about
PNPASE regulates RNA import into mitochondriaIdentification and characterization of two related murine genes, Eat2a and Eat2b, encoding single SH2-domain adaptersc-MYC activates protein kinase A (PKA) by direct transcriptional activation of the PKA catalytic subunit beta (PKA-Cbeta) geneBORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma.Dysregulated TCL1 promotes multiple classes of mature B cell lymphoma.TRIM family proteins and their emerging roles in innate immunityTranscription factor IRF8 directs a silencing programme for TH17 cell differentiationImmunoglobulin class switch recombination is impaired in Atm-deficient miceICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cellsHLA class I and II genotype of the NCI-60 cell linesInterferon regulatory factor 8 (IRF8) interacts with the B cell lymphoma 6 (BCL6) corepressor BCORIdentification of the human homologue of mouse KIF4, a kinesin superfamily motor proteinA critical role for IL-21 in regulating immunoglobulin productionICSBP/IRF-8 differentially regulates antigen uptake during dendritic-cell development and affects antigen presentation to CD4+ T cellsCloning, expression and genetic mapping of the mouse SH3 domain protein, SH3D2B.A mutant collagen XIII alters intestinal expression of immune response genes and predisposes transgenic mice to develop B-cell lymphomas.(18)F-FDG-PET/CT imaging in an IL-6- and MYC-driven mouse model of human multiple myeloma affords objective evaluation of plasma cell tumor progression and therapeutic response to the proteasome inhibitor ixazomib.Routes to covalent catalysis by reactive selection for nascent protein nucleophilesA three-stage framework for gene expression data analysis by L1-norm support vector regression.Induction of a protein-targeted catalytic response in autoimmune prone mice: antibody-mediated cleavage of HIV-1 glycoprotein GP120.Mechanism-dependent selection of immunoglobulin gene library for obtaining covalent biocatalysts.NOTCH is part of the transcriptional network regulating cell growth and survival in mouse plasmacytomasIRF8 regulates myeloid and B lymphoid lineage diversificationGene disruption study reveals a nonredundant role for TRIM21/Ro52 in NF-kappaB-dependent cytokine expression in fibroblastsEef1a2 promotes cell growth, inhibits apoptosis and activates JAK/STAT and AKT signaling in mouse plasmacytomas.Irradiated Blm-deficient mice are a highly tumor prone model for analysis of a broad spectrum of hematologic malignancies.IL-6 and MYC collaborate in plasma cell tumor formation in mice.The structural complexity of the human BORIS gene in gametogenesis and cancer.Nfatc2 and Tob1 have non-overlapping function in T cell negative regulation and tumorigenesisLymphomas and high-level expression of murine leukemia viruses in CFW mice.Expression of a testis-specific form of Gal3st1 (CST), a gene essential for spermatogenesis, is regulated by the CTCF paralogous gene BORIS.Homeostatic defects in B cells deficient in the E3 ubiquitin ligase ARF-BP1 are restored by enhanced expression of MYCThe transcription factor IRF8 activates integrin-mediated TGF-β signaling and promotes neuroinflammation.Functional phosphorylation sites in the C-terminal region of the multivalent multifunctional transcriptional factor CTCFEfficiency alleles of the Pctr1 modifier locus for plasmacytoma susceptibilityA reporter mouse reveals lineage-specific and heterogeneous expression of IRF8 during lymphoid and myeloid cell differentiation.Autoantibodies to myelin basic protein catalyze site-specific degradation of their antigen.IL-6 transgenic mouse model for extraosseous plasmacytoma.IRF8 governs expression of genes involved in innate and adaptive immunity in human and mouse germinal center B cells.Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Herbert C Morse
@nl
Herbert C Morse
@sl
Herbert C. Morse
@en
Herbert C. Morse
@es
type
label
Herbert C Morse
@nl
Herbert C Morse
@sl
Herbert C. Morse
@en
Herbert C. Morse
@es
prefLabel
Herbert C Morse
@nl
Herbert C Morse
@sl
Herbert C. Morse
@en
Herbert C. Morse
@es
P106
P1153
7102129339
P21
P31
P496
0000-0002-9331-3705