A genetic variant of Aurora kinase A promotes genomic instability leading to highly malignant skin tumors.

A genetic variant of Aurora kinase A promotes genomic instability leading to highly malignant skin tumors.

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http://www.wikidata.org/entity/Q37350394
Functional Significance of Aurora Kinases-p53 Protein Family Interactions in CancerDefects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin IchthyosisAurora kinase-A deficiency during skin development impairs cell division and stratificationA novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myelomaOverexpression of Aurora-A promotes laryngeal cancer progression by enhancing invasive ability and chromosomal instabilityMyc, Aurora Kinase A, and mutant p53(R172H) co-operate in a mouse model of metastatic skin carcinoma.Possibility of the use of public microarray database for identifying significant genes associated with oral squamous cell carcinomaAssessment of the in vivo antitumor effects of ENMD-2076, a novel multitargeted kinase inhibitor, against primary and cell line-derived human colorectal cancer xenograft models.Cell cycle proteins as promising targets in cancer therapyAurora kinase-A overexpression in mouse mammary epithelium induces mammary adenocarcinomas harboring genetic alterations shared with human breast cancer.Low concentration of arsenic-induced aberrant mitosis in keratinocytes through E2F1 transcriptionally regulated Aurora-A.Clinical Development of Anti-mitotic Drugs in Cancer.p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation
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A genetic variant of Aurora kinase A promotes genomic instability leading to highly malignant skin tumors.

Item
http://www.wikidata.org/entity/Q37350394
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 08 September 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A genetic variant of Aurora ki ...... highly malignant skin tumors.
@en
A genetic variant of Aurora ki ...... highly malignant skin tumors.
@nl
type
label
A genetic variant of Aurora ki ...... highly malignant skin tumors.
@en
A genetic variant of Aurora ki ...... highly malignant skin tumors.
@nl
prefLabel
A genetic variant of Aurora ki ...... highly malignant skin tumors.
@en
A genetic variant of Aurora ki ...... highly malignant skin tumors.
@nl
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A genetic variant of Aurora ki ...... highly malignant skin tumors.
@en
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P2860
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10.1158/0008-5472.CAN-09-1059
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P698
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