Tbx22null mice have a submucous cleft palate due to reduced palatal bone formation and also display ankyloglossia and choanal atresia phenotypes.
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Molecular basis of cleft palates in micePalatogenesis and cutaneous repair: A two-headed coinThe T-box gene family: emerging roles in development, stem cells and cancerSignaling networks in palate developmentCompetition between Jagged-Notch and Endothelin1 Signaling Selectively Restricts Cartilage Formation in the Zebrafish Upper FaceTooth agenesis and orofacial clefting: genetic brothers in arms?Microdeletion del(22)(q12.2) encompassing the facial development-associated gene, MN1 (meningioma 1) in a child with Pierre-Robin sequence (including cleft palate) and neurofibromatosis 2 (NF2): a case report and review of the literature.Avian facial morphogenesis is regulated by c-Jun N-terminal kinase/planar cell polarity (JNK/PCP) wingless-related (WNT) signaling.Rdh10 loss-of-function and perturbed retinoid signaling underlies the etiology of choanal atresia.Tmem26 is dynamically expressed during palate and limb development but is not required for embryonic survival.X-linked genes and risk of orofacial clefts: evidence from two population-based studies in Scandinavia.Bmpr1a signaling plays critical roles in palatal shelf growth and palatal bone formation.Genetics of nonsyndromic orofacial cleftsMutations in HYAL2, Encoding Hyaluronidase 2, Cause a Syndrome of Orofacial Clefting and Cor Triatriatum Sinister in Humans and MiceCellular and Molecular Mechanisms of PalatogenesisMolecular signaling along the anterior-posterior axis of early palate development.Smad4-Irf6 genetic interaction and TGFβ-mediated IRF6 signaling cascade are crucial for palatal fusion in mice.MEMO1 drives cranial endochondral ossification and palatogenesis.Identification of candidate downstream targets of TGFβ signaling during palate development by genome-wide transcript profiling.The Role of Noncoding Genetic Variation in Isolated Orofacial Clefts.Examination of a palatogenic gene program in zebrafish.Analysis of human soft palate morphogenesis supports regional regulation of palatal fusion.Identification of causative variants in TXNL4A in Burn-McKeown syndrome and isolated choanal atresia.Constitutively active mutation of ACVR1 in oral epithelium causes submucous cleft palate in miceLoss-of-function mutation in the X-linked TBX22 promoter disrupts an ETS-1 binding site and leads to cleft palate.X-linked CHARGE-like Abruzzo-Erickson syndrome and classic cleft palate with ankyloglossia result from TBX22 splicing mutations.Small-molecule Wnt agonists correct cleft palates in Pax9 mutant mice in utero.Molecular and Cellular Mechanisms of Palate Development.A numerical classification system for cleft lip and palate in the dog.Creating diversity in mammalian facial morphology: a review of potential developmental mechanisms.Pbx loss in cranial neural crest, unlike in epithelium, results in cleft palate only and a broader midface.
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P2860
Tbx22null mice have a submucous cleft palate due to reduced palatal bone formation and also display ankyloglossia and choanal atresia phenotypes.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 31 July 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Tbx22null mice have a submucou ...... nd choanal atresia phenotypes.
@en
Tbx22null mice have a submucou ...... nd choanal atresia phenotypes.
@nl
type
label
Tbx22null mice have a submucou ...... nd choanal atresia phenotypes.
@en
Tbx22null mice have a submucou ...... nd choanal atresia phenotypes.
@nl
prefLabel
Tbx22null mice have a submucou ...... nd choanal atresia phenotypes.
@en
Tbx22null mice have a submucou ...... nd choanal atresia phenotypes.
@nl
P2093
P2860
P50
P356
P1476
Tbx22null mice have a submucou ...... and choanal atresia phenotypes
@en
P2093
Aya Hoshino
Gudrun E Moore
Lucy Bentley
Peter Hammond
Suresh Prajapati
P2860
P304
P356
10.1093/HMG/DDP368
P577
2009-07-31T00:00:00Z