DNA-binding drugs caught in action: the latest 3D pictures of drug-DNA complexes.
about
Conformational changes in DNA upon ligand binding monitored by circular dichroismIdentification of novel p53 pathway activating small-molecule compounds reveals unexpected similarities with known therapeutic agentsSelf-assembly of functionalizable two-component 3D DNA arrays through the induced formation of DNA three-way-junction branch points by supramolecular cylindersCrystal structures of Λ-[Ru(phen)₂dppz]²⁺ with oligonucleotides containing TA/TA and AT/AT steps show two intercalation modesIn and out of the minor groove: interaction of an AT-rich DNA with the drug CD27Binding of a designed anti-cancer drug to the central cavity of an RNA three-way junctionBeyond DNA binding - a review of the potential mechanisms mediating quinacrine's therapeutic activities in parasitic infections, inflammation, and cancersNew hopes from old drugs: revisiting DNA-binding small molecules as anticancer agents.Unraveling the sequence-dependent polymorphic behavior of d(CpG) steps in B-DNACombining aspects of the platinum anticancer drugs picoplatin and BBR3464 to synthesize a new family of sterically hindered dinuclear complexes; their synthesis, binding kinetics and cytotoxicity.Excursions in polynuclear platinum DNA binding.Structure-based DNA-targeting strategies with small molecule ligands for drug discovery.Competitive formation of DNA linkage isomers by a trinuclear platinum complex and the influence of pre-association.Investigation of the Reactivity of Oligodeoxynucleotides with Glyoxal and KMnO(4) Chemical Probes by Electrospray Ionization Mass Spectrometry.Synthesis, DNA binding, cellular DNA lesion and cytotoxicity of a series of new benzimidazole-based Schiff base copper(II) complexes.Spatially Resolved Quantification of Chromatin Condensation through Differential Local Rheology in Cell Nuclei Fluorescence Lifetime ImagingComparative evaluation of 11 in silico models for the prediction of small molecule mutagenicity: role of steric hindrance and electron-withdrawing groups.Spermine attenuates the action of the DNA intercalator, actinomycin D, on DNA binding and the inhibition of transcription and DNA replicationDNA recognition by synthetic constructs.Recent patents on therapeutic applications of the transcription factor decoy approach.Carbohydrate recognition at the minor-groove of the self-complementary duplex d(CGCGAATTCGCG)2 by a synthetic glyco-oligoamide.Template-assembled synthetic G-quadruplex (TASQ): a useful system for investigating the interactions of ligands with constrained quadruplex topologies.Light-Controlled Cellular Internalization and Cytotoxicity of Nucleic Acid-Binding Agents: Studies in Vitro and in Zebrafish Embryos.A Quinacrine Analogue Selective Against Gastric Cancer Cells: Insight from Biochemical and Biophysical Studies.Chiral heterobimetallic complexes targeting human DNA-topoisomerase Iα.A mechanistic approach for the DNA binding of chiral enantiomeric L- and D-tryptophan-derived metal complexes of 1,2-DACH: cleavage and antitumor activity.Binding and thermodynamics of REV peptide-ctDNA interaction.An RNA-Based Fluorescent Biosensor for High-Throughput Analysis of the cGAS-cGAMP-STING Pathway.Modulation of group I ribozyme activity by cationic porphyrinsSubtle recognition of 14-base pair DNA sequences via threading polyintercalation.Intercalation processes of copper complexes in DNA.DNA intercalator BMH-21 inhibits RNA polymerase I independent of DNA damage response.Custom-fit ruthenium(II) metallopeptides: a new twist to DNA binding with coordination compounds.The Role of the DNA Backbone in Minor-Groove Ligand Binding.Experimental validation of DNA interactions with nanoparticles derived from metal coupled amphiphiles.Closing the ring to bring up the light: synthesis of a hexacyclic acridinium cyanine dye.Validation of a computational docking methodology to identify the non-covalent binding site of ligands to DNA.Synthesis, Characterization and Luminescence Sensitivity with Variance in pH, DNA and BSA Binding Studies of Ru(II) Polypyridyl Complexes.A benzindole substituted carbazole cyanine dye: a novel targeting fluorescent probe for parallel c-myc G-quadruplexes.Single-Molecule Approach to DNA Minor-Groove Association Dynamics
P2860
Q27026184-1CFD7F0B-91C2-4EEA-855D-4AD06968CC75Q27318801-3D76AF9F-6B66-4BC8-977A-6FCA9F88FB5CQ27660073-1BD7A1B6-D240-4241-B7AC-7FE75BD1F2C9Q27681831-D82FE737-21FA-42B1-8541-5832A3C33EA3Q27684265-086A02EC-C77C-4B35-BBF7-EA2FA2ABC004Q27686681-B6180163-832D-4588-97E3-7AA64BF5D946Q28743513-CA189DC4-4AB7-44B2-9629-5843A77A8BE6Q33652585-6523EC13-D65E-4421-B97F-A17F53D15A05Q34312985-D94720C8-E385-4F6B-A51F-6620E0C5A7AFQ34377003-4D5645E7-8E89-4A08-B380-1FA7D080F798Q34480028-87BED3BA-7A13-4CAA-A95C-B4C492B9EB3BQ34697484-85ACBB6B-FB18-4BC8-9FBD-A737CA75B89FQ35072383-779D2819-FB17-4342-944C-FA6BB122B7DCQ35088856-37014218-1E9F-4C02-8FC3-3894C29D39D8Q35829015-E9B45573-C53B-454F-85D0-0295EA7C5959Q35893743-9F339314-BD0D-4189-B666-75ADA71D7AA1Q36182676-A4DCD28C-67A8-4CE7-A264-4E0B9BAB4A87Q36384664-64AB2C31-4231-4B99-B1DA-C72FF457CFE1Q37909253-AB74DB35-7C3F-4C2A-A709-9B79B65C4F27Q37948111-0923DFF6-C671-4D93-8C45-C440D3A39341Q38337887-23BE5225-91FC-485E-A5CE-F638D8E40511Q38344798-2FE72214-F3EC-4C96-A79F-4535A55C5FACQ38624989-C7F11026-92D4-46F3-933C-BB3A8E5097E5Q38730329-A875FA96-A8FF-4E25-A523-07E6306F7DBBQ39090105-DDC3D982-142B-4255-A547-83531443B3AFQ39647326-B8097C5F-AB52-44EE-B19C-50A6B2593F6FQ39648278-B2768EF1-5BE2-4D48-A107-2A37975B0680Q40434927-99D08B72-6B97-4A33-8E14-83DB2B4D833EQ41148710-C928062A-FCFE-410E-A6FD-87BDBE2DCB3CQ41885978-8C4E771D-9108-4DE2-B8CD-F471A27DF495Q42210092-E3D7CB46-C649-46EC-B7AC-8B355E888B34Q42847223-BDCB2341-ACE5-425D-9CDC-C67D852B9E3FQ44696717-246A777C-2141-4056-957F-E1DF07A73FD7Q48062497-A12770FA-D1A6-4C64-95E9-13A1451A0CE9Q48617031-0BB56DB5-0C28-4925-B3D9-ECF6825E1F6DQ50242485-FAE23C4B-0B6E-42CB-B963-40667909A485Q51083951-7243C1D6-2383-476A-B237-E6877BA3BF8EQ51153398-F1611D95-FA53-45C5-A738-556FD70BD319Q53182907-8DAB6432-AA74-4EAB-B0FE-7A93D8D9EF01Q57789618-3CC440FF-83D9-4717-BBCC-06854926F5FB
P2860
DNA-binding drugs caught in action: the latest 3D pictures of drug-DNA complexes.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
DNA-binding drugs caught in action: the latest 3D pictures of drug-DNA complexes.
@en
DNA-binding drugs caught in action: the latest 3D pictures of drug-DNA complexes.
@nl
type
label
DNA-binding drugs caught in action: the latest 3D pictures of drug-DNA complexes.
@en
DNA-binding drugs caught in action: the latest 3D pictures of drug-DNA complexes.
@nl
prefLabel
DNA-binding drugs caught in action: the latest 3D pictures of drug-DNA complexes.
@en
DNA-binding drugs caught in action: the latest 3D pictures of drug-DNA complexes.
@nl
P2860
P356
P1433
P1476
DNA-binding drugs caught in action: the latest 3D pictures of drug-DNA complexes
@en
P2093
Albert Canals
P2860
P304
P356
10.1039/B809873P
P407
P577
2008-11-07T00:00:00Z