In vivo gene therapy for hyperlipidemia: phenotypic correction in Watanabe rabbits by hepatic delivery of the rabbit LDL receptor gene.
about
A bovine papillomavirus-1 based vector restores the function of the low-density lipoprotein receptor in the receptor-deficient CHO-ldlA7 cell lineIntravenous administration of recombinant adenoviruses causes thrombocytopenia, anemia and erythroblastosis in rabbits.Long-term physiologically regulated expression of the low-density lipoprotein receptor in vivo using genomic DNA mini-gene constructsInhibition and regression of atherosclerotic lesions.LDLR-Gene therapy for familial hypercholesterolaemia: problems, progress, and perspectivesGene therapy to promote thromboresistance: local overexpression of tissue plasminogen activator to prevent arterial thrombosis in an in vivo rabbit modelRestoration of Physiologically Responsive Low-Density Lipoprotein Receptor-Mediated Endocytosis in Genetically Deficient Induced Pluripotent Stem Cells.Adenoviral vectors: development and application.Gene therapy for lipoprotein disorders.Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development.Episomal Nonviral Gene Therapy Vectors Slow Progression of Atherosclerosis in a Model of Familial Hypercholesterolemia.Microsomal transfer protein inhibitors, new approach for treatment of familial hypercholesterolemia, review of the literature, original findings, and clinical significance.RNAi-mediated knockdown of HMG CoA reductase enhances gene expression from physiologically regulated low-density lipoprotein receptor therapeutic vectors in vivo.Protein-free phospholipid emulsion treatment improved cardiopulmonary function and survival in porcine sepsis.The prospects of hepatic drug delivery and gene therapy.Intravenous gene therapy for familial hypercholesterolemia using ligand-facilitated transfer of a liposome:LDL receptor gene complex.A single intravenous dose of endotoxin rapidly alters serum lipoproteins and lipid transfer proteins in normal volunteers.Low-density lipoprotein receptor gene therapy using helper-dependent adenovirus produces long-term protection against atherosclerosis in a mouse model of familial hypercholesterolemia.The size of sinusoidal fenestrae is a critical determinant of hepatocyte transduction after adenoviral gene transfer.A sensitive noninvasive method for monitoring successful liver-directed gene transfer of the low-density lipoprotein receptor in Watanabe hyperlipidemic rabbits in vivo.
P2860
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P2860
In vivo gene therapy for hyperlipidemia: phenotypic correction in Watanabe rabbits by hepatic delivery of the rabbit LDL receptor gene.
description
1995 nî lūn-bûn
@nan
1995 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
In vivo gene therapy for hyper ...... the rabbit LDL receptor gene.
@ast
In vivo gene therapy for hyper ...... the rabbit LDL receptor gene.
@en
In vivo gene therapy for hyper ...... the rabbit LDL receptor gene.
@nl
type
label
In vivo gene therapy for hyper ...... the rabbit LDL receptor gene.
@ast
In vivo gene therapy for hyper ...... the rabbit LDL receptor gene.
@en
In vivo gene therapy for hyper ...... the rabbit LDL receptor gene.
@nl
prefLabel
In vivo gene therapy for hyper ...... the rabbit LDL receptor gene.
@ast
In vivo gene therapy for hyper ...... the rabbit LDL receptor gene.
@en
In vivo gene therapy for hyper ...... the rabbit LDL receptor gene.
@nl
P2093
P2860
P356
P1476
In vivo gene therapy for hyper ...... the rabbit LDL receptor gene.
@en
P2093
C D Montgomery
I Nasonkin
J D Roberts
R C Eisensmith
Y C Lin-Lee
P2860
P304
P356
10.1172/JCI117725
P407
P577
1995-02-01T00:00:00Z