Modulation of phosphodiesterase6 turnoff during background illumination in mouse rod photoreceptors. - Wikidata - wikimedia - TriplyDB

Modulation of phosphodiesterase6 turnoff during background illumination in mouse rod photoreceptors.

Modulation of phosphodiesterase6 turnoff during background illumination in mouse rod photoreceptors.

http://www.wikidata.org/entity/Q37361112

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Melanopsin contributions to irradiance coding in the thalamo-cortical visual system Background light produces a recoverin-dependent modulation of activated-rhodopsin lifetime in mouse rods.Adaptive potentiation in rod photoreceptors after light exposure Calcium sets the physiological value of the dominant time constant of saturated mouse rod photoresponse recovery.Lessons from photoreceptors: turning off g-protein signaling in living cells.Channel modulation and the mechanism of light adaptation in mouse rods Rhodopsin kinase and recoverin modulate phosphodiesterase during mouse photoreceptor light adaptation.Function of the asparagine 74 residue of the inhibitory γ-subunit of retinal rod cGMP-phophodiesterase (PDE) in vivo.Activation and quenching of the phototransduction cascade in retinal cones as inferred from electrophysiology and mathematical modeling Effect of the ILE86TER mutation in the γ subunit of cGMP phosphodiesterase (PDE6) on rod photoreceptor signaling.Loss of caveolin-1 impairs retinal function due to disturbance of subretinal microenvironment A novel Ca2+-feedback mechanism extends the operating range of mammalian rods to brighter light.Functional mapping of interacting regions of the photoreceptor phosphodiesterase (PDE6) γ-subunit with PDE6 catalytic dimer, transducin, and regulator of G-protein signaling9-1 (RGS9-1).cAMP controls rod photoreceptor sensitivity via multiple targets in the phototransduction cascade.Modulation of mouse rod response decay by rhodopsin kinase and recoverin.Kinetics of turn-offs of frog rod phototransduction cascade Night blindness and the mechanism of constitutive signaling of mutant G90D rhodopsin Light adaptation alters inner retinal inhibition to shape OFF retinal pathway signaling.Effects of Ca2+, Mg2+, and myristoylation on guanylyl cyclase activating protein 1 structure and stability The retinal cGMP phosphodiesterase gamma-subunit - a chameleon Detection of single photons by toad and mouse rods.Phenotype-genotype correlations in autosomal dominant retinitis pigmentosa caused by RHO, D190N Modulation of mouse rod photoreceptor responses by Grb14 protein.Adaptation of mammalian photoreceptors to background light: putative role for direct modulation of phosphodiesterase.Silencing of tuberin enhances photoreceptor survival and function in a preclinical model of retinitis pigmentosa (an american ophthalmological society thesis).Light-dependent phosphorylation of the gamma subunit of cGMP-phophodiesterase (PDE6gamma) at residue threonine 22 in intact photoreceptor neurons.Rod metabolic demand drives progression in retinopathies.Knockout of GARPs and the β-subunit of the rod cGMP-gated channel disrupts disk morphogenesis and rod outer segment structural integrity.Replacing the rod with the cone transducin subunit decreases sensitivity and accelerates response decay.Effect of knocking down the insulin receptor on mouse rod responses.ATP consumption by mammalian rod photoreceptors in darkness and in light.A role for GCAP2 in regulating the photoresponse. Guanylyl cyclase activation and rod electrophysiology in GUCA1B knock-out mice.Light adaptation and the evolution of vertebrate photoreceptors.The contribution of inner and outer retinal photoreceptors to infra-slow oscillations in the rat olivary pretectal nucleus.Role of recoverin in rod photoreceptor light adaptation.Multiple hypothalamic cell populations encoding distinct visual information.

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Modulation of phosphodiesterase6 turnoff during background illumination in mouse rod photoreceptors.

http://www.wikidata.org/entity/Q37361112

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scientific article published on February 2008

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vetenskaplig artikel

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Modulation of phosphodiesteras ...... n in mouse rod photoreceptors.

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Modulation of phosphodiesteras ...... n in mouse rod photoreceptors.

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Modulation of phosphodiesteras ...... n in mouse rod photoreceptors.

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Modulation of phosphodiesteras ...... n in mouse rod photoreceptors.

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Modulation of phosphodiesteras ...... n in mouse rod photoreceptors.

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Modulation of phosphodiesteras ...... n in mouse rod photoreceptors.

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JNEUROSCI.2973-07.2008

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Journal of Neuroscience

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Modulation of phosphodiesteras ...... on in mouse rod photoreceptors

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Alexander M Dizhoor

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Igor V Peshenko

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Kerstin M Janisch

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Michael L Woodruff

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Stephen H Tsang

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P2860

Opsin activation of transduction in the rods of dark-reared Rpe65 knockout mice

Essential role for RGS9 in opiate action

RGS-Rz and RGS9-2 proteins control mu-opioid receptor desensitisation in CNS: the role of activated Galphaz subunits

Recoverin regulates light-dependent phosphodiesterase activity in retinal rods

Role of guanylate cyclase-activating proteins (GCAPs) in setting the flash sensitivity of rod photoreceptors

The Y99C mutation in guanylyl cyclase-activating protein 1 increases intracellular Ca2+ and causes photoreceptor degeneration in transgenic mice.

Measurement of cytoplasmic calcium concentration in the rods of wild-type and transducin knock-out mice.

Phosphorylation by cyclin-dependent protein kinase 5 of the regulatory subunit of retinal cGMP phosphodiesterase. I. Identification of the kinase and its role in the turnoff of phosphodiesterase in vitro.

Phosphorylation of the gamma subunit of the retinal photoreceptor cGMP phosphodiesterase by the cAMP-dependent protein kinase and its effect on the gamma subunit interaction with other proteins.

GAP-independent termination of photoreceptor light response by excess gamma subunit of the cGMP-phosphodiesterase.

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2064-2074

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10.1523/JNEUROSCI.2973-07.2008

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18305241

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Photoreceptor protein

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