Recent approaches to improve the antitumor efficacy of temozolomide.
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Chinese Guidelines on the Diagnosis and Treatment of Melanoma (2015 Edition)A New Epigenetic Mechanism of Temozolomide Action in Glioma CellsA nanoparticle carrying the p53 gene targets tumors including cancer stem cells, sensitizes glioblastoma to chemotherapy and improves survival.Phase II trial of temozolomide for leptomeningeal metastases in patients with solid tumors.Quercetin abrogates chemoresistance in melanoma cells by modulating deltaNp73.Inhibition of multiple protective signaling pathways and Ad.5/3 delivery enhances mda-7/IL-24 therapy of malignant gliomaQuantitative relationship between guanine O(6)-alkyl lesions produced by Onrigin™ and tumor resistance by O(6)-alkylguanine-DNA alkyltransferase.Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequencesN-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomidePharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide.Hispidulin enhances the anti-tumor effects of temozolomide in glioblastoma by activating AMPK.Overcoming the challenges in the effective delivery of chemotherapies to CNS solid tumors.Encapsulation of temozolomide in a tumor-targeting nanocomplex enhances anti-cancer efficacy and reduces toxicity in a mouse model of glioblastomaO6-methylguanine DNA methyltransferase as a promising target for the treatment of temozolomide-resistant gliomasTherapeutic effect of TMZ-POH on human nasopharyngeal carcinoma depends on reactive oxygen species accumulation.Development of a preclinical therapeutic model of human brain metastasis with chemoradiotherapy.Prolonged cell cycle response of HeLa cells to low-level alkylation exposure.Small-molecule inhibitors of proteins involved in base excision repair potentiate the anti-tumorigenic effect of existing chemotherapeutics and irradiation.MicroRNAs as therapeutic targets in chemoresistance.Temozolomide does not impair gene therapy-mediated antitumor immunity in syngeneic brain tumor models.Temozolomide-based combination for advanced neuroendocrine neoplasms: a systematic review of the literature.DNA methylation and histone acetylation regulate the expression of MGMT and chemosensitivity to temozolomide in malignant melanoma cell lines.A stapled peptide antagonist of MDM2 carried by polymeric micelles sensitizes glioblastoma to temozolomide treatment through p53 activation.LRIG1 enhances chemosensitivity by modulating BCL-2 expression and receptor tyrosine kinase signaling in glioma cells.Apoptosis induction in human glioblastoma multiforme T98G cells upon temozolomide and quercetin treatmentTemozolomide-induced myelodysplasia.Enhancing the cytotoxicity of chemoradiation with radiation-guided delivery of anti-MGMT morpholino oligonucleotides in non-methylated solid tumors.Overcoming blood brain barrier with a dual purpose Temozolomide loaded Lactoferrin nanoparticles for combating glioma (SERP-17-12433).Unraveling the cytotoxic potential of Temozolomide loaded into PLGA nanoparticlesHistone Methylation by Temozolomide; A Classic DNA Methylating Anticancer Drug.Temozolomide and Pituitary Tumors: Current Understanding, Unresolved Issues, and Future Directions.
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Recent approaches to improve the antitumor efficacy of temozolomide.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Recent approaches to improve the antitumor efficacy of temozolomide.
@en
Recent approaches to improve the antitumor efficacy of temozolomide.
@nl
type
label
Recent approaches to improve the antitumor efficacy of temozolomide.
@en
Recent approaches to improve the antitumor efficacy of temozolomide.
@nl
prefLabel
Recent approaches to improve the antitumor efficacy of temozolomide.
@en
Recent approaches to improve the antitumor efficacy of temozolomide.
@nl
P1476
Recent approaches to improve the antitumor efficacy of temozolomide
@en
P2093
Grazia Graziani
Lucio Tentori
P304
P356
10.2174/092986709787002718
P577
2009-01-01T00:00:00Z