Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage.
about
Decreased metalloproteinase production as a response to mechanical pressure in human cartilage: a mechanism for homeostatic regulationDrugs in development: bisphosphonates and metalloproteinase inhibitorsRepression of anti-proliferative factor Tob1 in osteoarthritic cartilageArticular cartilage and changes in arthritis. An introduction: cell biology of osteoarthritisMithramycin downregulates proinflammatory cytokine-induced matrix metalloproteinase gene expression in articular chondrocytesMesenchymal stem cell therapy in the treatment of osteoarthritis: reparative pathways, safety and efficacy - a reviewMolecular targets in arthritis and recent trends in nanotherapyCytokine networking of chondrocyte dedifferentiation in vitro and its implications for cell-based cartilage therapyThe role of changes in extracellular matrix of cartilage in the presence of inflammation on the pathology of osteoarthritisDeletion of Dual Specificity Phosphatase 1 Does Not Predispose Mice to Increased Spontaneous OsteoarthritisDiscovery and characterization of a novel inhibitor of matrix metalloprotease-13 that reduces cartilage damage in vivo without joint fibroplasia side effectsStructural insights into triple-helical collagen cleavage by matrix metalloproteinase 1Biochemical markers of ongoing joint damage in rheumatoid arthritis--current and future applications, limitations and opportunities.Roles of microRNA and signaling pathway in osteoarthritis pathogenesisSite-specific analysis of gene expression in early osteoarthritis using the Pond-Nuki model in dogsADAM-10 protein is present in human articular cartilage primarily in the membrane-bound form and is upregulated in osteoarthritis and in response to IL-1alpha in bovine nasal cartilageTissue inhibitor of metalloproteinases-4 (TIMP-4) gene expression is increased in human osteoarthritic femoral head cartilageInsulin-like growth factor 1 blocks collagen release and down regulates matrix metalloproteinase-1, -3, -8, and -13 mRNA expression in bovine nasal cartilage stimulated with oncostatin M in combination with interleukin 1alphaIntegrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networksCheminformatics-based drug design approach for identification of inhibitors targeting the characteristic residues of MMP-13 hemopexin domainSecretory leukocyte protease inhibitor suppresses the inflammation and joint damage of bacterial cell wall-induced arthritisParathyroid hormone activation of matrix metalloproteinase-13 transcription requires the histone acetyltransferase activity of p300 and PCAF and p300-dependent acetylation of PCAFFibronectin fragment activation of proline-rich tyrosine kinase PYK2 mediates integrin signals regulating collagenase-3 expression by human chondrocytes through a protein kinase C-dependent pathwaySubstrate specificity of human collagenase 3 assessed using a phage-displayed peptide library.Pathologic indicators of degradation and inflammation in human osteoarthritic cartilage are abrogated by exposure to n-3 fatty acids.Cross-relaxation imaging of human patellar cartilage in vivo at 3.0T.Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes.Articular Cartilage of the Human Knee Joint: In Vivo Multicomponent T2 Analysis at 3.0 T.Protease degradomics: mass spectrometry discovery of protease substrates and the CLIP-CHIP, a dedicated DNA microarray of all human proteases and inhibitors.Blockade of advanced glycation end-product formation restores ischemia-induced angiogenesis in diabetic miceCleavage of fibromodulin in cartilage explants involves removal of the N-terminal tyrosine sulfate-rich region by proteolysis at a site that is sensitive to matrix metalloproteinase-13.A critical role for the membrane-type 1 matrix metalloproteinase in collagen phagocytosis.High throughput screening of potentially selective MMP-13 exosite inhibitors utilizing a triple-helical FRET substrate.The effect of early hyaluronic acid delivery on the development of an acute articular cartilage lesion in a sheep model.Association between genetic polymorphisms of MMP8 and the risk of steroid-induced osteonecrosis of the femoral head in the population of northern China.Correlation between MMP-13 and HDAC7 expression in human knee osteoarthritis.Pleiotropic roles of matrix metalloproteinases in tumor angiogenesis: contrasting, overlapping and compensatory functions.The use of cleavage site specific antibodies to delineate protein processing and breakdown pathways.Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development.Physiological concentrations of soluble uric acid are chondroprotective and anti-inflammatory.
P2860
Q21195655-440B5757-A6D6-4C97-AE7D-8D82613FA7E4Q24795847-41CBED1D-EAA9-41EC-8680-D3A3AA79DF9BQ24803700-806C25E5-D8BE-46AB-AB91-647573DDACFCQ24805351-B96446BE-D6E8-4BB2-B165-66F62E761048Q24817080-CEF4DB71-44B9-4C25-BB9A-2CEC86D95643Q26745714-7B93A807-C949-4BC4-B3D0-3577A1C8A8E1Q26783466-0096C512-FC95-491D-B9B9-4729914DA446Q26998702-E75C1C28-0DB4-4427-943C-C607401BBCDEQ27011498-26A1D285-19FB-41BD-8C46-C33833E73815Q27343137-D67D1C5B-FCB6-4A3E-81CD-BC0EEF5F76F5Q27646616-7BE805B9-559E-4560-8BED-4FAF30841374Q27670630-92DAA5CD-B77F-473B-9791-F12FE53CA599Q27687777-085CEBBC-0AB2-4477-857E-49B926ECE7E2Q28069429-A4534965-9D3B-41F3-A6DE-956244B31AD2Q28211978-6F225892-84CE-4B6E-A784-692ECC3040B5Q28213603-0C514878-4297-4F3D-9326-9A2F682EFBCFQ28214460-D79BF96E-D403-4BC9-8B37-B53AE7B7E104Q28348472-BEBB28D2-D684-42CA-A9CB-FBBAE17F6CF5Q28474080-8CFDB781-B187-47C9-94B8-EAE7EB14C8C8Q28475366-0A0B4B88-8383-4960-A1AC-17A79F4247DFQ28572864-61E13EFD-8EC8-4A04-B098-0D4277C0A5D4Q28578422-D77AAF26-4C8C-4560-8F7E-04CC9AF4C5DCQ30433820-99DB2F1D-C28B-450E-AB06-EE64EC89338AQ30656278-E5928B15-7E9B-4E59-984C-FE6FC7019ED1Q30836366-1366EAD4-116F-4EB6-A4C2-CC3DB6739E67Q30857143-4DBE434C-0912-4560-9A81-A803D14FDBFBQ30931885-09ECE210-D421-4C2A-8750-F7EA547D5BA2Q30961324-E3FE2536-8AEE-422C-B1E3-C744DE69D1C3Q31094862-4F102F09-01DA-4153-AABB-AE2150A1E38AQ31146191-4280832D-5EDB-402C-A67D-3659DD4CAC9CQ33195733-DD0B0F6E-4738-46BF-B85A-85CEB569D14FQ33257523-9362D20F-A2CE-4AC8-86C9-06E446186B13Q33325058-590926EE-D964-4586-95D2-7AC2CEBB8984Q33499146-2E10D50F-8354-4C24-A1C3-CDEBCD6C7082Q33595264-04EED7A8-CA13-445F-9542-D4F249886AC4Q33637251-4B4DD83A-98B1-4D29-80E5-AF6831458A5DQ33665623-7017DD95-1835-45F3-BCD8-3BA50F53C507Q33706655-AD99DC2D-139E-4150-B1A6-4A715480D9B0Q33706862-81F1CDC0-EFA0-4DEF-BC7E-32F7CC9236C6Q33725818-B2CD9A3C-75D9-4F87-B818-1C5E2319BDDE
P2860
Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 1997
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Enhanced cleavage of type II c ...... arthritic articular cartilage.
@en
Enhanced cleavage of type II c ...... arthritic articular cartilage.
@nl
type
label
Enhanced cleavage of type II c ...... arthritic articular cartilage.
@en
Enhanced cleavage of type II c ...... arthritic articular cartilage.
@nl
prefLabel
Enhanced cleavage of type II c ...... arthritic articular cartilage.
@en
Enhanced cleavage of type II c ...... arthritic articular cartilage.
@nl
P2093
P2860
P356
P1476
Enhanced cleavage of type II c ...... arthritic articular cartilage.
@en
P2093
Billinghurst RC
Dahlberg L
Diekmann O
Mitchell P
P2860
P304
P356
10.1172/JCI119316
P407
P577
1997-04-01T00:00:00Z