about
A thymine tetrad in d(TGGGGT) quadruplexes stabilized with Tl+/Na+ ionsA crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplexFluorine in medicinal chemistry: β-fluorination of peripheral pyrrolidines attached to acridine ligands affects their interactions with G-quadruplex DNASolution Structure of a 2:1 Quindoline–c-MYC G-Quadruplex: Insights into G-Quadruplex-Interactive Small Molecule Drug DesignCrystal structure of a c-kit promoter quadruplex reveals the structural role of metal ions and water molecules in maintaining loop conformationThe high-resolution crystal structure of a parallel intermolecular DNA G-4 quadruplex/drug complex employing syn glycosyl linkagesStructural Studies on Dinuclear Ruthenium(II) Complexes That Bind Diastereoselectively to an Antiparallel Folded Human Telomere SequenceNew approaches of PARP-1 inhibitors in human lung cancer cells and cancer stem-like cells by some selected anthraquinone-derived small moleculesTwo-repeat human telomeric d(TAGGGTTAGGGT) sequence forms interconverting parallel and antiparallel G-quadruplexes in solution: distinct topologies, thermodynamic properties, and folding/unfolding kineticsDistance measurements between paramagnetic ligands bound to parallel stranded guanine quadruplexesTargeting human telomerase for cancer therapeutics.N-methylmesoporphyrin IX fluorescence as a reporter of strand orientation in guanine quadruplexesGaining insights into the small molecule targeting of the G-quadruplex in the c-MYC promoter using NMR and an allele-specific transcriptional assay.Structure-based DNA-targeting strategies with small molecule ligands for drug discovery.Automatic workflow for the classification of local DNA conformations.Bcl-2 promoter sequence G-quadruplex interactions with three planar and non-planar cationic porphyrins: TMPyP4, TMPyP3, and TMPyP2.Identification of new natural DNA G-quadruplex binders selected by a structure-based virtual screening approach.G-quadruplex structures and their interaction diversity with ligands.A Personal History of Quadruplex-Small Molecule Targeting.RNautophagy/DNautophagy possesses selectivity for RNA/DNA substratesHit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement.Sequence, stability, and structure of G-quadruplexes and their interactions with drugsDNA architecture: from G to Z.Structure of the human telomere in K+ solution: an intramolecular (3 + 1) G-quadruplex scaffoldRefinement of Generalized Born Implicit Solvation Parameters for Nucleic Acids and Their Complexes with Proteins.Supramolecular DNA recognition.Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics.A hitchhiker's guide to G-quadruplex ligands.DNA-binding drugs caught in action: the latest 3D pictures of drug-DNA complexes.The MOD-QM/MM Method: Applications to Studies of Photosystem II and DNA G-Quadruplexes.Human telomeric G-quadruplex: structures of DNA and RNA sequences.Synthesis of unimolecularly circular G-quadruplexes as prospective molecular probes.Methods for investigating G-quadruplex DNA/ligand interactions.The application of DNA and RNA G-quadruplexes to therapeutic medicines.Crystallography of DNA and RNA G-quadruplex nucleic acids and their ligand complexes.Studies on the site and mode of TMPyP4 interactions with Bcl-2 promoter sequence G-Quadruplexes.Versatile G-quadruplex-mediated strategies in label-free biosensors and logic systems.Seven essential questions on G-quadruplexes.Rational design of substituted diarylureas: a scaffold for binding to G-quadruplex motifsQuinazoline derivative from indigenous isolate, Nocardiopsis alba inhibits human telomerase enzyme.
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Structure of a G-quadruplex-ligand complex
@ast
Structure of a G-quadruplex-ligand complex
@en
Structure of a G-quadruplex-ligand complex
@nl
type
label
Structure of a G-quadruplex-ligand complex
@ast
Structure of a G-quadruplex-ligand complex
@en
Structure of a G-quadruplex-ligand complex
@nl
prefLabel
Structure of a G-quadruplex-ligand complex
@ast
Structure of a G-quadruplex-ligand complex
@en
Structure of a G-quadruplex-ligand complex
@nl
P1476
Structure of a G-quadruplex-ligand complex
@en
P2093
Gary N Parkinson
Shozeb M Haider
P304
P356
10.1016/S0022-2836(02)01354-2
P407
P577
2003-02-07T00:00:00Z