Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis.
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Graft rejection - endogenous or allogeneic?Ethyl pyruvate is a novel anti-inflammatory agent to treat multiple inflammatory organ injuriesExtracellular HMGB1 regulates multi-walled carbon nanotube-induced inflammation in vivoHigh-mobility group box 1 and cancer.Ethyl pyruvate protects against hypoxic-ischemic brain injury via anti-cell death and anti-inflammatory mechanisms.The receptor for advanced glycation end products promotes pancreatic carcinogenesis and accumulation of myeloid-derived suppressor cells.High mobility group box 1 antagonist limits metastatic seeding in the lungs via reduction of cell-cell adhesion.DAMPening inflammation by modulating TLR signalling.Sequestering HMGB1 via DNA-conjugated beads ameliorates murine colitisToll-like receptors in inflammatory bowel diseases: a decade later.Dengue virus infection mediates HMGB1 release from monocytes involving PCAF acetylase complex and induces vascular leakage in endothelial cells.Sputum biomarkers and the prediction of clinical outcomes in patients with cystic fibrosis.HMGB1 in health and disease.Soluble HMGB1 is a novel adipokine stimulating IL-6 secretion through RAGE receptor in SW872 preadipocyte cell line: contribution to chronic inflammation in fat tissueA dual-role of Gu-4 in suppressing HMGB1 secretion and blocking HMGB1 pro-inflammatory activity during inflammation.Results of the 4th scientific workshop of the ECCO (I): pathophysiology of intestinal fibrosis in IBD.Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation.Ethyl pyruvate inhibits HMGB1 phosphorylation and release by chelating calciumPreventive effects of ethyl pyruvate on endotoxin-induced uveitis in rats.The epithelial danger signal IL-1α is a potent activator of fibroblasts and reactivator of intestinal inflammation.Overexpression of HMGB1 A-box reduced lipopolysaccharide-induced intestinal inflammation via HMGB1/TLR4 signaling in vitro.Interaction between uric acid and HMGB1 translocation and release from endothelial cells.Immunopathogenesis of IBD: current state of the art.HMGB1 Is Involved in IFN-α Production and TRAIL Expression by HIV-1-Exposed Plasmacytoid Dendritic Cells: Impact of the Crosstalk with NK CellsHMGB1 is a therapeutic target for sterile inflammation and infection.Ethyl pyruvate induces heme oxygenase-1 through p38 mitogen-activated protein kinase activation by depletion of glutathione in RAW 264.7 cells and improves survival in septic animalsDeacetylation-mediated interaction of SIRT1-HMGB1 improves survival in a mouse model of endotoxemia.Plecanatide and dolcanatide, novel guanylate cyclase-C agonists, ameliorate gastrointestinal inflammation in experimental models of murine colitis.Ethyl pyruvate ameliorates endotoxin-induced corneal inflammationHMGB1 in renal ischemic injury.A Dalbergia odorifera extract improves the survival of endotoxemia model mice by inhibiting HMGB1 release.Preservation of hepatic blood flow by direct peritoneal resuscitation improves survival and prevents hepatic inflammation following hemorrhagic shock.Persistent adaptation by chronic alcohol is facilitated by neuroimmune activation linked to stress and CRFEthyl pyruvate attenuates murine allergic rhinitis partly by decreasing high mobility group box 1 release.The cytokine mRNA increase induced by withdrawal from chronic ethanol in the sterile environment of brain is mediated by CRF and HMGB1 release.Role of the advanced glycation end products receptor in Crohn's disease inflammation.HMGB1 translocation and release mediate cigarette smoke-induced pulmonary inflammation in mice through a TLR4/MyD88-dependent signaling pathway.Anti-inflammatory and anti-excitoxic effects of diethyl oxopropanamide, an ethyl pyruvate bioisoster, exert robust neuroprotective effects in the postischemic brain.Protective effects of ethyl pyruvate on lipopolysaccharide‑induced acute lung injury through inhibition of autophagy in neutrophilsHigh-mobility group box 1, oxidative stress, and disease.
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P2860
Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 19 May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis.
@en
Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis.
@nl
type
label
Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis.
@en
Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis.
@nl
prefLabel
Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis.
@en
Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis.
@nl
P2093
P2860
P356
P1476
Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis.
@en
P2093
Antonia R Sepulveda
Donna Beer-Stolz
Fengling Li
Jeremy S Tilstra
Katsuyoshi Matsuoka
Michael T Lotze
Mitchell P Fink
Richard A DeMarco
Scott E Plevy
Shaival H Davé
P2860
P304
P356
10.1189/JLB.1008662
P577
2009-05-19T00:00:00Z