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MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCMStructural peculiarities of the (MHF1-MHF2)4 octamer provide a long DNA binding patch to anchor the MHF-FANCM complex to chromatin: a solution SAXS studyDNA polymerase POLN participates in cross-link repair and homologous recombinationFanconi anemia complementation group A (FANCA) protein has intrinsic affinity for nucleic acids with preference for single-stranded formsHow the fanconi anemia pathway guards the genomePhenotypes and genotypes of the chromosomal instability syndromesThe Fanconi anemia pathway and DNA interstrand cross-link repairLearning from a paradox: recent insights into Fanconi anaemia through studying mouse modelsDiagnosis of Fanconi Anemia: Chromosomal Breakage AnalysisThe structure of the FANCM–MHF complex reveals physical features for functional assemblyFancf-deficient mice are prone to develop ovarian tumoursFANCI protein binds to DNA and interacts with FANCD2 to recognize branched structuresFunctional Significance of Nuclear α Spectrin.Frequency and natural history of inherited bone marrow failure syndromes: the Israeli Inherited Bone Marrow Failure Registry.Late graft failure in FA--case report and review of the literature.DNA interstrand crosslink repair in mammalian cells: step by step.Whole exome sequencing reveals concomitant mutations of multiple FA genes in individual Fanconi anemia patients.Knockdown of mu-calpain in Fanconi anemia, FA-A, cells by siRNA restores alphaII spectrin levels and corrects chromosomal instability and defective DNA interstrand cross-link repair.The Fanconi anemia protein, FANCG, binds to the ERCC1-XPF endonuclease via its tetratricopeptide repeats and the central domain of ERCC1.Direct inhibition of TNF-α promoter activity by Fanconi anemia protein FANCD2.G-quadruplex nucleic acids and human diseaseCoregulation of FANCA and BRCA1 in human cellsp38 MAPK inhibition suppresses the TLR-hypersensitive phenotype in FANCC- and FANCA-deficient mononuclear phagocytesKIAA1018/FAN1 nuclease protects cells against genomic instability induced by interstrand cross-linking agents.PALB2/FANCN: recombining cancer and Fanconi anemia.Correct mRNA processing at a mutant TT splice donor in FANCC ameliorates the clinical phenotype in patients and is enhanced by delivery of suppressor U1 snRNAs.DNA repair deficiency in neurodegeneration.Human FANCC is hypomorphic in murine Fancc-deficient cellsFormaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway.Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia.Cytoplasmic FANCA-FANCC complex interacts and stabilizes the cytoplasm-dislocalized leukemic nucleophosmin protein (NPMc)Deficiencies in the Fanconi anemia DNA damage response pathway increase sensitivity to HPV-associated head and neck cancerSpontaneous abrogation of the G₂DNA damage checkpoint has clinical benefits but promotes leukemogenesis in Fanconi anemia patients.RAD51C--a new human cancer susceptibility gene for sporadic squamous cell carcinoma of the head and neck (HNSCC).Global and disease-associated genetic variation in the human Fanconi anemia gene family.DNA-bound platinum is the major determinant of cisplatin sensitivity in head and neck squamous carcinoma cells.The Fanconi anemia pathway and ICL repair: implications for cancer therapy.Human Fanconi anemia complementation group a protein stimulates the 5' flap endonuclease activity of FEN1.Development of primary early-onset colorectal cancers due to biallelic mutations of the FANCD1/BRCA2 geneA case report and literature review of Fanconi Anemia (FA) diagnosed by genetic testing.
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
The genetic and molecular basis of Fanconi anemia.
@en
The genetic and molecular basis of Fanconi anemia.
@nl
type
label
The genetic and molecular basis of Fanconi anemia.
@en
The genetic and molecular basis of Fanconi anemia.
@nl
prefLabel
The genetic and molecular basis of Fanconi anemia.
@en
The genetic and molecular basis of Fanconi anemia.
@nl
P1433
P1476
The genetic and molecular basis of Fanconi anemia.
@en
P2093
Hans Joenje
Johan P de Winter
P356
10.1016/J.MRFMMM.2008.11.004
P407
P577
2008-11-14T00:00:00Z