about
sameAs
Recent clinical and molecular insights into emerging artemisinin resistance in Plasmodium falciparumSupergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunateEfficient site-specific integration in Plasmodium falciparum chromosomes mediated by mycobacteriophage Bxb1 integraseSpiroindolones, a potent compound class for the treatment of malariaArtemisinin-based combination therapies: a vital tool in efforts to eliminate malariaUse of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparumUsing genetic methods to define the targets of compounds with antimalarial activityMalaria: progress, perils, and prospects for eradicationStructural elucidation of the specificity of the antibacterial agent triclosan for malarial enoyl acyl carrier protein reductaseTargeting tuberculosis and malaria through inhibition of Enoyl reductase: compound activity and structural dataA long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malariaX-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacyThe Fatty Acid Biosynthesis Enzyme FabI Plays a Key Role in the Development of Liver-Stage Malarial ParasitesOpen Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and BeyondIn vitro efficacy, resistance selection, and structural modeling studies implicate the malarial parasite apicoplast as the target of azithromycin.UDP-galactose and acetyl-CoA transporters as Plasmodium multidrug resistance genesImaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug DiscoveryPfCRT and its role in antimalarial drug resistanceEvidence for a Central Role for PfCRT in Conferring Plasmodium falciparum Resistance to Diverse Antimalarial AgentsProbing the multifactorial basis of Plasmodium falciparum quinine resistance: Evidence for a strain-specific contribution of the sodium-proton exchanger PfNHEPlasmodium falciparum Sec24 marks transitional ER that exports a model cargo via a diacidic motifStage-dependent localization of a novel gene product of the malaria parasite, Plasmodium falciparumCharacterization of a PRL protein tyrosine phosphatase from Plasmodium falciparumType II fatty acid biosynthesis is essential for Plasmodium falciparum sporozoite development in the midgut of Anopheles mosquitoesThe Mu subunit of Plasmodium falciparum clathrin-associated adaptor protein 2 modulates in vitro parasite response to artemisinin and quinineTargeting Plasmodium PI(4)K to eliminate malariaArtemisinin Action and Resistance in Plasmodium falciparumAdvances in understanding the genetic basis of antimalarial drug resistanceIdentification of a mutant PfCRT-mediated chloroquine tolerance phenotype in Plasmodium falciparumOleic acid biosynthesis in Plasmodium falciparum: characterization of the stearoyl-CoA desaturase and investigation as a potential therapeutic targetMitotic evolution of Plasmodium falciparum shows a stable core genome but recombination in antigen familiesMalaria's missing number: calculating the human component of R0 by a within-host mechanistic model of Plasmodium falciparum infection and transmissionTargeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistanceEvidence of a Mild Mutator Phenotype in Cambodian Plasmodium falciparum Malaria ParasitesEvolution of Fitness Cost-Neutral Mutant PfCRT Conferring P. falciparum 4-Aminoquinoline Drug Resistance Is Accompanied by Altered Parasite Metabolism and Digestive Vacuole PhysiologyCharacterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy ModelingTransformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanilDisruption of a Plasmodium falciparum gene linked to male sexual development causes early arrest in gametocytogenesisA novel multiple-stage antimalarial agent that inhibits protein synthesisA high susceptibility to redox imbalance of the transmissible stages of Plasmodium falciparum revealed with a luciferase-based mature gametocyte assay
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
David A Fidock
@nl
David A Fidock
@sl
David A. Fidock
@en
David A. Fidock
@es
type
label
David A Fidock
@nl
David A Fidock
@sl
David A. Fidock
@en
David A. Fidock
@es
altLabel
David Fidock
@en
prefLabel
David A Fidock
@nl
David A Fidock
@sl
David A. Fidock
@en
David A. Fidock
@es
P106
P1153
7004002430
P21
P31
P496
0000-0001-6753-8938