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Decoding and engineering tetracycline biosynthesis.

Decoding and engineering tetracycline biosynthesis.

http://www.wikidata.org/entity/Q37325184

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Spotlight on Antimicrobial Metabolites from the Marine Bacteria Pseudoalteromonas: Chemodiversity and Ecological Significance Crystal structure of SsfS6, the putativeC-glycosyltransferase involved in SF2575 biosynthesis Cloning and characterization of the ravidomycin and chrysomycin biosynthetic gene clusters Characterization of tetracycline modifying enzymes using a sensitive in vivo reporter system Oxytetracycline biosynthesis.The Tetracycline Destructases: A Novel Family of Tetracycline-Inactivating Enzymes.Structural insights into nonribosomal peptide enzymatic assembly lines Natural product scaffolds as leads to drugs.Probing the selectivity and protein·protein interactions of a nonreducing fungal polyketide synthase using mechanism-based crosslinkers.

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Decoding and engineering tetracycline biosynthesis.

http://www.wikidata.org/entity/Q37325184

description

article científic

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article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

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scientific article published on 22 October 2008

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

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name

Decoding and engineering tetracycline biosynthesis.

@en

Decoding and engineering tetracycline biosynthesis.

@nl

type

label

Decoding and engineering tetracycline biosynthesis.

@en

Decoding and engineering tetracycline biosynthesis.

@nl

prefLabel

Decoding and engineering tetracycline biosynthesis.

@en

Decoding and engineering tetracycline biosynthesis.

@nl

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J.YMBEN.2008.10.001

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Metabolic Engineering

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Decoding and engineering tetracycline biosynthesis.

@en

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Lauren B Pickens

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Yi Tang

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P2860

Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance

Glycylcyclines bind to the high-affinity tetracycline ribosomal binding site and evade Tet(M)- and Tet(O)-mediated ribosomal protection

The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit

Pharmacokinetics and pharmacodynamics of the tetracyclines including glycylcyclines

The antibiotic resistome: the nexus of chemical and genetic diversity

Cytotoxic activity and inhibition of tumor cell invasion by derivatives of a chemically modified tetracycline CMT-3 (COL-3).

Nomenclature for new tetracycline resistance determinants.

Altering the glycosylation pattern of bioactive compounds.

Regulation of secondary metabolism in streptomycetes.

Production of the antitumor drug epirubicin (4'-epidoxorubicin) and its precursor by a genetically engineered strain of Streptomyces peucetius.

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69-75

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scholarly article

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10.1016/J.YMBEN.2008.10.001

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2

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11

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2008-10-22T00:00:00Z

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19007902

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