The antiapoptotic protein Bcl-xL negatively regulates the bone-resorbing activity of osteoclasts in mice.
about
Cardiac deletion of Smyd2 is dispensable for mouse heart developmentNIK stabilization in osteoclasts results in osteoporosis and enhanced inflammatory osteolysis.The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis.GIV/girdin links vascular endothelial growth factor signaling to Akt survival signaling in podocytes independent of nephrin.Genetic mouse models for bone studies--strengths and limitationsFOXO1 inhibits osteoclastogenesis partially by antagnozing MYC.Intracellular and extracellular ATP coordinately regulate the inverse correlation between osteoclast survival and bone resorptionTAK1 is essential for osteoclast differentiation and is an important modulator of cell death by apoptosis and necroptosis.Advances in osteoclast biology reveal potential new drug targets and new roles for osteoclastsConditional abrogation of Atm in osteoclasts extends osteoclast lifespan and results in reduced bone mass.Regulation of the autophagic bcl-2/beclin 1 interaction.Lessons from gain- and loss-of-function models of pro-survival Bcl2 family proteins: implications for targeted therapy.Participation of GATA-3 in regulation of bone healing through transcriptional upregulation of bcl-xL expression.
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The antiapoptotic protein Bcl-xL negatively regulates the bone-resorbing activity of osteoclasts in mice.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 14 September 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The antiapoptotic protein Bcl- ...... tivity of osteoclasts in mice.
@en
The antiapoptotic protein Bcl- ...... tivity of osteoclasts in mice.
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type
label
The antiapoptotic protein Bcl- ...... tivity of osteoclasts in mice.
@en
The antiapoptotic protein Bcl- ...... tivity of osteoclasts in mice.
@nl
prefLabel
The antiapoptotic protein Bcl- ...... tivity of osteoclasts in mice.
@en
The antiapoptotic protein Bcl- ...... tivity of osteoclasts in mice.
@nl
P2093
P2860
P356
P1476
The antiapoptotic protein Bcl- ...... tivity of osteoclasts in mice.
@en
P2093
Kozo Nakamura
Lothar Hennighausen
Masaki Nakamura
Mitsuyasu Iwasawa
Sakae Tanaka
Shigeaki Kato
Takashi Nakamura
Takumi Matsumoto
Tetsuro Yasui
Toru Akiyama
P2860
P304
P356
10.1172/JCI39819
P407
P577
2009-09-14T00:00:00Z