Native cone photoreceptor cyclic nucleotide-gated channel is a heterotetrameric complex comprising both CNGA3 and CNGB3: a study using the cone-dominant retina of Nrl-/- mice.
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AAV-mediated cone rescue in a naturally occurring mouse model of CNGA3-achromatopsiaThe disease-causing mutations in the carboxyl terminus of the cone cyclic nucleotide-gated channel CNGA3 subunit alter the local secondary structure and interfere with the channel active conformational change.Rim formation is not a prerequisite for distribution of cone photoreceptor outer segment proteins.The Na+/Ca2+, K+ exchanger NCKX4 is required for efficient cone-mediated visionDifferences in RDS trafficking, assembly and function in cones versus rods: insights from studies of C150S-RDSEarly-onset, slow progression of cone photoreceptor dysfunction and degeneration in CNG channel subunit CNGB3 deficiency.Grueneberg ganglion olfactory subsystem employs a cGMP signaling pathway.Long-term and age-dependent restoration of visual function in a mouse model of CNGB3-associated achromatopsia following gene therapyRDS in cones does not interact with the beta subunit of the cyclic nucleotide gated channel.CNGA3 deficiency affects cone synaptic terminal structure and function and leads to secondary rod dysfunction and degeneration.Endoplasmic reticulum stress-associated cone photoreceptor degeneration in cyclic nucleotide-gated channel deficiency.Molecular pathogenesis of achromatopsia associated with mutations in the cone cyclic nucleotide-gated channel CNGA3 subunitBiochemical characterization of cone cyclic nucleotide-gated (CNG) channel using the infrared fluorescence detection systemAchromatopsia caused by novel missense mutations in the CNGA3 gene.The B3 Subunit of the Cone Cyclic Nucleotide-gated Channel Regulates the Light Responses of Cones and Contributes to the Channel Structural FlexibilitycGMP accumulation causes photoreceptor degeneration in CNG channel deficiency: evidence of cGMP cytotoxicity independently of enhanced CNG channel function.The Na(+)/Ca(2+), K(+) exchanger 2 modulates mammalian cone phototransduction.Cones respond to light in the absence of transducin β subunit.Impaired cone function and cone degeneration resulting from CNGB3 deficiency: down-regulation of CNGA3 biosynthesis as a potential mechanism.Novel CNGA3 and CNGB3 mutations in two Pakistani families with achromatopsia.
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P2860
Native cone photoreceptor cyclic nucleotide-gated channel is a heterotetrameric complex comprising both CNGA3 and CNGB3: a study using the cone-dominant retina of Nrl-/- mice.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 04 July 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Native cone photoreceptor cycl ...... ominant retina of Nrl-/- mice.
@en
Native cone photoreceptor cycl ...... ominant retina of Nrl-/- mice.
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type
label
Native cone photoreceptor cycl ...... ominant retina of Nrl-/- mice.
@en
Native cone photoreceptor cycl ...... ominant retina of Nrl-/- mice.
@nl
prefLabel
Native cone photoreceptor cycl ...... ominant retina of Nrl-/- mice.
@en
Native cone photoreceptor cycl ...... ominant retina of Nrl-/- mice.
@nl
P2093
P2860
P1476
Native cone photoreceptor cycl ...... ominant retina of Nrl-/- mice.
@en
P2093
Alexander B Quiambao
Alexander V Matveev
J Browning Fitzgerald
Xi-Qin Ding
P2860
P304
P356
10.1111/J.1471-4159.2008.05548.X
P407
P577
2008-07-04T00:00:00Z