Radioresistant cervical cancer shows upregulation of the NHEJ proteins DNA-PKcs, Ku70 and Ku86.
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Beyond DNA repair: DNA-PK function in cancerChemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promisingGenotypic characteristics of resistant tumors to pre-operative ionizing radiation in rectal cancerRole of DNA-dependent protein kinase catalytic subunit in cancer development and treatmentInhibition of non-homologous end joining repair impairs pancreatic cancer growth and enhances radiation responseMicroRNAs Used in Combination with Anti-Cancer Treatments Can Enhance Therapy EfficacyCo-expression of CD147 and GLUT-1 indicates radiation resistance and poor prognosis in cervical squamous cell carcinoma.Radiosensitization and growth inhibition of cancer cells mediated by an scFv antibody gene against DNA-PKcs in vitro and in vivo.Nuclear TRADD prevents DNA damage-mediated death by facilitating non-homologous end-joining repairHigh Expression of SOX2 and OCT4 Indicates Radiation Resistance and an Independent Negative Prognosis in Cervical Squamous Cell Carcinoma.Nuclear survivin and its relationship to DNA damage repair genes in non-small cell lung cancer investigated using tissue arrayMiR-124 Radiosensitizes human colorectal cancer cells by targeting PRRX1miR-375 Modulates Radiosensitivity of HR-HPV-Positive Cervical Cancer Cells by Targeting UBE3A through the p53 Pathway.The relevance of molecular biomarkers in cervical cancer patients treated with radiotherapy.DAB2IP regulates autophagy in prostate cancer in response to combined treatment of radiation and a DNA-PKcs inhibitor.MEK inhibitor GSK1120212-mediated radiosensitization of pancreatic cancer cells involves inhibition of DNA double-strand break repair pathways.Genistein sensitizes sarcoma cells in vitro and in vivo by enhancing apoptosis and by inhibiting DSB repair pathwaysA hormone-DNA repair circuit governs the response to genotoxic insultmiR-195 enhances the radiosensitivity of colorectal cancer cells by suppressing CARM1.Personalised Medicine: Genome Maintenance Lessons Learned from Studies in Yeast as a Model Organism.The Role of the Core Non-Homologous End Joining Factors in Carcinogenesis and Cancer.DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis.Targeting DNA-PKcs increased anticancer drug sensitivity by suppressing DNA damage repair in osteosarcoma cell line MG63.Biological effects of (125)i seeds radiation on A549 lung cancer cells: G2/M arrest and enhanced cell death.Repair of radiation damage of U2OS osteosarcoma cells is related to DNA-dependent protein kinase catalytic subunit (DNA-PKcs) activity.Prognostic significance of nuclear or cytoplasmic nucleolin expression in human non-small cell lung cancer and its relationship with DNA-PKcs.Detection of early Abl kinase activation after ionizing radiation by using a peptide biosensor.Olaparib modulates DNA repair efficiency, sensitizes cervical cancer cells to cisplatin and exhibits anti-metastatic property.Interrogation of nucleotide excision repair capacity: impact on platinum-based cancer therapy.Identification of HLA ligands and T-cell epitopes for immunotherapy of lung cancer.DNA-PKcs deficiency sensitizes the human hepatoma HepG2 cells to cisplatin and 5-fluorouracil through suppression of the PI3K/Akt/NF-κB pathway.Directing the use of DDR kinase inhibitors in cancer treatment.MicroRNA-488-3p sensitizes malignant melanoma cells to cisplatin by targeting PRKDC.The relationship between p27(kip1) expression and the change of radiosensitivity of esophageal carcinoma cells.Predictive factors for the sensitivity of radiotherapy and prognosis of esophageal squamous cell carcinoma.Injection of an SV40 transcriptional terminator causes embryonic lethality: a possible zebrafish model for screening nonhomologous end-joining inhibitorsThe Relative Biological Effect of Spread-Out Bragg Peak Protons in Sensitive and Resistant Tumor CellsCombined ATR and DNA-PK Inhibition Radiosensitizes Tumor Cells Independently of Their p53 StatusTumor DNA-dependent protein kinase catalytic subunit expression is associated with hepatitis B surface antigen status and tumor progression in patients with hepatocellular carcinoma
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Radioresistant cervical cancer shows upregulation of the NHEJ proteins DNA-PKcs, Ku70 and Ku86.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 11 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Radioresistant cervical cancer ...... teins DNA-PKcs, Ku70 and Ku86.
@en
Radioresistant cervical cancer ...... teins DNA-PKcs, Ku70 and Ku86.
@nl
type
label
Radioresistant cervical cancer ...... teins DNA-PKcs, Ku70 and Ku86.
@en
Radioresistant cervical cancer ...... teins DNA-PKcs, Ku70 and Ku86.
@nl
prefLabel
Radioresistant cervical cancer ...... teins DNA-PKcs, Ku70 and Ku86.
@en
Radioresistant cervical cancer ...... teins DNA-PKcs, Ku70 and Ku86.
@nl
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Radioresistant cervical cancer ...... teins DNA-PKcs, Ku70 and Ku86.
@en
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A Holgersson
J Skikuniene
K Viktorsson
R Lewensohn
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P2888
P304
P356
10.1038/SJ.BJC.6605201
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P577
2009-08-11T00:00:00Z
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P6179
1010289878