Genetic deficiency of Syk protects mice from autoantibody-induced arthritis.
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K/BxN Serum-Transfer Arthritis as a Model for Human Inflammatory ArthritisTargeting Syk in Autoimmune Rheumatic DiseasesA Novel Triazolopyridine-Based Spleen Tyrosine Kinase Inhibitor That Arrests Joint InflammationTyrosine kinase inhibitors for the treatment of rheumatoid arthritisNeutrophil cell surface receptors and their intracellular signal transduction pathways.Mechanisms of Autoantibody-Induced Pathology.Getting Syk: spleen tyrosine kinase as a therapeutic target.Methotrexate and a spleen tyrosine kinase inhibitor cooperate to inhibit responses to peripheral blood B cells in rheumatoid arthritis.The arthritis severity locus Cia5a regulates the expression of inflammatory mediators including Syk pathway genes and proteases in pristane-induced arthritis.Neutrophil functions and autoimmune arthritis in the absence of p190RhoGAP: generation and analysis of a novel null mutation in mice.The phosphoinositide 3-kinase isoform PI3Kβ regulates osteoclast-mediated bone resorption in humans and mice.Selective inhibition of spleen tyrosine kinase (SYK) with a novel orally bioavailable small molecule inhibitor, RO9021, impinges on various innate and adaptive immune responses: implications for SYK inhibitors in autoimmune disease therapy.Differential regulatory role of pituitary adenylate cyclase-activating polypeptide in the serum-transfer arthritis model.Deletion of Syk in neutrophils prevents immune complex arthritisPhospholipase Cγ2 is required for basal but not oestrogen deficiency-induced bone resorption.Kinase inhibitors in the treatment of immune-mediated diseaseUrine/Plasma Neutrophil Gelatinase Associated Lipocalin Ratio Is a Sensitive and Specific Marker of Subclinical Acute Kidney Injury in Mice.Simultaneous inhibition of JAK and SYK kinases ameliorates chronic and destructive arthritis in mice.The SYK tyrosine kinase: a crucial player in diverse biological functions.Neutrophil-specific deletion of the CARD9 gene expression regulator suppresses autoantibody-induced inflammation in vivo.Arthritis severity locus Cia4 is an early regulator of IL-6, IL-1β, and NF-κB activators' expression in pristane-induced arthritis.Advances in rheumatoid arthritis animal models.Spleen tyrosine kinase inhibition in the treatment of autoimmune, allergic and autoinflammatory diseases.Emerging immunotherapies for rheumatoid arthritis.Intracellular signalling during neutrophil recruitment.PRT062607 Achieves Complete Inhibition of the Spleen Tyrosine Kinase at Tolerated Exposures Following Oral Dosing in Healthy VolunteersThe Syk Tyrosine Kinase Is Required for Skin Inflammation in an In Vivo Mouse Model of Epidermolysis Bullosa AcquisitaSpleen Tyrosine Kinase Inhibition Modulates p53 Activity.Whole-Genome Expression Profiling in Skin Reveals SYK As a Key Regulator of Inflammation in Experimental Epidermolysis Bullosa Acquisita.Lineage-Specific Analysis of Syk Function in Autoantibody-Induced Arthritis.Complex Role of Capsaicin-Sensitive Afferents in the Collagen Antibody-Induced Autoimmune Arthritis of the MouseRole of the Spleen Tyrosine Kinase Pathway in Driving Inflammation in IgA Nephropathy
P2860
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P2860
Genetic deficiency of Syk protects mice from autoantibody-induced arthritis.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Genetic deficiency of Syk protects mice from autoantibody-induced arthritis.
@ast
Genetic deficiency of Syk protects mice from autoantibody-induced arthritis.
@en
Genetic deficiency of Syk protects mice from autoantibody-induced arthritis.
@nl
type
label
Genetic deficiency of Syk protects mice from autoantibody-induced arthritis.
@ast
Genetic deficiency of Syk protects mice from autoantibody-induced arthritis.
@en
Genetic deficiency of Syk protects mice from autoantibody-induced arthritis.
@nl
prefLabel
Genetic deficiency of Syk protects mice from autoantibody-induced arthritis.
@ast
Genetic deficiency of Syk protects mice from autoantibody-induced arthritis.
@en
Genetic deficiency of Syk protects mice from autoantibody-induced arthritis.
@nl
P2860
P50
P356
P1476
Genetic deficiency of Syk protects mice from autoantibody-induced arthritis
@en
P2093
Edina Simon
P2860
P304
P356
10.1002/ART.27438
P577
2010-07-01T00:00:00Z