Translesional DNA synthesis through a C8-guanyl adduct of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in Vitro: REV1 inserts dC opposite the lesion, and DNA polymerase kappa potentially catalyzes extension reaction from the 3'-dC terminus
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Basis of Miscoding of the DNA Adduct N2,3-Ethenoguanine by Human Y-family DNA PolymerasesThe non-canonical protein binding site at the monomer-monomer interface of yeast proliferating cell nuclear antigen (PCNA) regulates the Rev1-PCNA interaction and Polζ/Rev1-dependent translesion DNA synthesis.DNA damage response curtails detrimental replication stress and chromosomal instability induced by the dietary carcinogen PhIP.Catalytic and non-catalytic roles of DNA polymerase κ in the protection of human cells against genotoxic stresses.Limited ability of DNA polymerase kappa to suppress benzo[a]pyrene-induced genotoxicity in vivo.
P2860
Translesional DNA synthesis through a C8-guanyl adduct of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in Vitro: REV1 inserts dC opposite the lesion, and DNA polymerase kappa potentially catalyzes extension reaction from the 3'-dC terminus
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 23 July 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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Translesional DNA synthesis th ...... action from the 3'-dC terminus
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Translesional DNA synthesis th ...... action from the 3'-dC terminus
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Translesional DNA synthesis th ...... action from the 3'-dC terminus
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Translesional DNA synthesis th ...... action from the 3'-dC terminus
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Translesional DNA synthesis th ...... action from the 3'-dC terminus
@en
Translesional DNA synthesis th ...... action from the 3'-dC terminus
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P2093
P2860
P356
P1476
Translesional DNA synthesis th ...... action from the 3'-dC terminus
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P2093
Chiho Seki
Chikahide Masutani
Fumio Hanaoka
Hirokazu Fukuda
Hitoshi Nakagama
Kenji Kamiya
Takashi Sugimura
Takehiko Nohmi
Takeji Takamura-Enya
Yuji Masuda
P2860
P304
25585-25592
P356
10.1074/JBC.M109.037259
P407
P577
2009-07-23T00:00:00Z