about
Identification and biophysical assessment of the molecular recognition mechanisms between the human haemopoietic cell kinase Src homology domain 3 and ALG-2-interacting protein XIdentification of a Src kinase SH3 binding site in the C-terminal domain of the human ErbB2 receptor tyrosine kinaseStructural recognition mechanisms between human Src homology domain 3 (SH3) and ALG-2-interacting protein X (Alix)Chemical libraries dedicated to protein-protein interactionsHeteronuclear NMR and soft docking: an experimental approach for a structural model of the cytochrome c553-ferredoxin complexStructural model of the Fe-hydrogenase/cytochrome c553 complex combining transverse relaxation-optimized spectroscopy experiments and soft docking calculationsThe crystal structure of the hexadeca-heme cytochrome Hmc and a structural model of its complex with cytochrome c(3)The cytochrome c3-[Fe]-hydrogenase electron-transfer complex: structural model by NMR restrained dockingStructural basis of membrane binding by Gla domains of vitamin K-dependent proteinsInteraction between the C-terminal domains of N and P proteins of measles virus investigated by NMRCrystal structure of the vaccinia virus DNA polymerase holoenzyme subunit D4 in complex with the A20 N-terminal domainExploring Selective Inhibition of the First Bromodomain of the Human Bromodomain and Extra-terminal Domain (BET) ProteinsProtein-Protein Interaction Inhibition (2P2I)-Oriented Chemical Library Accelerates Hit DiscoveryAtomic analysis of protein-protein interfaces with known inhibitors: the 2P2I databaseA Biochemical/Biophysical Assay Dyad for HTS-Compatible Triaging of Inhibitors of the HIV-1 Nef/Hck SH3 Interaction.A novel approach for assessing macromolecular complexes combining soft-docking calculations with NMR data.Molecular mapping of the RNA Cap 2'-O-methyltransferase activation interface between severe acute respiratory syndrome coronavirus nsp10 and nsp16.Conotoxins and structural biology: a prospective paradigm for drug discovery.Structural and genetic analyses reveal a key role in prophage excision for the TorI response regulator inhibitor.The type I/type II cytochrome c3 complex: an electron transfer link in the hydrogen-sulfate reduction pathway.GFscore: a general nonlinear consensus scoring function for high-throughput docking.Protein protein interaction inhibition (2P2I) combining high throughput and virtual screening: Application to the HIV-1 Nef proteinProtein-protein interaction inhibition (2P2I): fewer and fewer undruggable targets.An integrative in silico methodology for the identification of modulators of macrophage migration inhibitory factor (MIF) tautomerase activity.Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis.Coronavirus Nsp10, a critical co-factor for activation of multiple replicative enzymes.Chemical and structural lessons from recent successes in protein-protein interaction inhibition (2P2I).Structural basis for the interaction between the Golgi reassembly-stacking protein GRASP65 and the Golgi matrix protein GM130.2P2Idb: a structural database dedicated to orthosteric modulation of protein-protein interactions.Prevalence, specificity and determinants of lipid-interacting PDZ domains from an in-cell screen and in vitro binding experiments2P2I HUNTER: a tool for filtering orthosteric protein-protein interaction modulators via a dedicated support vector machine.Focused chemical libraries--design and enrichment: an example of protein-protein interaction chemical space.2P2Idb v2: update of a structural database dedicated to orthosteric modulation of protein-protein interactions.Modified cap group suberoylanilide hydroxamic acid histone deacetylase inhibitor derivatives reveal improved selective antileukemic activity.Identification of allosteric inhibitors blocking the hepatitis C virus polymerase NS5B in the RNA synthesis initiation step.Solution structure of HndAc: a thioredoxin-like domain involved in the NADP-reducing hydrogenase complexA peptide mimic of an antigenic loop of alpha-human chorionic gonadotropin hormone: solution structure and interaction with a llama V(HH) domain.Searching for the Holy Grail; protein-protein interaction analysis and modulation.Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology.Multiple orientations in a physiological complex: the pyruvate-ferredoxin oxidoreductase-ferredoxin system.
P50
Q24293548-F317EA6D-9170-4D53-9FB4-F93D060C7F77Q24297527-E2D87889-A56F-4E14-A21A-70E1EC473826Q24336937-9C5F8002-0780-4001-B32C-7D2D22AD68E7Q27010681-590C5928-4395-4C4B-8956-9F67736B4BEBQ27621663-7CC09B1E-0091-4648-A9F8-7DC366BBC544Q27622077-9EA5DA87-C418-4205-8D4D-1327BF82FE49Q27640109-336F35B0-BD6D-45F9-B27F-50E4E8941889Q27641746-C1D8B000-69C4-4B34-957E-1A0B22B7D621Q27641849-DCB8145D-67BB-471E-A946-F08242E5C38DQ27654052-9876F016-5B0B-49E9-BBEE-EE85C66A2078Q27682037-A7D8FCE2-8FA8-4C2F-A91E-CF0D57823AABQ27703506-375D603E-3C0A-435F-AAB6-7A9B16CEF226Q27704937-FAEB3A04-834B-4232-AD41-859B47EE7C32Q28473129-D2A997A6-BB0E-495A-B1B3-63FF111C59CBQ30009501-3A8CCCD7-6867-4931-BA85-47239EF60761Q30661015-DEF483A5-2B17-41C8-899E-EFD8DA12B77CQ30987080-6AD68590-34EC-4FFD-B3C2-EE37D359DAD8Q33206127-26EEA648-7169-46E3-BF18-FCF80C9018A7Q33221062-87C3DED2-4E37-43D0-9BA3-0976A6CFDAE7Q33225213-A3D6EF1D-E708-4F32-9B06-1318D8683E4CQ33251333-4D8FD840-4716-49E5-B69C-D4688717E69AQ33307477-57CCA962-C337-42DE-BF8C-F6EAC751ABFEQ33520065-F7C30192-C6AE-49BB-BA3D-7F18B28D9B36Q33635084-C3BED1CA-1922-407C-B298-8568D46BF539Q33803207-6F61899E-0FF2-432C-91F5-3B2F6BED22EDQ34170781-9B1A0230-732E-4262-AC9B-BE6D3BC67327Q34193676-EB8A3D8C-95C4-4AF2-A68D-5FFA256E12A1Q34493798-4DB79A37-804C-4990-83D1-27EA644B71CBQ34498023-E0EC2D51-C1F7-464B-9921-BEB065A4F821Q34579931-B4682753-070A-45F7-8549-AD2EFA35B40EQ35033136-7B85E7B4-12C5-468C-B887-77DC5734CA47Q35158672-6A1122FF-0C3A-498C-B294-7FCD950CF8E6Q39015083-910E5615-DEC5-4065-993C-992CDD101B2FQ39729668-1CB3101D-2D07-490B-A974-7D759BBC424AQ39827052-56E6DE0D-3CEB-4C8B-9FCA-34714045C60BQ41865670-3ABC794D-D8D2-45FB-867E-AA019546E88DQ41923129-7BC7DB02-8F3D-4454-9216-790385C2DCAFQ42530348-78F6A4D8-F8CB-44D4-9A7A-B8218936EAA1Q47394090-0046090C-DD4D-4BAF-A08C-2C2DA160E742Q48160970-5F777C01-A86D-48BF-AD3E-8C9340A83B5F
P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Xavier Morelli
@ast
Xavier Morelli
@en
Xavier Morelli
@es
Xavier Morelli
@nl
Xavier Morelli
@sl
type
label
Xavier Morelli
@ast
Xavier Morelli
@en
Xavier Morelli
@es
Xavier Morelli
@nl
Xavier Morelli
@sl
prefLabel
Xavier Morelli
@ast
Xavier Morelli
@en
Xavier Morelli
@es
Xavier Morelli
@nl
Xavier Morelli
@sl
P108
P1053
A-9218-2016
P106
P21
P31
P3829
P496
0000-0001-8101-7901