Nasal anti-CD3 antibody ameliorates lupus by inducing an IL-10-secreting CD4+ CD25- LAP+ regulatory T cell and is associated with down-regulation of IL-17+ CD4+ ICOS+ CXCR5+ follicular helper T cells.
about
Oral immune therapy: targeting the systemic immune system via the gut immune system for the treatment of inflammatory bowel diseaseInducing and Administering Tregs to Treat Human DiseaseInduction of immunological tolerance by oral anti-CD3The effects of TLR activation on T-cell development and differentiationTh22 cells in allergic diseaseCutting edge: human latency-associated peptide+ T cells: a novel regulatory T cell subset.Induction of regulatory T cells decreases adipose inflammation and alleviates insulin resistance in ob/ob miceIn vivo induction of Tr1 cells via mucosal dendritic cells and AHR signaling.T cells as therapeutic targets in SLE.Distinct and complementary roles for Aspergillus fumigatus-specific Tr1 and Foxp3+ regulatory T cells in humans and mice.Mucosal anti-CD3 monoclonal antibody attenuates collagen-induced arthritis that is associated with induction of LAP+ regulatory T cells and is enhanced by administration of an emulsome-based Th2-skewing adjuvant.Immunotherapeutic strategies in autoimmune uveitisMurine models of systemic lupus erythematosusAnti-CD3 antibody ameliorates experimental autoimmune uveitis by inducing both IL-10 and TGF-β dependent regulatory T cells.Interleukin-17 expression positively correlates with disease severity of lupus nephritis by increasing anti-double-stranded DNA antibody production in a lupus model induced by activated lymphocyte derived DNA.In vivo anti-LAP mAb enhances IL-17/IFN-γ responses and abrogates anti-CD3-induced oral tolerance.Impaired circulating CD4+ LAP+ regulatory T cells in patients with acute coronary syndrome and its mechanistic study.Interferon-inducible gene 202b controls CD8(+) T cell-mediated suppression in anti-DNA Ig peptide-treated (NZB × NZW) F1 lupus mice.The dysregulation of cytokine networks in systemic lupus erythematosus.The current concept of T (h) 17 cells and their expanding role in systemic lupus erythematosus.Antigen microarrays identify CNS-produced autoantibodies in RRMS.Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice.Lipids and lipid-reactive antibodies as biomarkers for multiple sclerosis.IL-10-dependent Tr1 cells attenuate astrocyte activation and ameliorate chronic central nervous system inflammationNasal vaccination with troponin reduces troponin specific T-cell responses and improves heart function in myocardial ischemia-reperfusion injury.Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway.Suppression of murine SLE by oral anti-CD3: inducible CD4+CD25-LAP+ regulatory T cells control the expansion of IL-17+ follicular helper T cells.Regulatory T cell (Treg) subsets return in patients with refractory lupus following stem cell transplantation, and TGF-beta-producing CD8+ Treg cells are associated with immunological remission of lupusIL-21 and T follicular helper cells.Th17 cells in rheumatoid arthritis and systemic lupus erythematosus.CD8⁺ Treg cells associated with decreasing disease activity after intravenous methylprednisolone pulse therapy in lupus nephritis with heavy proteinuria.Interleukin-17 and systemic lupus erythematosus: current concepts.Review article: novel methods for the treatment of non-alcoholic steatohepatitis - targeting the gut immune system to decrease the systemic inflammatory response without immune suppression.The role of decay accelerating factor in environmentally induced and idiopathic systemic autoimmune disease.Role of LAP+CD4+ T cells in the tumor microenvironment of colorectal cancer.Signals that influence T follicular helper cell differentiation and function.Therapeutic potential of IL-27 in systemic lupus erythematosus.Multiple checkpoints keep follicular helper T cells under control to prevent autoimmunity.IL-17 in systemic lupus erythematosusUnderstanding the development and function of T follicular helper cells.
P2860
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P2860
Nasal anti-CD3 antibody ameliorates lupus by inducing an IL-10-secreting CD4+ CD25- LAP+ regulatory T cell and is associated with down-regulation of IL-17+ CD4+ ICOS+ CXCR5+ follicular helper T cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Nasal anti-CD3 antibody amelio ...... R5+ follicular helper T cells.
@en
Nasal anti-CD3 antibody amelio ...... R5+ follicular helper T cells.
@nl
type
label
Nasal anti-CD3 antibody amelio ...... R5+ follicular helper T cells.
@en
Nasal anti-CD3 antibody amelio ...... R5+ follicular helper T cells.
@nl
prefLabel
Nasal anti-CD3 antibody amelio ...... R5+ follicular helper T cells.
@en
Nasal anti-CD3 antibody amelio ...... R5+ follicular helper T cells.
@nl
P2860
P1476
Nasal anti-CD3 antibody amelio ...... R5+ follicular helper T cells.
@en
P2093
Francisco J Quintana
Henry Yim Wu
P2860
P304
P356
10.4049/JIMMUNOL.181.9.6038
P407
P577
2008-11-01T00:00:00Z