about
ASPP1 and ASPP2 are new transcriptional targets of E2FMll5 is required for normal spermatogenesisSomatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin.Weaver Syndrome-Associated EZH2 Protein Variants Show Impaired Histone Methyltransferase Function In VitroThe clonal and mutational evolution spectrum of primary triple-negative breast cancersTITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data.The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalentPyClone: statistical inference of clonal population structure in cancer.Solution NMR structure and histone binding of the PHD domain of human MLL5.Impact of MLL5 expression on decitabine efficacy and DNA methylation in acute myeloid leukemia.Histological Transformation and Progression in Follicular Lymphoma: A Clonal Evolution Study.The oncogenic roles of DICER1 RNase IIIb domain mutations in ovarian Sertoli-Leydig cell tumors.Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution.CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumoursAtrophin controls developmental signaling pathways via interactions with Trithorax-likeSomatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation.Novel function of the cyclin A binding site of E2F in regulating p53-induced apoptosis in response to DNA damage.Clonal genotype and population structure inference from single-cell tumor sequencing.Ser392 phosphorylation regulates the oncogenic function of mutant p53.Ligation of CD40 potentiates Fas-mediated activation of the cysteine protease CPP32, cleavage of its death substrate PARP, and apoptosis in Ramos-Burkitt lymphoma B cells.CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor.Engineered in-vitro cell line mixtures and robust evaluation of computational methods for clonal decomposition and longitudinal dynamics in cancer.Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer.A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesisMdm2 Inhibits the Apoptotic Function of p53 Mainly by Targeting It for DegradationPharmacological systems analysis defines EIF4A3 functions in cell-cycle and RNA stress granule formation
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researcher
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հետազոտող
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P1153
35970451500
P31
P496
0000-0002-5370-4592
P569
2000-01-01T00:00:00Z