Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development. - Wikidata - wikimedia - TriplyDB

Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development.

Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development.

http://www.wikidata.org/entity/Q37361326

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Arachidonate 15-lipoxygenase type B knockdown leads to reduced lipid accumulation and inflammation in atherosclerosis 15-Lipoxygenase 1 interacts with phosphatidylethanolamine-binding protein to regulate MAPK signaling in human airway epithelial cells Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice Rabbit models for the study of human atherosclerosis: from pathophysiological mechanisms to translational medicine Resolution of inflammation: a new paradigm for the pathogenesis of periodontal diseases Mammalian lipoxygenases and their biological relevance Specialized pro-resolving mediators: endogenous regulators of infection and inflammation Functional and pathological roles of the 12- and 15-lipoxygenases Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators Eliminating or blocking 12/15-lipoxygenase reduces neutrophil recruitment in mouse models of acute lung injury Murine 12/15-lipoxygenase regulates ATP-binding cassette transporter G1 protein degradation through p38- and JNK2-dependent pathways.Human lipoxygenase pathway gene variation and association with markers of subclinical atherosclerosis in the diabetes heart study.Airway lipoxin A4 generation and lipoxin A4 receptor expression are decreased in severe asthma.Pro-resolving lipid mediators are leads for resolution physiology.Endogenous LXA4 circuits are determinants of pathological angiogenesis in response to chronic injury.Transgenic rabbit models for biomedical research: current status, basic methods and future perspectives.The relationship of hydroxyeicosatetraenoic acids and F2-isoprostanes to plaque instability in human carotid atherosclerosis Potential role of the lipoxygenase derived lipid mediators in atherosclerosis: leukotrienes, lipoxins and resolvins.15-lipoxygenase-1: a prooxidant enzyme.Role of 15-lipoxygenase/15-hydroxyeicosatetraenoic acid in hypoxia-induced pulmonary hypertension.Novel lipid mediators promote resolution of acute inflammation: impact of aspirin and statins.ROS-dependent Syk and Pyk2-mediated STAT1 activation is required for 15(S)-hydroxyeicosatetraenoic acid-induced CD36 expression and foam cell formation Monocyte 15-lipoxygenase gene expression requires ERK1/2 MAPK activity.αMβ₂ integrin activation prevents alternative activation of human and murine macrophages and impedes foam cell formation Nutrigenetic disruption of inflammation-resolution homeostasis and atherogenesis The macrophage foam cell as a target for therapeutic intervention.Specialized proresolving mediator targets for RvE1 and RvD1 in peripheral blood and mechanisms of resolution.Role of monocytes in atherogenesis.Macrophage-specific overexpression of interleukin-5 attenuates atherosclerosis in LDL receptor-deficient mice.Macrophage 12/15 lipoxygenase expression increases plasma and hepatic lipid levels and exacerbates atherosclerosis.Oral inflammatory diseases and systemic inflammation: role of the macrophage.Clues for new therapeutics in osteoporosis and periodontal disease: new roles for lipoxygenases?Thematic review series: The immune system and atherogenesis. Cytokine regulation of macrophage functions in atherogenesis.Biologic relevance of lipoxygenase isoforms in atherogenesis.Adenoviral 15-lipoxygenase-1 gene transfer inhibits hypoxia-induced proliferation of retinal microvascular endothelial cells in vitro Overexpression of 15-lipoxygenase-1 in oxygen-induced ischemic retinopathy inhibits retinal neovascularization via downregulation of vascular endothelial growth factor-A expression.Transgenic rabbit models for studying human cardiovascular diseases.Transfection of rat kidney with human 15-lipoxygenase suppresses inflammation and preserves function in experimental glomerulonephritis.Lipid peroxidation and decomposition--conflicting roles in plaque vulnerability and stability.A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease

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P2860

Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development.

http://www.wikidata.org/entity/Q37361326

description

1996 nî lūn-bûn

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1996年の論文

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1996年学术文章

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1996年学术文章

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1996年学术文章

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1996年学术文章

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1996年学术文章

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1996年學術文章

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1996年學術文章

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1996年學術文章

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name

Macrophage-mediated 15-lipoxyg ...... t atherosclerosis development.

@en

Macrophage-mediated 15-lipoxyg ...... t atherosclerosis development.

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type

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Macrophage-mediated 15-lipoxyg ...... t atherosclerosis development.

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Macrophage-mediated 15-lipoxyg ...... t atherosclerosis development.

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Macrophage-mediated 15-lipoxyg ...... t atherosclerosis development.

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Macrophage-mediated 15-lipoxyg ...... t atherosclerosis development.

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Journal of Clinical Investigation

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Macrophage-mediated 15-lipoxyg ...... t atherosclerosis development.

@en

P2093

E Herderick

http://www.w3.org/2001/XMLSchema#string

E Zsigmond

http://www.w3.org/2001/XMLSchema#string

H Kühn

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H S Kim

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J F Cornhill

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J Shen

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L Chan

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N V Guevara

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P2860

Molecular cloning and primary structure of human 15-lipoxygenase

Specific inflammatory cytokines regulate the expression of human monocyte 15-lipoxygenase

Evidence for a dominant role of lipoxygenase(s) in the oxidation of LDL by mouse peritoneal macrophages

Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man

Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity

Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions

Low density lipoprotein undergoes oxidative modification in vivo.

Tissue specific and position independent expression of the complete gene domain for chicken lysozyme in transgenic mice.

Gene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts.

In vivo gene therapy for hyperlipidemia: phenotypic correction in Watanabe rabbits by hepatic delivery of the rabbit LDL receptor gene.

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2201-2208

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10.1172/JCI119029

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10

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8941635

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atherosclerosis

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507668

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