about
Mutations in the gene encoding C8orf38 block complex I assembly by inhibiting production of the mitochondria-encoded subunit ND1Mitochondrial respiratory chain supercomplexes are destabilized in Barth Syndrome patientsCrystal structure of the mitochondrial chaperone TIM9.10 reveals a six-bladed alpha-propellerHuman CIA30 is involved in the early assembly of mitochondrial complex I and mutations in its gene cause diseaseAnalysis of the assembly profiles for mitochondrial- and nuclear-DNA-encoded subunits into complex ITissue-specific splicing of an Ndufs6 gene-trap insertion generates a mitochondrial complex I deficiency-specific cardiomyopathyMitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARLPINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activityKeeping the immune system in check: a role for mitophagy.Inhibition of Bak activation by VDAC2 is dependent on the Bak transmembrane anchorPINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial bindingRole of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase ParkinSequestration and autophagy of mitochondria do not cut proteins across the board.Assembly of the Bak apoptotic pore: a critical role for the Bak protein α6 helix in the multimerization of homodimers during apoptosisAssembly of mitochondrial complex I and defects in disease.The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy.Atg8 family LC3/GABARAP proteins are crucial for autophagosome-lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation.Deciphering the Molecular Signals of PINK1/Parkin Mitophagy.Parkin and mitophagy in cancer.The porin VDAC2 is the mitochondrial platform for Bax retrotranslocation.Cost of a naturally occurring two-amino acid deletion in cytochrome c oxidase subunit 7A in Drosophila simulans.Bacteriophage Transcytosis Provides a Mechanism To Cross Epithelial Cell Layers.Autophagy induced during apoptosis degrades mitochondria and inhibits type I interferon secretion.Structure, function, and regulation of mitofusin-2 in health and disease.Autophagosome formation and cargo sequestration in the absence of LC3/GABARAPs.BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis.Analysis of mitochondrial subunit assembly into respiratory chain complexes using Blue Native polyacrylamide gel electrophoresis.Chapter 18 Analysis of respiratory chain complex assembly with radiolabeled nuclear- and mitochondrial-encoded subunits.YoungMito 2018: Report on the 1st International Mitochondria Meeting for Young ScientistsIdentification of PSD-95 in the Postsynaptic Density Using MiniSOG and EM TomographyAblation of tau causes an olfactory deficit in a murine model of Parkinson's diseaseLC3/GABARAPs drive ubiquitin-independent recruitment of Optineurin and NDP52 to amplify mitophagyParkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagyAssembly of nuclear DNA-encoded subunits into mitochondrial complex IV, and their preferential integration into supercomplex forms in patient mitochondriaMammalian Atg8 proteins regulate lysosome and autolysosome biogenesis through SNAREs
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Michael Lazarou
@ast
Michael Lazarou
@en
Michael Lazarou
@es
Michael Lazarou
@nl
Michael Lazarou
@sl
type
label
Michael Lazarou
@ast
Michael Lazarou
@en
Michael Lazarou
@es
Michael Lazarou
@nl
Michael Lazarou
@sl
prefLabel
Michael Lazarou
@ast
Michael Lazarou
@en
Michael Lazarou
@es
Michael Lazarou
@nl
Michael Lazarou
@sl
P106
P1153
10440332200
57204926320
P21
P31
P4012
P496
0000-0003-2150-5545