Unifying theory of hypoxia tolerance: molecular/metabolic defense and rescue mechanisms for surviving oxygen lack.
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Metabolic rate depression in animals: transcriptional and translational controlsDifferential activities of murine single minded 1 (SIM1) and SIM2 on a hypoxic response element. Cross-talk between basic helix-loop-helix/per-Arnt-Sim homology transcription factorsRegulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha.Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cellsForever young: mechanisms of natural anoxia tolerance and potential links to longevityHibernating without oxygen: physiological adaptations of the painted turtleMutation in mitochondrial complex I ND6 subunit is associated with defective response to hypoxia in human glioma cellsOxygen-sensing mechanisms and the regulation of redox-responsive transcription factors in development and pathophysiologyExpression profiling of laser-microdissected intrapulmonary arteries in hypoxia-induced pulmonary hypertensionCharacterization of sub-nuclear changes in Caenorhabditis elegans embryos exposed to brief, intermediate and long-term anoxia to analyze anoxia-induced cell cycle arrestHypoxic stress suppresses RNA polymerase III recruitment and tRNA gene transcription in cardiomyocytes."Oxygen Sensing" by Na,K-ATPase: These Miraculous ThiolsA unifying theory for general multigenic heterosis: energy efficiency, protein metabolism, and implications for molecular breedingHypoxia and metabolic properties of hematopoietic stem cellsUltrastructural modifications in the mitochondria of hypoxia-adapted Drosophila melanogasterHypoxia impairs primordial germ cell migration in zebrafish (Danio rerio) embryosEnvironmental and genetic preconditioning for long-term anoxia responses requires AMPK in Caenorhabditis elegansDiaphragm Muscle Adaptation to Sustained Hypoxia: Lessons from Animal Models with Relevance to High Altitude and Chronic Respiratory DiseasesMolecular Connections between Cancer Cell Metabolism and the Tumor MicroenvironmentCounterpoint: positive effects of intermittent hypoxia (live high:train low) on exercise performance are not mediated primarily by augmented red cell volumeThe re-establishment of the normal blood lactate response to exercise in humans after prolonged acclimatization to altitudeMetabolic profiling of hypoxic cells revealed a catabolic signature required for cell survivalHypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3.Shared Genetic Signals of Hypoxia Adaptation in Drosophila and in High-Altitude Human PopulationsOverexpression of fructose 2,6-bisphosphatase decreases glycolysis and delays cell cycle progressionBiochemistry and evolution of anaerobic energy metabolism in eukaryotesPAS domains: internal sensors of oxygen, redox potential, and lightDifferential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulationSubcellular Energetics and Metabolism: A Cross-Species Framework.Reduction in ovulation or male sex phenotype increases long-term anoxia survival in a daf-16-independent manner in Caenorhabditis elegans.Proteomic analysis of anoxia tolerance in the developing zebrafish embryo.The zebrafish embryo as a dynamic model of anoxia tolerance.Use of culture geometry to control hypoxia-induced vascular endothelial growth factor secretion from adipose-derived stem cells: optimizing a cell-based approach to drive vascular growthLiving in the cold: freeze-induced gene responses in freeze-tolerant vertebrates.Flexibility in metabolic rate confers a growth advantage under changing food availability.Functional genomics approach to hypoxia signaling.Analysis of beta-cell gene expression reveals inflammatory signaling and evidence of dedifferentiation following human islet isolation and cultureExposure of yeast cells to anoxia induces transient oxidative stress. Implications for the induction of hypoxic genes.Induction of adrenomedullin during hypoxia in cultured human glioblastoma cells.Adenosine mediates decreased cerebral metabolic rate and increased cerebral blood flow during acute moderate hypoxia in the near-term fetal sheep.
P2860
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P2860
Unifying theory of hypoxia tolerance: molecular/metabolic defense and rescue mechanisms for surviving oxygen lack.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Unifying theory of hypoxia tol ...... sms for surviving oxygen lack.
@en
Unifying theory of hypoxia tol ...... sms for surviving oxygen lack.
@nl
type
label
Unifying theory of hypoxia tol ...... sms for surviving oxygen lack.
@en
Unifying theory of hypoxia tol ...... sms for surviving oxygen lack.
@nl
prefLabel
Unifying theory of hypoxia tol ...... sms for surviving oxygen lack.
@en
Unifying theory of hypoxia tol ...... sms for surviving oxygen lack.
@nl
P2093
P2860
P356
P1476
Unifying theory of hypoxia tol ...... isms for surviving oxygen lack
@en
P2093
P2860
P304
P356
10.1073/PNAS.93.18.9493
P407
P577
1996-09-01T00:00:00Z