Activation of adenosine A(2A) receptor reduces osteoclast formation via PKA- and ERK1/2-mediated suppression of NFκB nuclear translocation
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KMUP-1 suppresses RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss: roles of MAPKs, Akt, NF-κB and calcium/calcineurin/NFATc1 pathwaysMetformin Improves Diabetic Bone Health by Re-Balancing Catabolism and Nitrogen DisposalRole and Function of A2A and A₃ Adenosine Receptors in Patients with Ankylosing Spondylitis, Psoriatic Arthritis and Rheumatoid Arthritis.Endogenous adenosine maintains cartilage homeostasis and exogenous adenosine inhibits osteoarthritis progression.Activation of EPAC1/2 is essential for osteoclast formation by modulating NFκB nuclear translocation and actin cytoskeleton rearrangementsDirect or indirect stimulation of adenosine A2A receptors enhances bone regeneration as well as bone morphogenetic protein-2.NADH oxidase-dependent CD39 expression by CD8(+) T cells modulates interferon gamma responses via generation of adenosine.Netrin-1 is a critical autocrine/paracrine factor for osteoclast differentiationCalycosin Suppresses RANKL-Mediated Osteoclastogenesis through Inhibition of MAPKs and NF-κB.The adenosine metabolite inosine is a functional agonist of the adenosine A2A receptor with a unique signaling bias.Methotrexate up-regulates ecto-5'-nucleotidase/CD73 and reduces the frequency of T lymphocytes in the glioblastoma microenvironment.MicroRNA-16 is putatively involved in the NF-κB pathway regulation in ulcerative colitis through adenosine A2a receptor (A2aAR) mRNA targetingAdenosine A2B receptors play an important role in bone homeostasis.Regulation of bone and cartilage by adenosine signaling.Osteoblastic Lrp4 promotes osteoclastogenesis by regulating ATP release and adenosine-A2AR signaling.Adenosine A1 receptor-dependent antinociception induced by inosine in mice: pharmacological, genetic and biochemical aspects.G protein coupled receptors signaling pathways implicate in inflammatory and immune response of rheumatoid arthritis.Ticagrelor regulates osteoblast and osteoclast function and promotes bone formation in vivo via an adenosine-dependent mechanism.Signaling pathways involving adenosine A2A and A2B receptors in wound healing and fibrosis.Bone regeneration in critical bone defects using three-dimensionally printed β-tricalcium phosphate/hydroxyapatite scaffolds is enhanced by coating scaffolds with either dipyridamole or BMP-2.Adenosine Receptor Stimulation Improves Glucocorticoid-Induced Osteoporosis in a Rat Model.Adenosine A2A receptor promotes collagen type III synthesis via β-catenin activation in human dermal fibroblasts.The antiviral drug tenofovir, an inhibitor of Pannexin-1-mediated ATP release, prevents liver and skin fibrosis by downregulating adenosine levels in the liver and skin.Dipyridamole enhances osteogenesis of three-dimensionally printed bioactive ceramic scaffolds in calvarial defects.Plasma membrane-bound G protein-coupled bile acid receptor attenuates liver ischemia/reperfusion injury via the inhibition of toll-like receptor 4 signaling in mice.Treatment with Adenosine Receptor Agonist Ameliorates Pain Induced by Acute and Chronic Inflammation.
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P2860
Activation of adenosine A(2A) receptor reduces osteoclast formation via PKA- and ERK1/2-mediated suppression of NFκB nuclear translocation
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Activation of adenosine A
@nl
Activation of adenosine A(2A) ...... of NFκB nuclear translocation
@en
type
label
Activation of adenosine A
@nl
Activation of adenosine A(2A) ...... of NFκB nuclear translocation
@en
prefLabel
Activation of adenosine A
@nl
Activation of adenosine A(2A) ...... of NFκB nuclear translocation
@en
P2093
P2860
P50
P356
P1476
Activation of adenosine A(2A) ...... of NFκB nuclear translocation
@en
P2093
Aránzazu Mediero
Bruce N Cronstein
Miguel Perez-Aso
P2860
P304
P356
10.1111/BPH.12227
P407
P577
2013-07-01T00:00:00Z