Leptin promotes epithelial-mesenchymal transition of breast cancer via the upregulation of pyruvate kinase M2.
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Collagen triple helix repeat containing-1 negatively regulated by microRNA-30c promotes cell proliferation and metastasis and indicates poor prognosis in breast cancer.Leptin-induced migration and angiogenesis in rheumatoid arthritis is mediated by reactive oxygen species.Manganese-12 acetate suppresses the migration, invasion, and epithelial-mesenchymal transition by inhibiting Wnt/β-catenin and PI3K/AKT signaling pathways in breast cancer cells.Leptin regulation of the p53-HIF1α/PKM2-aromatase axis in breast adipose stromal cells-a novel mechanism for the obesity-breast cancer link.Leptin-induced ER-α-positive breast cancer cell viability and migration is mediated by suppressing CCN5-signaling via activating JAK/AKT/STAT-pathway.Leptin Signaling Mediates Obesity-associated CSC Enrichment and EMT in Preclinical TNBC Models.Inflammatory interferon activates HIF-1α-mediated epithelial-to-mesenchymal transition via PI3K/AKT/mTOR pathway.
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Leptin promotes epithelial-mesenchymal transition of breast cancer via the upregulation of pyruvate kinase M2.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 21 October 2016
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Leptin promotes epithelial-mes ...... ulation of pyruvate kinase M2.
@en
Leptin promotes epithelial-mes ...... ulation of pyruvate kinase M2.
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type
label
Leptin promotes epithelial-mes ...... ulation of pyruvate kinase M2.
@en
Leptin promotes epithelial-mes ...... ulation of pyruvate kinase M2.
@nl
prefLabel
Leptin promotes epithelial-mes ...... ulation of pyruvate kinase M2.
@en
Leptin promotes epithelial-mes ...... ulation of pyruvate kinase M2.
@nl
P2093
P2860
P1476
Leptin promotes epithelial-mes ...... ulation of pyruvate kinase M2.
@en
P2093
Bianqin Guo
Changli Zhong
Junhong Yang
Kuangfa Li
Tingmei Chen
Xueli Pang
P2860
P2888
P356
10.1186/S13046-016-0446-4
P577
2016-10-21T00:00:00Z
P6179
1039977866