UV-triggered affinity capture identifies interactions between the Plasmodium falciparum multidrug resistance protein 1 (PfMDR1) and antimalarial agents in live parasitized cells.
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Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy ModelingNew insight-guided approaches to detect, cure, prevent and eliminate malaria.Discovery and Characterization of ACT-451840: an Antimalarial Drug with a Novel Mechanism of Action.pfmdr1 (Plasmodium falciparum multidrug drug resistance gene 1): a pivotal factor in malaria resistance to artemisinin combination therapies.CRISPR-Cas9-modified pfmdr1 protects Plasmodium falciparum asexual blood stages and gametocytes against a class of piperazine-containing compounds but potentiates artemisinin-based combination therapy partner drugs.Hexahydroquinolines are antimalarial candidates with potent blood-stage and transmission-blocking activity.Targeting Channels and Transporters in Protozoan Parasite Infections.Recent updates in the discovery and development of novel antimalarial drug candidates
P2860
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P2860
UV-triggered affinity capture identifies interactions between the Plasmodium falciparum multidrug resistance protein 1 (PfMDR1) and antimalarial agents in live parasitized cells.
description
2013 nî lūn-bûn
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name
UV-triggered affinity capture ...... nts in live parasitized cells.
@en
UV-triggered affinity capture ...... multidrug resistance protein 1
@nl
type
label
UV-triggered affinity capture ...... nts in live parasitized cells.
@en
UV-triggered affinity capture ...... multidrug resistance protein 1
@nl
prefLabel
UV-triggered affinity capture ...... nts in live parasitized cells.
@en
UV-triggered affinity capture ...... multidrug resistance protein 1
@nl
P2093
P2860
P50
P921
P356
P1476
UV-triggered affinity capture ...... nts in live parasitized cells.
@en
P2093
Amélie Le Bihan
Bibia Heidmann
Caroline L Ng
Christoph Binkert
Christoph Boss
Corinna Mattheis
Hamed Aissaoui
Ingrid B Müller
Ithiel J Frame
Michelle Paguio
P2860
P304
22576-22583
P356
10.1074/JBC.M113.453159
P407
P577
2013-06-10T00:00:00Z