Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53. - Wikidata - wikimedia - TriplyDB

Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.

Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.

http://www.wikidata.org/entity/Q30450287

about

Glycogen synthase kinase3 beta phosphorylates serine 33 of p53 and activates p53's transcriptional activity A role for ATR in the DNA damage-induced phosphorylation of p53 Cloning and characterization of a p53-related protein kinase expressed in interleukin-2-activated cytotoxic T-cells, epithelial tumor cell lines, and the testes Protein kinase CK2 is involved in G2 arrest and apoptosis following spindle damage in epithelial cells DNA-dependent protein kinase (DNA-PK) permits vascular smooth muscle cell proliferation through phosphorylation of the orphan nuclear receptor NOR1 DNA-dependent protein kinase phosphorylation of IkappaB alpha and IkappaB beta regulates NF-kappaB DNA binding properties Phosphorylation of the replication protein A large subunit in the Saccharomyces cerevisiae checkpoint response Autophosphorylation of p110delta phosphoinositide 3-kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivo Gene for the catalytic subunit of the human DNA-activated protein kinase maps to the site of the XRCC7 gene on chromosome 8 p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner Significant correlation of species longevity with DNA double strand break recognition but not with telomere length Biochemical evidence for Ku-independent backup pathways of NHEJ The proteasome inhibitor MG-132 sensitizes PC-3 prostate cancer cells to ionizing radiation by a DNA-PK-independent mechanism.Another fork in the road--life or death decisions by the tumour suppressor p53 Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase.The DNA-dependent protein kinase catalytic subunit phosphorylation sites in human Artemis.Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase.Artemis C-terminal region facilitates V(D)J recombination through its interactions with DNA Ligase IV and DNA-PKcs The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosis p53 Acetylation: Regulation and Consequences Substrate specificities and identification of putative substrates of ATM kinase family members Regulatory interactions between the checkpoint kinase Chk1 and the proteins of the DNA-dependent protein kinase complex Proline, glutamic acid and leucine-rich protein-1 is essential for optimal p53-mediated DNA damage response Reciprocal repression between P53 and TCTP Cisplatinum and taxol induce different patterns of p53 phosphorylation Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366 A role for c-Jun N-terminal kinase 1 (JNK1), but not JNK2, in the beta-amyloid-mediated stabilization of protein p53 and induction of the apoptotic cascade in cultured cortical neurons Oxidative stress enhances phosphorylation of p53 in neonatal rat cardiomyocytes Multiple actions of pifithrin-alpha on doxorubicin-induced apoptosis in rat myoblastic H9c2 cells Identification of DNA-dependent protein kinase as a cofactor for the forkhead transcription factor FoxA2 Comparative genetics of longevity and cancer: insights from long-lived rodents Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 signaling DNA damage activates p53 through a phosphorylation-acetylation cascade Regulation of DNA-dependent protein kinase by the Lyn tyrosine kinase.Survivin safeguards chromosome numbers and protects from aneuploidy independently from p53 ATR is a caffeine-sensitive, DNA-activated protein kinase with a substrate specificity distinct from DNA-PK.Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase.Utilization of oriented peptide libraries to identify substrate motifs selected by ATM.PKCtheta II, a new isoform of protein kinase C specifically expressed in the seminiferous tubules of mouse testis.The plant isoflavenoid genistein activates p53 and Chk2 in an ATM-dependent manner.

P2860

Q21284181-642A1FCC-5F04-4EE5-BAE8-8A604E10D5D4 Q22008733-F72E9B63-511E-42CA-8654-10B62142AF83 Q24291659-F87123B6-CB90-4078-B930-073EEDD40827 Q24291894-E49F6C1D-7628-4383-8E95-D231DD6FCB6D Q24336401-23C25D24-6451-4067-A020-12310934FBE7 Q24522560-34AE7667-B48B-42A2-9A0F-038F8C9F1BBA Q24523941-EDD3497F-A38F-4FDB-B5C1-32009364503E Q24533731-D5093D6E-F76C-4B6A-BB7D-298FB2B5DC75 Q24564348-B63E77F1-730B-4182-A4D4-A2923D5D7B64 Q24643993-D851721C-F332-401F-B9AA-E96683C8BF25 Q24653275-9BB25824-440C-4FA0-9B04-343E5E16AF9A Q24678907-FF16A809-8805-40DD-8E43-23977D2BE522 Q24813108-CA7E12B0-00F4-4DD6-AB70-7DEAECA631EF Q27026310-5E1A129F-9333-43F2-A68F-C5CE801F5E8F Q27919628-DC5E5431-3E8D-47E6-A166-1F4E93DD0322 Q27919681-F10CBBED-83D1-41A9-875D-BAE42DF83AE0 Q27930725-AD1E7750-D601-4897-BF24-D9EE6D238638 Q28000104-286ED4BD-FFDF-4DCE-9B64-46B64A19217A Q28081821-377E6167-728F-4F40-B7C4-389AFC45C578 Q28085076-8A23A556-3D18-4BD5-A417-6A3D981A1AB0 Q28141080-A3B92D84-1642-4722-B73B-06F0610A61B9 Q28205116-41675F44-AFDD-490A-9E0C-FF7702630811 Q28239216-D938D24B-41DE-44D1-8550-6CE684C0FB96 Q28255116-2DE38FB0-21ED-4BA6-B528-52BAC43AD881 Q28363906-DAD3739C-1C5E-42BF-B672-70518D7740E9 Q28504452-198EB6FB-42D6-46EC-ADA4-4FCA83F79D14 Q28573424-23D507C0-BF27-48F8-9D11-FA074F88E26B Q28573583-82AE3020-5FC0-420B-B48B-6232CE5F947B Q28577227-0AF5BA59-25EF-4A37-B90B-9DA72F16F00B Q28577792-4CF56643-A935-4D7D-B71C-E215AF1433FB Q28652609-EC90E2C3-E6DF-4B23-9F8E-11BD90123169 Q28910464-618D4A8C-6FEF-4B25-ADDE-381BBCA6B837 Q29616294-51D49286-BA1D-45D1-AB7B-4FC94F47D1B2 Q30176052-A6EC6F14-8422-4F8C-8BA7-9E0F7D6B61A2 Q30579633-9C288DF4-4CDD-40FB-9AE1-B6872724FD65 Q30585346-697F02FA-E070-4A68-A1B4-985CCF55A9E5 Q30845708-3B9B88A6-4F15-4E96-A724-3CD1F63080E8 Q30868748-00B3167E-8DA1-40EF-8E8D-4516F04792AA Q30996994-724B8BA6-A2FC-4C6E-880D-D130E00EFF66 Q31627070-EB7FB546-FF47-4C80-A431-B33BA32FD798

P2860

Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.

http://www.wikidata.org/entity/Q30450287

description

1992 nî lūn-bûn

@nan

1992 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

1992 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

1992年の論文

@ja

1992年論文

@yue

1992年論文

@zh-hant

1992年論文

@zh-hk

1992年論文

@zh-mo

1992年論文

@zh-tw

1992年论文

@wuu

name

Human DNA-activated protein ki ...... ctivation domain of human p53.

@ast

Human DNA-activated protein ki ...... ctivation domain of human p53.

@en

type

label

Human DNA-activated protein ki ...... ctivation domain of human p53.

@ast

Human DNA-activated protein ki ...... ctivation domain of human p53.

@en

prefLabel

Human DNA-activated protein ki ...... ctivation domain of human p53.

@ast

Human DNA-activated protein ki ...... ctivation domain of human p53.

@en

P1433

Q30450287-4144A011-BCF0-4F57-9863-FC2A0E889783

P1476

Q30450287-0E8707EB-746A-4ABF-BC81-3D7D055B1BD7

P2093

Q30450287-2F22D1D6-8E12-41F3-AB05-89AA8D2F7E43

Q30450287-3A379299-1F0E-4A34-B76B-ADC8D243126E

Q30450287-670B3CC7-AD43-4518-A38D-3292C29F3282

Q30450287-6DDA2937-09F0-4F9B-BC47-2766EEDBA92D

Q30450287-D235DF13-2296-455F-96B0-A3AA7DD2DDE4

P2860

Q30450287-02E4D91E-6253-4506-B599-DA55DFCF2FB5

Q30450287-0376DDFE-2F88-42C8-B6EA-E6586B44BB69

Q30450287-0685CD87-D64B-4513-BDBE-9CABD25D5119

Q30450287-0DDEB388-5425-420A-8DC8-CDEEB04006BA

Q30450287-1C7C7C7D-E69D-41F2-BF30-1A151CFDBEF2

Q30450287-1F59ECA4-347E-4B66-BB12-647832639C6A

Q30450287-2BE063D2-D4D4-4CE0-B3A9-DFF7A1A123B0

Q30450287-2C1F439B-85D3-4D36-8BD9-5EC7D8D6CC5A

Q30450287-2E0E0C4C-B2F0-4BDB-848B-AE90E1169FBE

Q30450287-33032A63-758E-4DD0-A53D-C5E4B47FA628

P304

Q30450287-9288720B-1C3E-4C9F-8B9D-D789D8210620

P31

Q30450287-D9FE7C8C-872E-4294-B868-71840A3A1BC4

P356

Q30450287-4917296F-0FDE-4238-A2DD-9C4ECBAE4566

P407

Q30450287-3ACE0982-0B34-492D-8FCC-CA88F794C234

P433

Q30450287-A5712006-F492-4863-A6DD-CC5A6BC244D4

P478

Q30450287-DA8CB383-502F-4C73-9D45-D8E4B6D78FAD

P577

Q30450287-61C3C8C5-EA6C-4740-84D8-5883F880976F

P698

Q30450287-60B3055B-F2A6-47E2-9D65-6A114A2AE469

P921

Q30450287-0BC297F6-1A72-4D9E-B6C3-8CAEBC06EB8E

P932

Q30450287-56A4B951-7918-4A29-A58E-985AFFB22E76

P356

P1433

Molecular and Cellular Biology

P1476

Human DNA-activated protein ki ...... ctivation domain of human p53.

@en

P2093

Anderson CW

http://www.w3.org/2001/XMLSchema#string

Appella E

http://www.w3.org/2001/XMLSchema#string

Lees-Miller SP

http://www.w3.org/2001/XMLSchema#string

Sakaguchi K

http://www.w3.org/2001/XMLSchema#string

Ullrich SJ

http://www.w3.org/2001/XMLSchema#string

P2860

Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene

Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase

Human p53 cellular tumor antigen: cDNA sequence and expression in COS cells

A DNA-activated protein kinase from HeLa cell nuclei

Identification of p53 as a sequence-specific DNA-binding protein

Phosphate groups as substrate determinants for casein kinase I action

Protein kinase phosphorylation site sequences and consensus specificity motifs: tabulations

Suppression of human colorectal carcinoma cell growth by wild-type p53

Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2

Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.

P304

5041-5049

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1128/MCB.12.11.5041

http://www.w3.org/2001/XMLSchema#string

P407

P433

11

http://www.w3.org/2001/XMLSchema#string

P478

12

http://www.w3.org/2001/XMLSchema#string

P577

1992-11-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

1406679

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation

P932

360437

http://www.w3.org/2001/XMLSchema#string