Natural product scaffolds as leads to drugs. - Wikidata - wikimedia - TriplyDB

Natural product scaffolds as leads to drugs.

Natural product scaffolds as leads to drugs.

http://www.wikidata.org/entity/Q37855860

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Titration-Based Screening for Evaluation of Natural Product Extracts: Identification of an Aspulvinone Family of Luciferase Inhibitors Adaptive cellular stress pathways as therapeutic targets of dietary phytochemicals: focus on the nervous system Design, synthesis and spectroscopic characterisation of a focused library based on the polyandrocarpamine natural product scaffold.Studies toward the Development of Antiproliferative Neoclerodanes from Salvinorin A.Design and synthesis of screening libraries based on the muurolane natural product scaffold.Bioactive natural products from Papua New Guinea marine sponges.Library construction and biological evaluation of enmein-type diterpenoid analogues as potential anticancer agents.Identification of broad-spectrum antiviral compounds and assessment of the druggability of their target for efficacy against respiratory syncytial virus (RSV)A virtual screening approach for identifying plants with anti H5N1 neuraminidase activity.In situ natural product discovery via an artificial marine sponge.Induction of expression and functional activity of P-glycoprotein efflux transporter by bioactive plant natural products.De novo branching cascades for structural and functional diversity in small molecules.Silvestrol induces early autophagy and apoptosis in human melanoma cells Twelve-membered macrolactones: privileged scaffolds for the development of new therapeutics.Evaluation of pseudopteroxazole and pseudopterosin derivatives against Mycobacterium tuberculosis and other pathogens.Harnessing natural product assembly lines: structure, promiscuity, and engineering.From bortezomib to other inhibitors of the proteasome and beyond.Selective activity of deguelin identifies therapeutic targets for androgen receptor-positive breast cancer.Clustered distribution of natural product leads of drugs in the chemical space as influenced by the privileged target-sites.Discovery of scmR as a global regulator of secondary metabolism and virulence in Burkholderia thailandensis E264.Natural products with antischistosomal activity.Synthesis and Antitumor Activity of New Thiazole Nortopsentin Analogs.Antiviral activity and specific modes of action of bacterial prodigiosin against Bombyx mori nucleopolyhedrovirus in vitro.Antibiotic dialogues: induction of silent biosynthetic gene clusters by exogenous small molecules.Super Natural II--a database of natural products.Scaffold-Hopping of Aurones: 2-Arylideneimidazo[1,2-a]pyridinones as Topoisomerase IIα-Inhibiting Anticancer Agents.Dendrimers in combination with natural products and analogues as anti-cancer agents.Total Synthesis of (-)-Albocycline.In-Vitro Antiviral Activities of Extracts of Plants of The Brazilian Cerrado against the Avian Metapneumovirus (aMPV)Biology-Oriented Synthesis of a Withanolide-Inspired Compound Collection Reveals Novel Modulators of Hedgehog Signaling Structure determination of the bioactive depsipeptide xenobactin from Xenorhabdus sp. PB30.3

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P2860

Natural product scaffolds as leads to drugs.

http://www.wikidata.org/entity/Q37855860

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2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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2009年學術文章

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2009年學術文章

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Natural product scaffolds as leads to drugs.

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Natural product scaffolds as leads to drugs.

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Natural product scaffolds as leads to drugs.

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Natural product scaffolds as leads to drugs.

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Natural product scaffolds as leads to drugs.

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Natural product scaffolds as leads to drugs.

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Future Medicinal Chemistry

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Natural product scaffolds as leads to drugs.

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David J Newman

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Gordon M Cragg

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P2860

Towards a natural system of organisms: proposal for the domains Archaea, Bacteria, and Eucarya

The structure of cephalesporin C

Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance

Protein-protein interaction detection in vitro and in cells by proximity biotinylation

Structural basis for the antibiotic activity of ketolides and azalides

ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogenesis produced by Penicillium citrinium

Complete genome sequence of the myxobacterium Sorangium cellulosum

Discovery of 1-(4-fluorophenyl)-(3R)-[3-(4-fluorophenyl)-(3S)-hydroxypropyl]-(4S)-(4 -hydroxyphenyl)-2-azetidinone (SCH 58235): a designed, potent, orally active inhibitor of cholesterol absorption

The bacterial ribosome as a target for antibiotics

Thematic review series: the pathogenesis of atherosclerosis. An interpretive history of the cholesterol controversy, part V: the discovery of the statins and the end of the controversy

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1415-1427

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10.4155/FMC.09.113

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8

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21426057

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