Conformational selection or induced fit: a flux description of reaction mechanism
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Classification of intrinsically disordered regions and proteinsInsights into Coupled Folding and Binding Mechanisms from Kinetic StudiesInsights into Protein-Ligand Interactions: Mechanisms, Models, and MethodsSeeing the invisible by paramagnetic and diamagnetic NMRPhysicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs)The concept of allosteric interaction and its consequences for the chemistry of the brainProtein flexibility in docking and surface mappingConformational selection in protein binding and functionThe roles of conditional disorder in redox proteinsTrapping conformational states along ligand-binding dynamics of peptide deformylase: the impact of induced fit on enzyme catalysisAn extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signalMolecular characterization of a family 5 glycoside hydrolase suggests an induced-fit enzymatic mechanismStructural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120Tyrosine Latching of a Regulatory Gate Affords Allosteric Control of Aromatic Amino Acid BiosynthesisThe structure of human ubiquitin in 2-methyl-2,4-pentanediol: A new conformational switchMulti-domain conformational selection underlies pre-mRNA splicing regulation by U2AFStructural Basis of the Anti-HIV Activity of the Cyanobacterial Oscillatoria Agardhii AgglutininTwisted Schiff base intermediates and substrate locale revise transaldolase mechanismReactibodies generated by kinetic selection couple chemical reactivity with favorable protein dynamicsDisparate Degrees of Hypervariable Loop Flexibility Control T-Cell Receptor Cross-Reactivity, Specificity, and Binding MechanismConformational dynamics control ubiquitin-deubiquitinase interactions and influence in vivo signalingLigand concentration regulates the pathways of coupled protein folding and binding.Structure of an Engineered β-Lactamase Maltose Binding Protein Fusion Protein: Insights into Heterotropic Allosteric RegulationEnantioselective oxidation of galactitol 1-phosphate by galactitol-1-phosphate 5-dehydrogenase from Escherichia coliEffects of Glycosylation on the Enzymatic Activity and Mechanisms of ProteasesBinding Mechanisms of Intrinsically Disordered Proteins: Theory, Simulation, and ExperimentKeep on moving: discovering and perturbing the conformational dynamics of enzymesSingle transcriptional and translational preQ1 riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structureBinding leverage as a molecular basis for allosteric regulationA role for both conformational selection and induced fit in ligand binding by the LAO proteinThe role of flexibility and conformational selection in the binding promiscuity of PDZ domainsA unified conformational selection and induced fit approach to protein-peptide dockingQuantitatively characterizing the ligand binding mechanisms of choline binding protein using Markov state model analysisHow to Distinguish Conformational Selection and Induced Fit Based on Chemical Relaxation RatesDisordered proteinaceous machinesCommon themes and differences in SAM recognition among SAM riboswitchesMg2+Shifts Ligand-Mediated Folding of a Riboswitch from Induced-Fit to Conformational SelectionExcited protein states of human tear lipocalin for low- and high-affinity ligand binding revealed by functional AB loop motion.The transition state structure for coupled binding and folding of disordered protein domains.Enhanced Local Disorder in a Clinically Elusive von Willebrand Factor Provokes High-Affinity Platelet Clumping.
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P2860
Conformational selection or induced fit: a flux description of reaction mechanism
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 30 July 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Conformational selection or induced fit: a flux description of reaction mechanism
@en
Conformational selection or induced fit: a flux description of reaction mechanism.
@nl
type
label
Conformational selection or induced fit: a flux description of reaction mechanism
@en
Conformational selection or induced fit: a flux description of reaction mechanism.
@nl
prefLabel
Conformational selection or induced fit: a flux description of reaction mechanism
@en
Conformational selection or induced fit: a flux description of reaction mechanism.
@nl
P2093
P2860
P356
P1476
Conformational selection or induced fit: a flux description of reaction mechanism
@en
P2093
Gordon G Hammes
Terrence G Oas
Yu-Chu Chang
P2860
P304
13737-13741
P356
10.1073/PNAS.0907195106
P407
P577
2009-07-30T00:00:00Z