Initiation of (-) strand DNA synthesis from tRNA(3Lys) on lentiviral RNAs: implications of specific HIV-1 RNA-tRNA(3Lys) interactions inhibiting primer utilization by retroviral reverse transcriptases.
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Initiation of HIV-1 reverse transcription is regulated by a primer activation signalDirect and indirect contributions of RNA secondary structure elements to the initiation of HIV-1 reverse transcriptionInhibition of both HIV-1 reverse transcription and gene expression by a cyclic peptide that binds the Tat-transactivating response element (TAR) RNAPrimer tRNAs for reverse transcriptionSelection of functional tRNA primers and primer binding site sequences from a retroviral combinatorial library: identification of new functional tRNA primers in murine leukemia virus replication.Identification of specific HIV-1 reverse transcriptase contacts to the viral RNA:tRNA complex by mass spectrometry and a primary amine selective reagentChanges in Rous sarcoma virus RNA secondary structure near the primer binding site upon tRNATrp primer annealing.Structural basis for the specificity of the initiation of HIV-1 reverse transcription.Assembly, purification and crystallization of an active HIV-1 reverse transcriptase initiation complex.Coordinate roles of Gag and RNA helicase A in promoting the annealing of formula to HIV-1 RNATwo step synthesis of (-) strong-stop DNA by avian and murine reverse transcriptases in vitro.Mutational analysis of the tRNA3Lys/HIV-1 RNA (primer/template) complex.Role of HIV-1 nucleocapsid protein in HIV-1 reverse transcription.The tRNA primer activation signal in the human immunodeficiency virus type 1 genome is important for initiation and processive elongation of reverse transcriptionA cell-based strategy to assess intrinsic inhibition efficiencies of HIV-1 reverse transcriptase inhibitors.The importance of the A-rich loop in human immunodeficiency virus type 1 reverse transcription and infectivity.Identification of sequences downstream of the primer binding site that are important for efficient replication of human immunodeficiency virus type 1.Nucleotide substitutions within U5 are critical for efficient reverse transcription of human immunodeficiency virus type 1 with a primer binding site complementary to tRNA(His)Multiple biological roles associated with the Rous sarcoma virus 5' untranslated RNA U5-IR stem and loop.Mutations in HIV reverse transcriptase which alter RNase H activity and decrease strand transfer efficiency are suppressed by HIV nucleocapsid proteinSynthetic tRNALys,3 as the replication primer for the HIV-1HXB2 and HIV-1Mal genomes.Variation of human immunodeficiency virus type-1 reverse transcriptase within the simian immunodeficiency virus genome of RT-SHIV.The molecular biology of feline immunodeficiency virus (FIV).HIV-1 nucleocapsid protein and the secondary structure of the binary complex formed between tRNA(Lys.3) and viral RNA template play different roles during initiation of (-) strand DNA reverse transcription.MD simulations of HIV-1 RT primer-template complex: effect of modified nucleosides and antisense PNA oligomer.Mutating a region of HIV-1 reverse transcriptase implicated in tRNA(Lys-3) binding and the consequences for (-)-strand DNA synthesis.On the importance of the primer activation signal for initiation of tRNA(lys3)-primed reverse transcription of the HIV-1 RNA genome.Does the HIV-1 primer activation signal interact with tRNA3(Lys) during the initiation of reverse transcription?Efficient initiation of HIV-1 reverse transcription in vitro. Requirement for RNA sequences downstream of the primer binding site abrogated by nucleocapsid protein-dependent primer-template interactions.Initiation of HIV Reverse TranscriptionIn vitro evidence for the interaction of tRNA(3)(Lys) with U3 during the first strand transfer of HIV-1 reverse transcription.Genetic dissociation of the encapsidation and reverse transcription functions in the 5' R region of human immunodeficiency virus type 1The role of nucleocapsid and U5 stem/A-rich loop sequences in tRNA(3Lys) genomic placement and initiation of reverse transcription in human immunodeficiency virus type 1.Comparison of second-strand transfer requirements and RNase H cleavages catalyzed by human immunodeficiency virus type 1 reverse transcriptase (RT) and E478Q RT.Stabilization of the U5-leader stem in the HIV-1 RNA genome affects initiation and elongation of reverse transcriptionStructure-function relationships of the initiation complex of HIV-1 reverse transcription: the case of mutant viruses using tRNA(His) as primerHIV-1 Exploits a Dynamic Multi-aminoacyl-tRNA Synthetase Complex To Enhance Viral Replication.Switching the in vitro tRNA usage of HIV-1 by simultaneous adaptation of the PBS and PAS.Interaction of p55 reverse transcriptase from the Saccharomyces cerevisiae retrotransposon Ty3 with conformationally distinct nucleic acid duplexes.Molecular mimicry of human tRNALys anti-codon domain by HIV-1 RNA genome facilitates tRNA primer annealing
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P2860
Initiation of (-) strand DNA synthesis from tRNA(3Lys) on lentiviral RNAs: implications of specific HIV-1 RNA-tRNA(3Lys) interactions inhibiting primer utilization by retroviral reverse transcriptases.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Initiation of (-) strand DNA s ...... oviral reverse transcriptases.
@en
Initiation of
@nl
type
label
Initiation of (-) strand DNA s ...... oviral reverse transcriptases.
@en
Initiation of
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prefLabel
Initiation of (-) strand DNA s ...... oviral reverse transcriptases.
@en
Initiation of
@nl
P2093
P2860
P356
P1476
Initiation of (-) strand DNA s ...... roviral reverse transcriptases
@en
P2093
B Ehresmann
J W Rausch
K J Howard
M A Wainberg
S R Stetor
P2860
P304
10063-10068
P356
10.1073/PNAS.93.19.10063
P407
P577
1996-09-01T00:00:00Z