Purification and architecture of the ubiquitous Wave complex. - Wikidata - wikimedia - TriplyDB

Purification and architecture of the ubiquitous Wave complex.

Purification and architecture of the ubiquitous Wave complex.

http://www.wikidata.org/entity/Q37357529

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The WASP and WAVE family proteins Inclusion of Scar/WAVE3 in a similar complex to Scar/WAVE1 and 2 The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis NESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylation A FAM21-containing WASH complex regulates retromer-dependent sorting Free Brick1 is a trimeric precursor in the assembly of a functional wave complex The Cdc42 effector IRSp53 generates filopodia by coupling membrane protrusion with actin dynamics WW domains provide a platform for the assembly of multiprotein networks Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contexts Bcr-Abl induces abnormal cytoskeleton remodeling, beta1 integrin clustering and increased cell adhesion to fibronectin through the Abl interactor 1 pathway Phosphoregulation of the WAVE regulatory complex and signal integration Under lock and key: spatiotemporal regulation of WASP family proteins coordinates separate dynamic cellular processes Differential regulation of macropinocytosis by Abi1/Hssh3bp1 isoforms Requirements for F-BAR proteins TOCA-1 and TOCA-2 in actin dynamics and membrane trafficking during Caenorhabditis elegans oocyte growth and embryonic epidermal morphogenesis High-Resolution X-Ray Structure of the Trimeric Scar/WAVE-Complex Precursor Brk1 Role of the WASP and WAVE family proteins in breast cancer invasion and metastasis Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation WAVE3-mediated cell migration and lamellipodia formation are regulated downstream of phosphatidylinositol 3-kinase WAVE1 and regulation of actin nucleation in myelination A nucleator arms race: cellular control of actin assembly Reciprocal regulation of Abl kinase by Crk Y251 and Abi1 controls invasive phenotypes in glioblastoma.The NESH/Abi-3-based WAVE2 complex is functionally distinct from the Abi-1-based WAVE2 complex.Functional mechanisms and roles of adaptor proteins in abl-regulated cytoskeletal actin dynamics.Physical mechanisms of signal integration by WASP family proteins.Membrane targeting of WAVE2 is not sufficient for WAVE2-dependent actin polymerization: a role for IRSp53 in mediating the interaction between Rac and WAVE2.Dysbindin-containing complexes and their proposed functions in brain: from zero to (too) many in a decade.The WAVE2 complex regulates actin cytoskeletal reorganization and CRAC-mediated calcium entry during T cell activation.The N-terminus of Dictyostelium Scar interacts with Abi and HSPC300 and is essential for proper regulation and function.Optimization of WAVE2 complex-induced actin polymerization by membrane-bound IRSp53, PIP(3), and Rac.Arp2/3 complex interactions and actin network turnover in lamellipodia.Loss of Dictyostelium HSPC300 causes a scar-like phenotype and loss of SCAR protein.Phosphorylation of WAVE2 by MAP kinases regulates persistent cell migration and polarity.WAVE forms hetero- and homo-oligomeric complexes at integrin junctions in Drosophila visualized by bimolecular fluorescence complementation.Essential role for Abi1 in embryonic survival and WAVE2 complex integrity Nap1-regulated neuronal cytoskeletal dynamics is essential for the final differentiation of neurons in cerebral cortex The Drosophila Arf1 homologue Arf79F is essential for lamellipodium formation.Abi is required for modulation and stability but not localization or activation of the SCAR/WAVE complex The distinct roles of Ras and Rac in PI 3-kinase-dependent protrusion during EGF-stimulated cell migration Activation of the WAVE complex by coincident signals controls actin assembly.

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Purification and architecture of the ubiquitous Wave complex.

http://www.wikidata.org/entity/Q37357529

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 19 March 2004

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Purification and architecture of the ubiquitous Wave complex.

@en

Purification and architecture of the ubiquitous Wave complex.

@nl

type

label

Purification and architecture of the ubiquitous Wave complex.

@en

Purification and architecture of the ubiquitous Wave complex.

@nl

prefLabel

Purification and architecture of the ubiquitous Wave complex.

@en

Purification and architecture of the ubiquitous Wave complex.

@nl

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PNAS.0400628101

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Proceedings of the National Academy of Sciences of the United States of America

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Purification and architecture of the ubiquitous Wave complex.

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P2093

Hanno Steen

http://www.w3.org/2001/XMLSchema#string

Hsin-yi H Ho

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Jiaxu Li

http://www.w3.org/2001/XMLSchema#string

Marc W Kirschner

http://www.w3.org/2001/XMLSchema#string

P2860

WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac

Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex

IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling

Identification of a candidate human spectrin Src homology 3 domain-binding protein suggests a general mechanism of association of tyrosine kinases with the spectrin-based membrane skeleton

Crystal structure of Arp2/3 complex

Cellular motility driven by assembly and disassembly of actin filaments

Rho GTPases in cell biology

Correlation between protein and mRNA abundance in yeast

The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling

Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck

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4379-4383

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scholarly article

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10.1073/PNAS.0400628101

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13

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101

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Alexis Gautreau

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2004-03-19T00:00:00Z

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15070726

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384755

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