High-resolution HDX-MS reveals distinct mechanisms of RNA recognition and activation by RIG-I and MDA5.
about
A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replicationKinetic discrimination of self/non-self RNA by the ATPase activity of RIG-I and MDA5Short-interference RNAs: becoming medicines.Intracellular detection of viral nucleic acids.When your cap matters: structural insights into self vs non-self recognition of 5' RNA by immunomodulatory host proteins.Analysis of phosphoinositide 3-kinase inhibitors by bottom-up electron-transfer dissociation hydrogen/deuterium exchange mass spectrometry.Effects of type 1 diabetes-associated IFIH1 polymorphisms on MDA5 function and expression.Establishing the role of ATP for the function of the RIG-I innate immune sensorAn IFIH1 gene polymorphism associated with risk for autoimmunity regulates canonical antiviral defence pathways in Coxsackievirus infected human pancreatic islets.HDX reveals the conformational dynamics of DNA sequence specific VDR co-activator interactions.Conserved RNA-binding specificity of polycomb repressive complex 2 is achieved by dispersed amino acid patches in EZH2.Combined roles of ATP and small hairpin RNA in the activation of RIG-I revealed by solution-based analysis.Conformational dynamics of 1-deoxy-d-xylulose 5-phosphate synthase on ligand binding revealed by H/D exchange MS.Deciphering of interactions between platinated DNA and HMGB1 by hydrogen/deuterium exchange mass spectrometry.RIG-I-Like Receptors as Novel Targets for Pan-Antivirals and Vaccine Adjuvants Against Emerging and Re-Emerging Viral Infections.Unified mechanisms for self-RNA recognition by RIG-I Singleton-Merten syndrome variants
P2860
Q27321114-C17B4E25-B372-4AC3-B7C8-99AA36F4D317Q35716846-5F1846DB-C919-4978-B756-35CA02777CEEQ36347546-8B45E4BF-20FF-49F4-AEFD-E3CB4315122AQ37374825-BE636086-41D6-45A5-915C-4377B1FD67C8Q37568730-5589E1CF-8AF6-4BE6-A796-CC532C07DCABQ38288444-B7DAF8D8-C394-4FA0-B70D-DE4FCAF85C47Q38589318-1B8EFFA3-692D-4F3D-96C4-951C7B800D14Q38835196-42F46C9E-62A8-492A-8576-B7B2CBDE8E22Q39613796-31680E66-9DBB-4A5E-A627-E86164612C0FQ42377219-68F9C077-6A4B-44F5-B456-7A8163E42813Q46252089-D9701235-84D5-409C-A347-FD2289313788Q47551803-C5F0CDAE-8562-4AEB-9884-7235F25BB310Q48241056-284014E6-FC36-4A25-9D71-8ED6A054D8A5Q51045898-BFF3CEB0-5790-483D-B876-D0164D3C7BF1Q55454646-D31E61B3-2BC1-4980-9C38-D566B0D71AFDQ56531142-F86FADAD-CF1D-4E46-B8D0-5FAF86397AA3
P2860
High-resolution HDX-MS reveals distinct mechanisms of RNA recognition and activation by RIG-I and MDA5.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
High-resolution HDX-MS reveals ...... activation by RIG-I and MDA5.
@en
type
label
High-resolution HDX-MS reveals ...... activation by RIG-I and MDA5.
@en
prefLabel
High-resolution HDX-MS reveals ...... activation by RIG-I and MDA5.
@en
P2093
P2860
P356
P1476
High-resolution HDX-MS reveals ...... d activation by RIG-I and MDA5
@en
P2093
Hui Yee Yong
Nantika Panutdaporn
P2860
P304
P356
10.1093/NAR/GKU1329
P577
2014-12-24T00:00:00Z