about
The hexamer structure of Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexesA crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replicationThe C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus ProductionStructure-Based Mutational Analysis of the NS3 Helicase from Dengue VirusCrystal Structure of the NS3 Protease-Helicase from Dengue VirusInsights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 proteinFlexibility between the protease and helicase domains of the dengue virus NS3 protein conferred by the linker region and its functional implicationsCrystal Structure of the Dengue Virus Methyltransferase Bound to a 5′-Capped Octameric RNAVisualizing the Determinants of Viral RNA Recognition by Innate Immune Sensor RIG-IStructural Insights into RNA Recognition by RIG-IDefining the functional determinants for RNA surveillance by RIG-IStructure of the NS2B-NS3 protease from Zika virus after self-cleavageCrystal structure of unlinked NS2B-NS3 protease from Zika virusThe linker region of NS3 plays a critical role in the replication and infectivity of hepatitis C virus.The C-terminal 50 amino acid residues of dengue NS3 protein are important for NS3-NS5 interaction and viral replicationFlexibility of NS5 Methyltransferase-Polymerase Linker Region Is Essential for Dengue Virus Replication.Molecular basis for specific viral RNA recognition and 2'-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5)Towards the design of antiviral inhibitors against flaviviruses: the case for the multifunctional NS3 protein from Dengue virus as a target.Duplex RNA activated ATPases (DRAs): platforms for RNA sensing, signaling and processing.Zika Virus Protease: An Antiviral Drug Target.Structural Dynamics of Zika Virus NS2B-NS3 Protease Binding to Dipeptide Inhibitors.Structural characterization of the linked NS2B-NS3 protease of Zika virus.Toward a crystal-clear view of the viral RNA sensing and response by RIG-I-like receptors.Functional interplay among the flavivirus NS3 protease, helicase, and cofactors.The flavivirus NS2B-NS3 protease-helicase as a target for antiviral drug development.Chikungunya virus nsP4 RNA-dependent RNA polymerase core domain displays detergent-sensitive primer extension and terminal adenylyltransferase activities.Luteolin restricts dengue virus replication through inhibition of the proprotein convertase furin.High-resolution HDX-MS reveals distinct mechanisms of RNA recognition and activation by RIG-I and MDA5.The RIG-I ATPase core has evolved a functional requirement for allosteric stabilization by the Pincer domain.NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication.Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor.Luteolin escape mutants of dengue virus map to prM and NS2B and reveal viral plasticity during maturation.RIG-I-Like Receptors as Novel Targets for Pan-Antivirals and Vaccine Adjuvants Against Emerging and Re-Emerging Viral Infections.Towards the Design of Flavivirus Helicase/NTPase Inhibitors: Crystallographic and Mutagenesis Studies of the Dengue Virus NS3 Helicase Catalytic DomainStructures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitorsStructures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitorsRIG-I Activation by a Designer Short RNA Ligand Protects Human Immune Cells against Dengue Virus Infection without Causing CytotoxicityStructural insights into RNA recognition by the Chikungunya virus nsP2 helicaseLC-MS assay targeting the mycobacterial indirect aminoacylation pathway uncovers glutaminase activities of the non-discriminating aspartyl-synthetaseStructure-guided design of immunomodulatory RNAs specifically targeting the cytoplasmic viral RNA sensor RIG-I
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Dahai Luo
@ast
Dahai Luo
@en
Dahai Luo
@es
Dahai Luo
@nl
Dahai Luo
@sl
type
label
Dahai Luo
@ast
Dahai Luo
@en
Dahai Luo
@es
Dahai Luo
@nl
Dahai Luo
@sl
prefLabel
Dahai Luo
@ast
Dahai Luo
@en
Dahai Luo
@es
Dahai Luo
@nl
Dahai Luo
@sl
P1053
J-6022-2012
P106
P1153
14020135800
P31
P3829
P496
0000-0001-7637-7275
P569
2000-01-01T00:00:00Z