQ51237587-983C2850-E2AF-4DBC-B04A-E76B02579801Q52363678-D5F542D4-D4A4-470F-B7CC-C7E973424878Q52905583-A9518A07-652D-4045-92EE-C8E9EFFAC5BBQ54088641-A4D9250A-59E7-4F86-A5A2-A0533F7D41BBQ55289701-C3538971-0AD0-40F4-B64E-55575B365A2CQ58056531-A72A20AE-D205-4251-B9E9-2A63B7A64852Q58579036-A38B55A3-82D3-4E41-AEB9-5C1A944B2282
P2860
The distribution of BRAF gene fusions in solid tumors and response to targeted therapy.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 28 August 2015
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The distribution of BRAF gene fusions in solid tumors and response to targeted therapy.
@en
The distribution of BRAF gene fusions in solid tumors and response to targeted therapy.
@nl
type
label
The distribution of BRAF gene fusions in solid tumors and response to targeted therapy.
@en
The distribution of BRAF gene fusions in solid tumors and response to targeted therapy.
@nl
prefLabel
The distribution of BRAF gene fusions in solid tumors and response to targeted therapy.
@en
The distribution of BRAF gene fusions in solid tumors and response to targeted therapy.
@nl
P2093
P2860
P356
P1476
The distribution of BRAF gene fusions in solid tumors and response to targeted therapy.
@en
P2093
Adrienne Johnson
Brooke N Nakamura
Doron Lipson
Jacob Chudnovsky
Jeffrey S Ross
Jo-Anne Vergilio
Julia A Elvin
Laurie Gay
P2860
P304
P356
10.1002/IJC.29825
P577
2015-08-28T00:00:00Z