Two amino acid substitutions convert a guanylyl cyclase, RetGC-1, into an adenylyl cyclase.
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Crystal structures of the catalytic domain of human soluble guanylate cyclaseNatural and engineered photoactivated nucleotidyl cyclases for optogenetic applicationsMolecular details of cAMP generation in mammalian cells: a tale of two systemsLinking enzyme sequence to function using Conserved Property Difference Locator to identify and annotate positions likely to control specific functionalityCrystal structure of the guanylyl cyclase Cya2The crystal structure of the catalytic domain of a eukaryotic guanylate cyclaseStructural Basis for Inhibition of Mammalian Adenylyl Cyclase by Calcium †Substrate specificity determinants of class III nucleotidyl cyclasesGuanylyl cyclase activity associated with putative bifunctional integral membrane proteins in Plasmodium falciparumEndocytosis and Trafficking of Natriuretic Peptide Receptor-A: Potential Role of Short Sequence MotifsIntracellular neuronal calcium sensor (NCS) protein VILIP-1 modulates cGMP signalling pathways in transfected neural cells and cerebellar granule neuronesMolecular determinants for cyclic nucleotide binding to the regulatory domains of phosphodiesterase 2AGuanylate cyclase in Dictyostelium discoideum with the topology of mammalian adenylate cyclaseAdenylyl cyclase Rv1264 from Mycobacterium tuberculosis has an autoinhibitory N-terminal domainMutational analysis of the Mycobacterium tuberculosis Rv1625c adenylyl cyclase: residues that confer nucleotide specificity contribute to dimerizationOrigin of asymmetry in adenylyl cyclases: structures of Mycobacterium tuberculosis Rv1900cCharacterization of phylogenetically distant members of the adenylate cyclase family from mycobacteria: Rv1647 from Mycobacterium tuberculosis and its orthologue ML1399 from M. lepraeIsofunctional Protein Subfamily Detection Using Data Integration and Spectral ClusteringPseudomonas aeruginosa exotoxin Y is a promiscuous cyclase that increases endothelial tau phosphorylation and permeabilityInhibition of adenylyl and guanylyl cyclase isoforms by the antiviral drug foscarnet.CyaG, a novel cyanobacterial adenylyl cyclase and a possible ancestor of mammalian guanylyl cyclases.Guanylyl cyclase-linked natriuretic peptide receptors: structure and regulation.Multiple lineage specific expansions within the guanylyl cyclase gene familyIdentification of amino acid residues involved in substrate specificity of plant acyl-ACP thioesterases using a bioinformatics-guided approachSupervised multivariate analysis of sequence groups to identify specificity determining residues.The Arabidopsis thaliana brassinosteroid receptor (AtBRI1) contains a domain that functions as a guanylyl cyclase in vitro.Guanylyl cyclase sees the light.Combining structure and sequence information allows automated prediction of substrate specificities within enzyme familiesNeurocalcin delta modulation of ROS-GC1, a new model of Ca(2+) signaling.Membrane Guanylate Cyclase catalytic Subdomain: Structure and Linkage with Calcium Sensors and BicarbonateGGDEF domain is homologous to adenylyl cyclase.Synechocystis strain PCC 6803 cya2, a prokaryotic gene that encodes a guanylyl cyclase.Signaling receptome: a genomic and evolutionary perspective of plasma membrane receptors involved in signal transduction.Calcium is the switch in the moonlighting dual function of the ligand-activated receptor kinase phytosulfokine receptor 1The Rhizobium etli cyaC product: characterization of a novel adenylate cyclase class.Mutational analysis gives insight into substrate preferences of a nucleotidyl cyclase from Mycobacterium aviumAllosteric control of cyclic di-GMP signaling.Nucleotidyl cyclase activity of particulate guanylyl cyclase A: comparison with particulate guanylyl cyclases E and F, soluble guanylyl cyclase and bacterial adenylyl cyclases CyaA and edema factorThe functional genomics of guanylyl cyclase/natriuretic peptide receptor-A: perspectives and paradigmsGAF domains: cyclic nucleotides come full circle.
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P2860
Two amino acid substitutions convert a guanylyl cyclase, RetGC-1, into an adenylyl cyclase.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on May 1998
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Two amino acid substitutions c ...... C-1, into an adenylyl cyclase.
@en
Two amino acid substitutions c ...... C-1, into an adenylyl cyclase.
@nl
type
label
Two amino acid substitutions c ...... C-1, into an adenylyl cyclase.
@en
Two amino acid substitutions c ...... C-1, into an adenylyl cyclase.
@nl
prefLabel
Two amino acid substitutions c ...... C-1, into an adenylyl cyclase.
@en
Two amino acid substitutions c ...... C-1, into an adenylyl cyclase.
@nl
P2093
P2860
P356
P1476
Two amino acid substitutions c ...... GC-1, into an adenylyl cyclase
@en
P2093
J B Hurley
J H Hurley
T R Miller
P2860
P304
P356
10.1073/PNAS.95.11.5993
P407
P577
1998-05-01T00:00:00Z