Hypoglycemic effect of insulin-like growth factor-1 in mice lacking insulin receptors.
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Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advancesA novel domain of caveolin-2 that controls nuclear targeting: regulation of insulin-specific ERK activation and nuclear translocation by caveolin-2The differential effects of pp120 (Ceacam 1) on the mitogenic action of insulin and insulin-like growth factor 1 are regulated by the nonconserved tyrosine 1316 in the insulin receptorSafety, tolerability, and pharmacokinetics of the anti-IGF-1R monoclonal antibody figitumumab in patients with refractory adrenocortical carcinomaThe forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expressionStearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscleThe adverse events profile of anti-IGF-1R monoclonal antibodies in cancer therapyInsulin-like growth factor-1 deficiency and metabolic syndromeInsulin-like growth factor 2 and the insulin receptor, but not insulin, regulate fetal hepatic glycogen synthesisEffects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistanceIdentification of sirm, a novel insulin-regulated SH3 binding protein that associates with Grb-2 and FYNRole of insulin-like growth factor-binding protein 5 (IGFBP5) in organismal and pancreatic beta-cell growthInhibition of vagally mediated immune-to-brain signaling by vanadyl sulfate speeds recovery from sickness.IGF-1 receptor as an alternative receptor for metabolic signaling in insulin receptor-deficient muscle cells.The HMGA1-IGF-I/IGFBP system: a novel pathway for modulating glucose uptake.Insulin and insulin-like growth factor-1 receptors act as ligand-specific amplitude modulators of a common pathway regulating gene transcription.ROCK inhibition as a therapy for spinal muscular atrophy: understanding the repercussions on multiple cellular targetsUrocortin 3 activates AMPK and AKT pathways and enhances glucose disposal in rat skeletal muscle.Elucidation of the molecular envenomation strategy of the cone snail Conus geographus through transcriptome sequencing of its venom duct.Genetic engineering in mice: impact on insulin signalling and action.Conditional VHL gene deletion causes hypoglycemic death associated with disproportionately increased glucose uptake by hepatocytes through an upregulated IGF-I receptor.Lifespan extension by caloric restriction: an aspect of energy metabolism.Glucose metabolism and pancreatic defects in spinal muscular atrophyUrocortin 3 transgenic mice exhibit a metabolically favourable phenotype resisting obesity and hyperglycaemia on a high-fat diet.Continuous subcutaneous IGF-1 therapy via insulin pump in a patient with Donohue syndromeLong-lived hypopituitary Ames dwarf mice are resistant to the detrimental effects of high-fat diet on metabolic function and energy expenditure.Development of endometrial carcinoma in a patient with leprechaunism (donohue syndrome).Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2.Insulin-like growth factor-1 improves diabetic cardiomyopathy through antioxidative and anti-inflammatory processes along with modulation of Akt/GSK-3β signaling in ratsElevated systolic blood pressure in male GH transgenic mice is age dependent.Defective insulin secretion in pancreatic beta cells lacking type 1 IGF receptor.Evidence that IRS-2 phosphorylation is required for insulin action in hepatocytes.Insulin receptor-deficient cells as a new tool for dissecting complex interplay in insulin and insulin-like growth factors.Essential role of insulin and insulin-like growth factor 1 receptor signaling in cardiac development and function.Increased IGFR activity and glucose transport in cultured skeletal muscle from insulin receptor null mice.Oilseeds ameliorate metabolic parameters in male mice, while contained lignans inhibit 3T3-L1 adipocyte differentiation in vitro.Insulin-like growth factor 1 (IGF-1)-induced twist expression is involved in the anti-apoptotic effects of the IGF-1 receptor.Englitazone administration to late pregnant rats produces delayed body growth and insulin resistance in their fetuses and neonates.The Gordon Wilson Lecture. Lessons about the control of glucose homeostasis and the pathogenesis of diabetes from knockout mice.Childhood obesity and insulin resistance in a Yucatan mini-piglet model: putative roles of IGF-1 and muscle PPARs in adipose tissue activity and development.
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Hypoglycemic effect of insulin-like growth factor-1 in mice lacking insulin receptors.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1997
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
Hypoglycemic effect of insulin-like growth factor-1 in mice lacking insulin receptors.
@en
Hypoglycemic effect of insulin-like growth factor-1 in mice lacking insulin receptors.
@nl
type
label
Hypoglycemic effect of insulin-like growth factor-1 in mice lacking insulin receptors.
@en
Hypoglycemic effect of insulin-like growth factor-1 in mice lacking insulin receptors.
@nl
prefLabel
Hypoglycemic effect of insulin-like growth factor-1 in mice lacking insulin receptors.
@en
Hypoglycemic effect of insulin-like growth factor-1 in mice lacking insulin receptors.
@nl
P2093
P2860
P356
P1476
Hypoglycemic effect of insulin-like growth factor-1 in mice lacking insulin receptors.
@en
P2093
P2860
P304
P356
10.1172/JCI119438
P407
P577
1997-05-01T00:00:00Z