Islet beta-cells deficient in Bcl-xL develop but are abnormally sensitive to apoptotic stimuli. - Wikidata - wikimedia - TriplyDB

Islet beta-cells deficient in Bcl-xL develop but are abnormally sensitive to apoptotic stimuli.

Islet beta-cells deficient in Bcl-xL develop but are abnormally sensitive to apoptotic stimuli.

http://www.wikidata.org/entity/Q37360475

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Specific silencing of the REST target genes in insulin-secreting cells uncovers their participation in beta cell survival Mcl-1 downregulation by pro-inflammatory cytokines and palmitate is an early event contributing to β-cell apoptosis p53 up-regulated modulator of apoptosis (PUMA) activation contributes to pancreatic beta-cell apoptosis induced by proinflammatory cytokines and endoplasmic reticulum stress The Effect of Glucose Fluctuation on Apoptosis and Function of INS-1 Pancreatic Beta Cells Glucose induces pancreatic islet cell apoptosis that requires the BH3-only proteins Bim and Puma and multi-BH domain protein Bax.Protective effects of a nicotinamide derivative, isonicotinamide, against streptozotocin-induced β-cell damage and diabetes in mice The transcription factor Myt3 acts as a pro-survival factor in β-cells Group VIA Phospholipase A2 (iPLA2β) Modulates Bcl-x 5'-Splice Site Selection and Suppresses Anti-apoptotic Bcl-x(L) in β-Cells.Ginsenoside Rg1 ameliorates oxidative stress and myocardial apoptosis in streptozotocin-induced diabetic rats.Calcium-independent phospholipases A2 and their roles in biological processes and diseases.C/EBP homologous protein contributes to cytokine-induced pro-inflammatory responses and apoptosis in β-cells.Protective effect of Salacia oblonga against tobacco smoke-induced DNA damage and cellular changes in pancreatic β-cells.Carbamylated erythropoietin attenuates cardiomyopathy via PI3K/Akt activation in rats with diabetic cardiomyopathy.Bcl-2 and Bcl-xL suppress glucose signaling in pancreatic β-cells Dual Trade of Bcl-2 and Bcl-xL in islet physiology: balancing life and death with metabolism secretion coupling.Otubain 2 is a novel promoter of beta cell survival as revealed by siRNA high-throughput screens of human pancreatic islets.Mouse insulin cells expressing an inducible RIPCre transgene are functionally impaired.Expression of Pro- and Antiapoptotic Molecules of the Bcl-2 Family in Human Islets Postisolation Pancreatic β-cells activate a JunB/ATF3-dependent survival pathway during inflammation

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Islet beta-cells deficient in Bcl-xL develop but are abnormally sensitive to apoptotic stimuli.

http://www.wikidata.org/entity/Q37360475

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 06 July 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Islet beta-cells deficient in ...... ensitive to apoptotic stimuli.

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Islet beta-cells deficient in ...... ensitive to apoptotic stimuli.

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Islet beta-cells deficient in ...... ensitive to apoptotic stimuli.

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Islet beta-cells deficient in ...... ensitive to apoptotic stimuli.

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Islet beta-cells deficient in ...... ensitive to apoptotic stimuli.

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Islet beta-cells deficient in ...... ensitive to apoptotic stimuli.

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Islet beta-cells deficient in ...... ensitive to apoptotic stimuli.

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Cameron Kos

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Clare L Scott

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Elisa Jansen

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Emma M Carrington

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Janette Allison

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Mark D McKenzie

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Michelle Myers

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Stacey Fynch

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Thomas W Kay

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P2860

Tissue- and site-specific DNA recombination in transgenic mice

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.

Genetic ablation of Bcl-x attenuates invasiveness without affecting apoptosis or tumor growth in a mouse model of pancreatic neuroendocrine cancer

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

Bcl-x and Bax regulate mouse primordial germ cell survival and apoptosis during embryogenesis

Bax and Bcl-xs are induced at the onset of apoptosis in involuting mammary epithelial cells

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

Disappearance of the lymphoid system in Bcl-2 homozygous mutant chimeric mice

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

Conditional deletion of the Bcl-x gene from erythroid cells results in hemolytic anemia and profound splenomegaly.

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2316-2323

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scholarly article

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10.2337/DB08-1602

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10

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58

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Andreas Strasser

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2009-07-06T00:00:00Z

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26651229

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19581414

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apoptotic process

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2750233

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