about
Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeletonNeutrophil activation via beta2 integrins (CD11/CD18): molecular mechanisms and clinical implicationsRegulation of blood and lymphatic vascular separation by signaling proteins SLP-76 and Syk.Critical but overlapping role of FcgammaRIII and FcgammaRIV in activation of murine neutrophils by immobilized immune complexesKinase pathways in chemoattractant-induced degranulation of neutrophils: the role of p38 mitogen-activated protein kinase activated by Src family kinasesTyrosine kinase inhibitors for the treatment of rheumatoid arthritisReprint of Neutrophil cell surface receptors and their intracellular signal transduction pathways.Neutrophil cell surface receptors and their intracellular signal transduction pathways.The absence of P2X7 receptors (P2rx7) on non-haematopoietic cells leads to selective alteration in mood-related behaviour with dysregulated gene expression and stress reactivity in mice.Resting murine neutrophils express functional alpha 4 integrins that signal through Src family kinases.Spleen tyrosine kinase Syk is critical for sustained leukocyte adhesion during inflammation in vivo.Optimization of important early ADME(T) parameters of NADPH oxidase-4 inhibitor molecules.The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitmentGenetic deficiency of Syk protects mice from autoantibody-induced arthritis.Neutrophil granulocytes recruited upon translocation of intestinal bacteria enhance graft-versus-host disease via tissue damage.Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation.Neutrophils are required for both the sensitization and elicitation phase of contact hypersensitivityThe phosphoinositide 3-kinase isoform PI3Kβ regulates osteoclast-mediated bone resorption in humans and mice.Differential regulatory role of pituitary adenylate cyclase-activating polypeptide in the serum-transfer arthritis model.What is the future of targeted therapy in rheumatology: biologics or small molecules?Phospholipase Cγ2 is required for basal but not oestrogen deficiency-induced bone resorption.Src and Syk kinases: key regulators of phagocytic cell activation.ITAM-based signaling beyond the adaptive immune response.The SYK tyrosine kinase: a crucial player in diverse biological functions.Evidence that IgE molecules mediate a spectrum of effects on mast cell survival and activation via aggregation of the FcepsilonRI.Immunoreceptor-like signaling by beta 2 and beta 3 integrins.Critical role of phospholipase Cgamma2 in integrin and Fc receptor-mediated neutrophil functions and the effector phase of autoimmune arthritis.MASP-1 induces a unique cytokine pattern in endothelial cells: a novel link between complement system and neutrophil granulocytes.The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase.The role of neutrophils in autoimmune diseases.Diverse novel functions of neutrophils in immunity, inflammation, and beyond.Phosphoinositide 3-OH kinase regulates integrin-dependent processes in neutrophils by signaling through its effector ARAP3.Electrogenic H+ pathway contributes to stimulus-induced changes of internal pH and membrane potential in intact neutrophils: role of cytoplasmic phospholipase A2.Dasatinib inhibits proinflammatory functions of mature human neutrophilsThe Syk Tyrosine Kinase Is Required for Skin Inflammation in an In Vivo Mouse Model of Epidermolysis Bullosa AcquisitaContribution of phopholipase D and a brefeldin A-sensitive ARF to chemoattractant-induced superoxide production and secretion of human neutrophils.Syk is required for integrin signaling in neutrophils.G-protein-coupled receptor signaling in Syk-deficient neutrophils and mast cells.Role for plastin in host defense distinguishes integrin signaling from cell adhesion and spreading.SLP-76 regulates Fcgamma receptor and integrin signaling in neutrophils.
P50
Q24293554-1A32AD89-58CD-4BE6-8C78-FA729F23FD4AQ28242335-6D52EBA3-FD6C-4923-814D-1AA3C6755DA6Q28588103-3CE53E93-A47C-4734-B802-47EDA84873F9Q28594601-5ED7A5CE-6F2A-4B76-AA1A-A6CB6D5EA9D2Q28646115-38A2F0B8-79C3-43D3-A32B-79CEADAB417AQ28674280-ED66F165-6561-44B4-B8C4-E05E03637D90Q30009522-73B7A17F-CBE2-4A33-A0C9-BF5521DC6A72Q30009577-0D4AD7EF-AD6A-4E0D-9229-71FA9D3CE3D7Q30540124-9678E6FD-26AA-49F4-BAAA-CC2D840A4415Q32133674-CFA1730F-C5C4-4E1C-B890-CCDF09750A2FQ33307614-62A08EF7-CC61-4411-A8FE-C551790D3B63Q34183160-0A852999-11F2-46B7-AFFD-489E2079D453Q34230548-B1FDEAC0-83F9-461B-B934-23F48D222B22Q34275410-ED7CE671-BC00-4343-AD0E-9936D9857C4CQ34420372-082204B4-7252-4EAF-876F-7BEE5F5153C6Q34920323-595BCDC4-FD9E-4966-9944-0F68D30540B4Q34924724-410F928D-B081-4530-A063-3C3A6DA253FDQ35040987-6B5B113B-3BFF-4695-8FFC-FAFA5DBCBF9AQ35061170-D8B00D2A-0116-4F83-9AE9-11C9976A5046Q35118364-A9A4870E-EB77-4850-9783-11C8CB8DFA58Q35697027-50583F48-6F95-4693-A36F-3A30DE24FB58Q36083524-5DB5274F-3D03-4E51-A41B-A594B7F78F5DQ36332906-38072D6B-3D6B-4AEF-91AF-4E584D7ACCE0Q36662082-17C8F28A-B776-43B2-84E8-762E8BD49F28Q36689929-B965C4A1-C82D-4F20-96F9-84E5AF64563BQ36959336-03A5CC6A-079A-4709-B68B-7FCDBE5BF872Q37234322-105A301D-E097-4411-815D-C0FA79C1DFCBQ37529606-14940438-C1CB-470E-B8FA-8B50A99EA049Q37647341-FCB7714C-C18D-43F5-8B0D-832E237370C3Q37985351-DE6FC320-6DC5-45E7-BF2A-9260745F363FQ38119206-65425804-0B65-4F75-9724-8A1E8651A848Q41545564-3E246423-1F41-4959-B013-1ACC40985B38Q41841917-3ECA2280-DFFB-47FF-9ED5-7A2F8C598DB6Q41885572-285C1FA6-893F-4030-9725-718715CA82D4Q41929292-9CC3EF8B-C4C0-41AD-9163-B62E766ED9FFQ43943398-B1E53C12-5142-44AF-860E-689F722A8C51Q43968751-2E89CC45-3345-4995-8BEF-0F48B2C6E089Q44280924-9799A25F-67DD-4621-A831-F4E43159DDF8Q44519041-DEAFC13E-3EDA-4632-85F8-F4331C6B9EE6Q44653982-6D97F649-0828-4CA2-9ED0-2CAC1FDFBEE8
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Attila Mocsai
@ast
Attila Mocsai
@en
Attila Mocsai
@es
Attila Mocsai
@nl
Attila Mocsai
@sl
type
label
Attila Mocsai
@ast
Attila Mocsai
@en
Attila Mocsai
@es
Attila Mocsai
@nl
Attila Mocsai
@sl
altLabel
Attila Mocsai
@en
prefLabel
Attila Mocsai
@ast
Attila Mocsai
@en
Attila Mocsai
@es
Attila Mocsai
@nl
Attila Mocsai
@sl
P106
P1153
6602896769
P21
P31
P496
0000-0002-0512-1157
P5463
Mócsai_Attila