RNA interference-mediated silencing of the respiratory syncytial virus nucleocapsid defines a potent antiviral strategy.
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Respiratory Syncytial Virus (RSV) Modulation at the Virus-Host Interface Affects Immune Outcome and Disease PathogenesisInduction of protective effector immunity to prevent pathogenesis caused by the respiratory syncytial virus. Implications on therapy and vaccine designHuman metapneumovirus in adultsDelivery of RNAi Therapeutics to the Airways-From Bench to BedsideMicroRNA regulation of human protease genes essential for influenza virus replicationMicroRNA Regulation of Human Genes Essential for Influenza A (H7N9) ReplicationHuman RGM249-derived small RNAs potentially regulate tumor malignancySilencing disease genes in the laboratory and the clinicEvidence of RNAi in humans from systemically administered siRNA via targeted nanoparticlesAdvances in antivirals for non-influenza respiratory virus infections.Drug delivery-mediated control of RNA immunostimulationPharmacologic advances in the treatment and prevention of respiratory syncytial virus.Reduced Dicer expression in the cord blood of infants admitted with severe respiratory syncytial virus disease.Clinical status of duplex RNAA randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus.A status report on RNAi therapeutics.Inhibition of Tulane virus replication in vitro with RNA interference.Optimizing siRNA delivery to the genital mucosasiRNA-based topical microbicides targeting sexually transmitted infections.Current progress of siRNA/shRNA therapeutics in clinical trials.Oxime ether lipids containing hydroxylated head groups are more superior siRNA delivery agents than their nonhydroxylated counterparts.Aerosol Delivery of siRNA to the Lungs. Part 2: Nanocarrier-based Delivery SystemsInhibition of HCV 5'-NTR and core expression by a small hairpin RNA delivered by a histone gene carrier, HPhA.Exploiting endocytosis for nanomedicines.Targeting RSV with vaccines and small molecule drugs.Recent advances in diagnosis, prevention, and treatment of human respiratory syncytial virus.Silencing sexually transmitted infections: topical siRNA-based interventions for the prevention of HIV and HSVLipid-based nanotherapeutics for siRNA deliveryPotential clinical applications of siRNA technique: benefits and limitations.RNA-based therapeutics: current progress and future prospects.Expert opinion in biological therapy: update on developments in lung gene transfer.Delivery systems and local administration routes for therapeutic siRNA.Platelet Activating Factor Receptor Activation Improves siRNA Uptake and RNAi Responses in Well-differentiated Airway Epithelia.Clinical translation of RNAi-based treatments for respiratory diseases.Respiratory syncytial virus: prospects for new and emerging therapeutics.Recent Advances in Developing Antiviral Therapies for Respiratory Syncytial Virus.Polymers in the Delivery of siRNA for the Treatment of Virus Infections.Respiratory syncytial virus modifies microRNAs regulating host genes that affect virus replication.Direct whole-genome deep-sequencing of human respiratory syncytial virus A and B from Vietnamese children identifies distinct patterns of inter- and intra-host evolution.The potential of anti-infectives and immunomodulators as therapies for asthma and asthma exacerbations.
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P2860
RNA interference-mediated silencing of the respiratory syncytial virus nucleocapsid defines a potent antiviral strategy.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 08 June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
RNA interference-mediated sile ...... s a potent antiviral strategy.
@en
RNA interference-mediated sile ...... s a potent antiviral strategy.
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type
label
RNA interference-mediated sile ...... s a potent antiviral strategy.
@en
RNA interference-mediated sile ...... s a potent antiviral strategy.
@nl
prefLabel
RNA interference-mediated sile ...... s a potent antiviral strategy.
@en
RNA interference-mediated sile ...... s a potent antiviral strategy.
@nl
P2093
P2860
P356
P1476
RNA interference-mediated sile ...... s a potent antiviral strategy.
@en
P2093
Ingo Roehl
Ivanka Toudjarska
Jeffrey Kahn
John P DeVincenzo
Lubomir Nechev
Mark Van Ranst
Martin Maier
Mathias John
Muthiah Manoharan
Philipp Hadwiger
P2860
P304
P356
10.1128/AAC.00014-09
P407
P577
2009-06-08T00:00:00Z