Dedicator of cytokinesis 8 interacts with talin and Wiskott-Aldrich syndrome protein to regulate NK cell cytotoxicity.
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Lytic immune synapse function requires filamentous actin deconstruction by Coronin 1ACOMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7ACell biological steps and checkpoints in accessing NK cell cytotoxicityMolecular mechanisms and functional implications of polarized actin remodeling at the T cell immunological synapseCoactosin-like 1 antagonizes cofilin to promote lamellipodial protrusion at the immune synapseDOCK8 regulates lymphocyte shape integrity for skin antiviral immunityA DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton.DOCK8 regulates signal transduction events to control immunityDOCK8 regulates protective immunity by controlling the function and survival of RORγt+ ILCsSNX17 affects T cell activation by regulating TCR and integrin recyclingHkRP3 is a microtubule-binding protein regulating lytic granule clustering and NK cell killing.Hypomorphic function and somatic reversion of DOCK8 cause combined immunodeficiency without hyper-IgERecent Advances in DOCK8 Immunodeficiency Syndrome.Human immunodeficiency syndromes affecting human natural killer cell cytolytic activity.Dock protein family in brain development and neurological disease.The central role of the cytoskeleton in mechanisms and functions of the NK cell immune synapse.DOCK8 deficiency: clinical and immunological phenotype and treatment options - a review of 136 patients.Insights into primary immune deficiency from quantitative microscopy.Origins of the cytolytic synapse.MMSET is dynamically regulated during cell-cycle progression and promotes normal DNA replication.Current Status of Dedicator of Cytokinesis-Associated Immunodeficiency: DOCK8 and DOCK2.The clinical and laboratory spectrum of dedicator of cytokinesis 8 immunodeficiency syndrome in patients with a unique mutation.Molecular stretching modulates mechanosensing pathways.DOCK8 deficiency: Insights into pathophysiology, clinical features and management.Quantitative Imaging Approaches to Study the CAR Immunological Synapse.DOCK8 Drives Src-Dependent NK Cell Effector Function.Dedicator of cytokinesis 8 regulates signal transducer and activator of transcription 3 activation and promotes TH17 cell differentiation.Novel DOCK8 gene mutations lead to absence of protein expression in patients with hyper-IgE syndrome.Key findings to expedite the diagnosis of hyper-IgE syndromes in infants and young children.Mutations in PI3K110δ cause impaired NK cell function partially rescued by rapamycin treatment.DOCK8 Deficiency Presenting as an IPEX-Like Disorder.DOCK8 enforces immunological tolerance by promoting IL-2 signaling and immune synapse formation in Tregs.DOCK8: regulator of Treg in response to corticotropin-releasing hormone.A novel Dock8 gene mutation confers diabetogenic susceptibility in the LEW.1AR1/Ztm-iddm rat, an animal model of human type 1 diabetes.WASP-mediated regulation of anti-inflammatory macrophages is IL-10 dependent and is critical for intestinal homeostasis.Interaction of septin 7 and DOCK8 in equine lymphocytes reveals novel insights into signaling pathways associated with autoimmunity
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Dedicator of cytokinesis 8 interacts with talin and Wiskott-Aldrich syndrome protein to regulate NK cell cytotoxicity.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on March 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Dedicator of cytokinesis 8 int ...... regulate NK cell cytotoxicity.
@en
Dedicator of cytokinesis 8 int ...... regulate NK cell cytotoxicity.
@nl
type
label
Dedicator of cytokinesis 8 int ...... regulate NK cell cytotoxicity.
@en
Dedicator of cytokinesis 8 int ...... regulate NK cell cytotoxicity.
@nl
prefLabel
Dedicator of cytokinesis 8 int ...... regulate NK cell cytotoxicity.
@en
Dedicator of cytokinesis 8 int ...... regulate NK cell cytotoxicity.
@nl
P2093
P2860
P356
P1476
Dedicator of cytokinesis 8 int ...... regulate NK cell cytotoxicity.
@en
P2093
Daniel D Billadeau
Erik L Anderson
Hyoungjun Ham
JungJin Kim
Michael J Hamann
Renee A Schoon
Sabrice Guerrier
Zhenkun Lou
P2860
P304
P356
10.4049/JIMMUNOL.1202792
P407
P577
2013-03-01T00:00:00Z