Role of MAPK kinase 6 in arthritis: distinct mechanism of action in inflammation and cytokine expression. - Wikidata - wikimedia - TriplyDB

Role of MAPK kinase 6 in arthritis: distinct mechanism of action in inflammation and cytokine expression.

Role of MAPK kinase 6 in arthritis: distinct mechanism of action in inflammation and cytokine expression.

http://www.wikidata.org/entity/Q37348061

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Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis Cellular targeting in autoimmunity Overexpression of Ste20-related proline/alanine-rich kinase exacerbates experimental colitis in mice Differential roles of MAPK kinases MKK3 and MKK6 in osteoclastogenesis and bone loss.Differential regulation of anti-inflammatory genes by p38 MAP kinase and MAP kinase kinase 6.Germinal center kinase-like kinase (GLK/MAP4K3) expression is increased in adult-onset Still's disease and may act as an activity marker.Decreased collagen-induced arthritis severity and adaptive immunity in MKK-6-deficient mice.Antiinflammatory functions of p38 in mouse models of rheumatoid arthritis: advantages of targeting upstream kinases MKK-3 or MKK-6 Selective Regulation of MAPK Signaling Mediates RANKL-dependent Osteoclast Differentiation.Recent advances in neutralizing the IL-6 pathway in arthritis."Go upstream, young man": lessons learned from the p38 saga.The p38 MAPK Pathway in Rheumatoid Arthritis: A Sideways Look.Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors.Monocytic cell differentiation from band-stage neutrophils under inflammatory conditions via MKK6 activation.Roles of p38α mitogen-activated protein kinase in mouse models of inflammatory diseases and cancer.Correlation between cold and hot pattern in traditional Chinese medicine and gene expression profiles in rheumatoid arthritis.Identification of potential peripheral blood diagnostic biomarkers for patients with juvenile idiopathic arthritis by bioinformatics analysis.A de novo 1.58 Mb deletion, including MAP2K6 and mapping 1.28 Mb upstream to SOX9, identified in a patient with Pierre Robin sequence and osteopenia with multiple fractures.The discoidin domain receptor 2/annexin A2/matrix metalloproteinase 13 loop promotes joint destruction in arthritis through promoting migration and invasion of fibroblast-like synoviocytes.Alternative p38 MAPKs are essential for collagen-induced arthritis.

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Role of MAPK kinase 6 in arthritis: distinct mechanism of action in inflammation and cytokine expression.

http://www.wikidata.org/entity/Q37348061

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 26 June 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Role of MAPK kinase 6 in arthr ...... ation and cytokine expression.

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Role of MAPK kinase 6 in arthr ...... ation and cytokine expression.

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type

label

Role of MAPK kinase 6 in arthr ...... ation and cytokine expression.

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Role of MAPK kinase 6 in arthr ...... ation and cytokine expression.

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prefLabel

Role of MAPK kinase 6 in arthr ...... ation and cytokine expression.

@en

Role of MAPK kinase 6 in arthr ...... ation and cytokine expression.

@nl

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JIMMUNOL.0900483

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Journal of Immunology

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Role of MAPK kinase 6 in arthr ...... ation and cytokine expression.

@en

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David L Boyle

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Deepa Hammaker

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Gary S Firestein

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Maripat Corr

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Richard Flavell

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Roger Davis

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Toshio Yoshizawa

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Crystal structure of the p38 alpha-MAPKAP kinase 2 heterodimer

Leptomycin B-sensitive nuclear export of MAPKAP kinase 2 is regulated by phosphorylation

Quantitative biomarker analysis of synovial gene expression by real-time PCR

Strong inhibition of TNF-alpha production and inhibition of IL-8 and COX-2 mRNA expression in monocyte-derived macrophages by RWJ 67657, a p38 mitogen-activated protein kinase (MAPK) inhibitor

Structure of mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 suggests a bifunctional switch that couples kinase activation with nuclear export

Molecular basis of MAPK-activated protein kinase 2:p38 assembly

Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: scaffold role of Pbs2p MAPKK.

Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression

MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels

MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis

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1360-1367

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scholarly article

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10.4049/JIMMUNOL.0900483

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2009-06-26T00:00:00Z

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