PLZF is a regulator of homeostatic and cytokine-induced myeloid development - Wikidata - wikimedia - TriplyDB

PLZF is a regulator of homeostatic and cytokine-induced myeloid development

PLZF is a regulator of homeostatic and cytokine-induced myeloid development

http://www.wikidata.org/entity/Q37362806

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MiR-221 influences effector functions and actin cytoskeleton in mast cells Functional antagonism between Sall4 and Plzf defines germline progenitors Plzf regulates germline progenitor self-renewal by opposing mTORC1 Implication of intracellular localization of transcriptional repressor PLZF in thyroid neoplasms.EOR-2 is an obligate binding partner of the BTB-zinc finger protein EOR-1 in Caenorhabditis elegans.Control of hepatic gluconeogenesis by the promyelocytic leukemia zinc finger protein.Alphabeta versus gammadelta lineage choice at the first TCR-controlled checkpoint Altered development of NKT cells, γδ T cells, CD8 T cells and NK cells in a PLZF deficient patient.ID'ing innate and innate-like lymphoid cells αβ versus γδ fate choice: counting the T-cell lineages at the branch point.Distinct signal transduction pathways downstream of the (P)RR revealed by microarray and ChIP-chip analyses PLZF regulates fibroblast growth factor responsiveness and maintenance of neural progenitors.PLZF regulates CCR6 and is critical for the acquisition and maintenance of the Th17 phenotype in human cells.NLRP7, Involved in Hydatidiform Molar Pregnancy (HYDM1), Interacts with the Transcriptional Repressor ZBTB16.POZ/BTB and AT-hook-containing zinc finger protein 1 (PATZ1) inhibits endothelial cell senescence through a p53 dependent pathway.The promyelocytic leukemia zinc finger protein: two decades of molecular oncology Transcription factor networks directing the development, function, and evolution of innate lymphoid effectors PLZF Controls the Expression of a Limited Number of Genes Essential for NKT Cell Function.Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells.Multiple layers of transcriptional regulation by PLZF in NKT-cell development RARα-PLZF oncogene inhibits C/EBPα function in myeloid cells.Developmental regulation of myeloerythroid progenitor function by the Lin28b-let-7-Hmga2 axis.The epigenetic regulator PLZF represses L1 retrotransposition in germ and progenitor cells.Analysis of the interaction between Zinc finger protein 179 (Znf179) and promyelocytic leukemia zinc finger (Plzf).Mechanistic target of rapamycin complex 1 is critical for invariant natural killer T-cell development and effector function.Gfi1 and Gfi1b: key regulators of hematopoiesis.Cooperation between both Wnt/{beta}-catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion.Concise Review: Balancing Stem Cell Self-Renewal and Differentiation with PLZF.Eya2, a Target Activated by Plzf, Is Critical for PLZF-RARA-Induced Leukemogenesis.Regulation of hematopoietic development by ZBTB transcription factors.Broad-complex, tramtrack, and bric-à-brac (BTB) proteins: Critical regulators of development.Identification of promoter within the first intron of Plzf gene expressed in carp spermatogonial stem cells.Identification of a novel promyelocytic leukemia zinc-finger isoform required for colorectal cancer cell growth and survival.Shape-shifting and tumor suppression by PLZF Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals.Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling.E and Id proteins influence invariant NKT cell sublineage differentiation and proliferation.Post transcriptional control of the epigenetic stem cell regulator PLZF by sirtuin and HDAC deacetylases.An early T cell lineage commitment checkpoint dependent on the transcription factor Bcl11b.The deubiquitinating enzyme USP37 regulates the oncogenic fusion protein PLZF/RARA stability.

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PLZF is a regulator of homeostatic and cytokine-induced myeloid development

http://www.wikidata.org/entity/Q37362806

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on September 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

PLZF is a regulator of homeostatic and cytokine-induced myeloid development

@en

PLZF is a regulator of homeostatic and cytokine-induced myeloid development.

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type

label

PLZF is a regulator of homeostatic and cytokine-induced myeloid development

@en

PLZF is a regulator of homeostatic and cytokine-induced myeloid development.

@nl

prefLabel

PLZF is a regulator of homeostatic and cytokine-induced myeloid development

@en

PLZF is a regulator of homeostatic and cytokine-induced myeloid development.

@nl

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Genes & Development

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PLZF is a regulator of homeostatic and cytokine-induced myeloid development

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Arthur Zelent

http://www.w3.org/2001/XMLSchema#string

Faiyaz Notta

http://www.w3.org/2001/XMLSchema#string

Jonathan D Licht

http://www.w3.org/2001/XMLSchema#string

Kim L Rice

http://www.w3.org/2001/XMLSchema#string

Louise Howell

http://www.w3.org/2001/XMLSchema#string

Sergei Doulatov

http://www.w3.org/2001/XMLSchema#string

P2860

LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia

Leukemia translocation gene, PLZF, is expressed with a speckled nuclear pattern in early hematopoietic progenitors

Fusion between a novel Krüppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia

Mutations in proto-oncogene GFI1 cause human neutropenia and target ELA2

The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions

SMRT corepressor interacts with PLZF and with the PML-retinoic acid receptor alpha (RARalpha) and PLZF-RARalpha oncoproteins associated with acute promyelocytic leukemia

The transcription factor PLZF directs the effector program of the NKT cell lineage

Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF

Id proteins at the cross-road of development and cancer

The acute promyelocytic leukemia-associated protein, promyelocytic leukemia zinc finger, regulates 1,25-dihydroxyvitamin D(3)-induced monocytic differentiation of U937 cells through a physical interaction with vitamin D(3) receptor

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2076-2087

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scholarly article

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10.1101/GAD.1788109

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17

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23

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2009-09-01T00:00:00Z

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26783195

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19723763

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2751973

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