LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia
about
PC3 prostate tumor-initiating cells with molecular profile FAM65Bhigh/MFI2low/LEF1low increase tumor angiogenesisInteractions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesisDigenic mutations in severe congenital neutropeniaAberrant Wnt Signaling in LeukemiaNeutrophils: Between host defence, immune modulation, and tissue injuryLEF-1 is a decisive transcription factor in neutrophil granulopoiesisGenes at human chromosome 5q31.1 regulate delayed-type hypersensitivity responses associated with Leishmania chagasi infectionDifferentiation of chronic lymphocytic leukemia B cells into immunoglobulin secreting cells decreases LEF-1 expression.Congenital neutropenia: diagnosis, molecular bases and patient management.NK-like homeodomain proteins activate NOTCH3-signaling in leukemic T-cells.Modified lentiviral LTRs allow Flp recombinase-mediated cassette exchange and in vivo tracing of "factor-free" induced pluripotent stem cells.Granulocyte colony-stimulating factor: molecular mechanisms of action during steady state and 'emergency' hematopoiesis.β-Catenin signaling increases during melanoma progression and promotes tumor cell survival and chemoresistanceLEF-1 is a prosurvival factor in chronic lymphocytic leukemia and is expressed in the preleukemic state of monoclonal B-cell lymphocytosisThe nuclear effector of Wnt-signaling, Tcf1, functions as a T-cell-specific tumor suppressor for development of lymphomas.Cyclic AMP responsive element binding proteins are involved in 'emergency' granulopoiesis through the upregulation of CCAAT/enhancer binding protein βA novel Bcr-Abl-mTOR-eIF4A axis regulates IRES-mediated translation of LEF-1Lef1DeltaN binds beta-catenin and increases osteoblast activity and trabecular bone mass.Peroxisomal lipid synthesis regulates inflammation by sustaining neutrophil membrane phospholipid composition and viability.Characterization of LEF1 High Expression and Novel Mutations in Adult Acute Lymphoblastic LeukemiaNeutrophil elastase in cyclic and severe congenital neutropenia.Non-steady-state hematopoiesis regulated by the C/EBPβ transcription factor.Pathogenesis of ELANE-mutant severe neutropenia revealed by induced pluripotent stem cellsCharacterisation of Neutropenia-Associated Neutrophil Elastase Mutations in a Murine Differentiation Model In Vitro and In Vivo.Rewiring of the inferred protein interactome during blood development studied with the tool PPICompare.Bmi1 overexpression in the cerebellar granule cell lineage of mice affects cell proliferation and survival without initiating medulloblastoma formation.Wnt3a stimulates maturation of impaired neutrophils developed from severe congenital neutropenia patient-derived pluripotent stem cells.Adult T-cell leukemia cells overexpress Wnt5a and promote osteoclast differentiation.Genetic heterogeneity in severe congenital neutropenia: how many aberrant pathways can kill a neutrophil?PLZF is a regulator of homeostatic and cytokine-induced myeloid developmentRunx2 and bone morphogenic protein 2 regulate the expression of an alternative Lef1 transcript during osteoblast maturation.A late-lineage murine neutrophil precursor population exhibits dynamic changes during demand-adapted granulopoiesisLymphoid enhancer binding factor-1 (LEF1) expression as a prognostic factor in adult acute promyelocytic leukemia.Pathophysiologic mechanisms, clinical features and treatment of idiopathic neutropenia.The role of transcription factors in the guidance of granulopoiesis.B-lineage transcription factors and cooperating gene lesions required for leukemia development.Wnt signaling in leukemias and myeloma: T-cell factors are in control.Cellular stress pathways in pediatric bone marrow failure syndromes: many roads lead to neutropenia.G-CSF: filgrastim, lenograstim and biosimilars.C/EBPa-mediated activation of microRNAs 34a and 223 inhibits Lef1 expression to achieve efficient reprogramming into macrophages.
P2860
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P2860
LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
LEF-1 is crucial for neutrophi ...... uced in congenital neutropenia
@ast
LEF-1 is crucial for neutrophi ...... uced in congenital neutropenia
@en
LEF-1 is crucial for neutrophi ...... uced in congenital neutropenia
@en-gb
LEF-1 is crucial for neutrophi ...... uced in congenital neutropenia
@nl
type
label
LEF-1 is crucial for neutrophi ...... uced in congenital neutropenia
@ast
LEF-1 is crucial for neutrophi ...... uced in congenital neutropenia
@en
LEF-1 is crucial for neutrophi ...... uced in congenital neutropenia
@en-gb
LEF-1 is crucial for neutrophi ...... uced in congenital neutropenia
@nl
prefLabel
LEF-1 is crucial for neutrophi ...... uced in congenital neutropenia
@ast
LEF-1 is crucial for neutrophi ...... uced in congenital neutropenia
@en
LEF-1 is crucial for neutrophi ...... uced in congenital neutropenia
@en-gb
LEF-1 is crucial for neutrophi ...... uced in congenital neutropenia
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
LEF-1 is crucial for neutrophi ...... uced in congenital neutropenia
@en
P2093
Christopher Baum
Cornelia Zeidler
Gunnar Cario
Julia Skokowa
Karin Battmer
Karl Welte
Manuela Germeshausen
Matthias Eder
Michaela Scherr
Murat Uenalan
P2860
P2888
P304
P3181
P356
10.1038/NM1474
P407
P577
2006-10-01T00:00:00Z
P5875
P6179
1018919185